Addiction and High Risk Use
10 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following substances is NOT a psychotomimetic/hallucinogen?

  • Peyote (mescaline)
  • LSD-Acid
  • Cocaine
  • Barbiturates (correct)
  • Which of the following sources is NOT a book?

  • Fundamentals of Psychopharmacology by B.Leonard
  • Pharmacology by Rang, Dale, Ritter & Gardner
  • The Pharmacological Basis of Therapeutics by Goodman & Gilman
  • www.drugabuse.gov (correct)
  • Which of the following drugs is primarily used as a stimulant?

  • Ethanol
  • Methamphetamine (correct)
  • Cocaine
  • Pethidine
  • What is the primary effect of opioids on the CNS?

    <p>They alter both mood and perceptual state</p> Signup and view all the answers

    Which of the following is NOT a type of amphetamine?

    <p>Pethidine</p> Signup and view all the answers

    Which of the following drugs is NOT a CNS depressant?

    <p>Cocaine</p> Signup and view all the answers

    What is the primary effect of tobacco on the CNS?

    <p>It alters mood</p> Signup and view all the answers

    Which of the following drugs is primarily used as a hypnotic?

    <p>Barbiturates</p> Signup and view all the answers

    Which of the following drugs is NOT a substance of abuse?

    <p>Acetaminophen</p> Signup and view all the answers

    Which of the following sources is a website?

    <p><a href="http://www.drugabuse.gov">www.drugabuse.gov</a></p> Signup and view all the answers

    Study Notes

    High Risk Use and Addiction

    • High risk use: continued use of drugs despite severe social or legal consequences
    • Characteristics:
    • Temporary escape from reality becomes primary focus of life
    • Unafraid or unaware of consequences of behavior
    • Unbearable cravings drive behavior to obtain drugs

    Addiction

    • Defined as:
    • Inability to control amount and frequency of drug use
    • Irresistible cravings and urges for the substance
    • Continued use despite adverse effects
    • Denial of negative consequences
    • Tendency to abuse other mood-altering drugs or alcohol
    • Willingness to break the law to obtain the substance
    • Tolerance and withdrawal signs and symptoms

    Drug Abuse and Dependence

    • Drug abuse: use of a drug in a manner not approved by the culture, resulting in social disapproval
    • Non-medical drug use: recreational use of licit and illicit drugs for pleasurable effects
    • Drug dependence: syndrome in which an individual continues to take a drug due to pleasurable effects, despite adverse social or medical consequences

    Dose and Craving

    • Dose of drug often increased to maintain desired effect (habituation or adaptation)
    • Craving: uncontrolled desire to obtain and use drugs or substances an addict is dependent on

    Central Pathways and Mechanisms of Dependence

    • Main factors involved in drug dependence:
    • Reward (reinforcing)
    • Habituation
    • Aversive effect on abstinence (physical withdrawal syndrome)
    • Psychological changes resulting in craving
    • Neurobiological basis of reward and habituation:
    • Mesolimbic dopaminergic system
    • Release of dopamine in nucleus accumbens (NAc) by various mechanisms

    Other Transmitters Involved in Dependence

    • Noradrenergic system: involved in excessive sympathetic activity following withdrawal
    • Serotoninergic system: 5-HT uptake blockers or agonists decrease drug seeking behaviors
    • Amino acid systems (GABAergic and glutamatergic): interact with barbiturates, BDZs, and alcohol
    • Canabinoid action: via cannabinoid receptor (CB1)
    • Cholinergic systems: nicotine interacts with

    Mechanism of Habituation

    • Chronic use of drugs increases adenylate cyclase in N.Acc., leading to increased cAMP, G-proteins, and protein kinases
    • Protein kinases control activity of ion channels, leading to changes in neuronal activity

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Description

    This quiz explores the consequences of continued drug use despite severe social and legal repercussions, and how it can take over one's life. Learn about the characteristics of addiction and its effects on behavior.

    More Like This

    Drug Abuse and Addiction
    6 questions

    Drug Abuse and Addiction

    WellConnectedAlexandrite avatar
    WellConnectedAlexandrite
    Drugs and Society Chapters 1-6 Quiz
    100 questions
    Use Quizgecko on...
    Browser
    Browser