Adenosine Drug Card Flashcards

Questions and Answers

What is the trade name of Adenosine?

Adenosine Plus

Adensol

Adenosol

Adenocard (correct)

What is the classification of Adenosine?

Endogenous nucleoside, miscellaneous antidysrhythmic

What is the mechanism of action of Adenosine?

It decreases electrical conduction through the AV node and acts on sinus pacemaker cells.

What are the indications for Adenosine?

First line drug for most narrow-complex PSVT and dysrhythmias associated with bypass tracts. Signup and view all the answers

What are the contraindications for Adenosine?

Second or third degree AV block, Sick Sinus Syndrome, hypersensitivity, atrial flutter, atrial fibrillation, V-tach. Signup and view all the answers

Which of the following are adverse reactions of Adenosine? (Select all that apply)

Nausea and vomiting Signup and view all the answers

What are the drug interactions associated with Adenosine?

Methylxanthines (such as caffeine), Dipyridamole, and Carbamazepine. Signup and view all the answers

What is the dosage and administration of Adenosine for adults?

Initial dose: 6mg rapid IV bolus, followed by 20ml flush; Repeat dose: 12mg if no response. Signup and view all the answers

What is the onset and duration of Adenosine?

Onset: Immediate; Duration: 10 seconds. Signup and view all the answers

What are the special considerations for administering Adenosine?

Put the patient in slight reverse Trendelenburg position. Signup and view all the answers

Study Notes

Adenosine Overview

Trade name: Adenocard
Classification: Endogenous nucleoside, miscellaneous antidysrhythmic

Mechanism of Action

Formed from the breakdown of adenosine triphosphate (ATP); present in every cell.
Decreases electrical conduction through the AV node to slow supraventricular tachycardia without negative inotropic effects.
Acts directly on sinus pacemaker cells and vagal nerve terminals to reduce heart rate.
First-line treatment for paroxysmal supraventricular tachycardia (SVT) and assists in diagnostics for wide complex tachycardia.

Indications

First-line treatment for narrow-complex PSVT and dysrhythmias associated with bypass tracts, such as Wolff-Parkinson-White syndrome in adults and children.

Contraindications

Ineffective in converting rhythms like atrial flutter and fibrillation; contraindicated in second or third-degree AV block, Sick Sinus Syndrome, hypersensitivity, and V-tach.

Adverse Reactions

Possible reactions include lightheadedness, paresthesia, headache, diaphoresis, palpitations, chest pain, flushing, hypotension, shortness of breath (SOB), transient bradycardia, ventricular ectopy, nausea/vomiting (N/V).

Drug Interactions

Methylxanthines (caffeine, theophylline) can antagonize adenosine effects.
Dipyridamole may necessitate lower doses as it can enhance adenosine effects.
Carbamazepine might intensify adenosine's AV nodal blocking effects.

Dosage and Administration

Adults: Initial dose of 6 mg IV bolus over 1-3 seconds, followed by a 20 ml flush. If no response in 1-2 minutes, a 12 mg repeat dose can be administered similarly.
Pediatrics: Initial dose of 0.1 mg/kg, may double once with a maximum of 6 mg, given as a rapid IV bolus followed by a 5 ml flush.

Onset and Duration

Effects of IV administration are immediate, lasting approximately 10 seconds.

Special Considerations

Position the patient in slight reverse Trendelenburg before administration to optimize outcomes. Be prepared for a brief period of asystole during administration.

Description

Test your knowledge on adenosine with these flashcards. Learn about its trade name, classification, and mechanism of action. Perfect for pharmacology students or medical professionals looking to refresh their knowledge.