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Questions and Answers
What is the primary characteristic of ARDS?
What is the primary characteristic of ARDS?
Which of the following factors is a known cause of ARDS?
Which of the following factors is a known cause of ARDS?
What percentage of ARDS patients typically experience mild disease?
What percentage of ARDS patients typically experience mild disease?
What is the relationship between the severity of ARDS and mortality rates?
What is the relationship between the severity of ARDS and mortality rates?
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Which of the following is not an identified source of ARDS?
Which of the following is not an identified source of ARDS?
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Which symptom is NOT commonly associated with pulmonary embolism (PE)?
Which symptom is NOT commonly associated with pulmonary embolism (PE)?
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Which laboratory test is primarily used to diagnose pulmonary embolism?
Which laboratory test is primarily used to diagnose pulmonary embolism?
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What is a non-pharmacological method mentioned for the prevention of pulmonary embolism?
What is a non-pharmacological method mentioned for the prevention of pulmonary embolism?
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Which imaging technique is used to visualize the size and location of a pulmonary embolism?
Which imaging technique is used to visualize the size and location of a pulmonary embolism?
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Which of the following statements about the treatment of pulmonary embolism is incorrect?
Which of the following statements about the treatment of pulmonary embolism is incorrect?
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Which of the following conditions is a known risk factor for developing venous stasis?
Which of the following conditions is a known risk factor for developing venous stasis?
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What is a significant cause of injury to the vascular endothelium?
What is a significant cause of injury to the vascular endothelium?
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Which cancer types are linked to an increased risk of thrombosis?
Which cancer types are linked to an increased risk of thrombosis?
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What is a primary characteristic of a massive pulmonary embolism (PE)?
What is a primary characteristic of a massive pulmonary embolism (PE)?
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Which of the following describes a low-risk pulmonary embolism classification?
Which of the following describes a low-risk pulmonary embolism classification?
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Which of the following medications is often associated with a higher risk of thrombosis?
Which of the following medications is often associated with a higher risk of thrombosis?
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What physiological change is associated with hypercoagulability?
What physiological change is associated with hypercoagulability?
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Which of the following statements about immobility is true?
Which of the following statements about immobility is true?
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What effect does an increase in alveolar dead space have on gas exchange?
What effect does an increase in alveolar dead space have on gas exchange?
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What physiological response is triggered due to hypoxia in the lungs?
What physiological response is triggered due to hypoxia in the lungs?
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What is the main cause of shunting in the lungs during pulmonary embolism?
What is the main cause of shunting in the lungs during pulmonary embolism?
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What happens to the workload of the right ventricle during pulmonary embolism?
What happens to the workload of the right ventricle during pulmonary embolism?
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What compensates for the blocked lung areas during a pulmonary embolism?
What compensates for the blocked lung areas during a pulmonary embolism?
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Which of the following statements is true regarding hypocarbia?
Which of the following statements is true regarding hypocarbia?
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What is a likely consequence of inadequate gas exchange on the right side of the heart?
What is a likely consequence of inadequate gas exchange on the right side of the heart?
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Which condition is indicated by a failure to accommodate for cardiac output in the context of pulmonary embolism?
Which condition is indicated by a failure to accommodate for cardiac output in the context of pulmonary embolism?
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What is a key characteristic of the Exudative/Acute Phase in ARDS?
What is a key characteristic of the Exudative/Acute Phase in ARDS?
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During which phase of ARDS does pulmonary edema start to slowly improve?
During which phase of ARDS does pulmonary edema start to slowly improve?
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What impact is commonly associated with long-term disabilities following ARDS?
What impact is commonly associated with long-term disabilities following ARDS?
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What is a consequence of unchecked inflammation in the Exudative Phase?
What is a consequence of unchecked inflammation in the Exudative Phase?
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What happens to the lung tissue during the Fibrotic Phase?
What happens to the lung tissue during the Fibrotic Phase?
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What occurs in the response to an insult to the lungs in ARDS?
What occurs in the response to an insult to the lungs in ARDS?
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Which of the following is a severe complication that can manifest due to ARDS?
Which of the following is a severe complication that can manifest due to ARDS?
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What is a likely consequence of decreasing lung compliance?
What is a likely consequence of decreasing lung compliance?
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Which biomarker change is related to hypoxia in ARDS?
Which biomarker change is related to hypoxia in ARDS?
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In the context of ARDS, what might uncontrolled inflammation affect outside the lungs?
In the context of ARDS, what might uncontrolled inflammation affect outside the lungs?
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Study Notes
Acute Respiratory Distress Syndrome (ARDS)
- ARDS is an acute, diffuse inflammatory condition affecting the lungs, characterized by poor oxygenation and pulmonary infiltrates.
- Commonly leads to life-threatening respiratory failure with rapid onset.
- Causes include both intrapulmonary sources like lung infections and extrapulmonary factors such as sepsis, trauma, drowning, fluid overload, and toxic fumes.
Epidemiology
- Approximately 721,000 cases of ARDS are reported annually in the U.S.
- Around 25% of cases are categorized as mild; 75% develop moderate to severe disease.
- Higher severity correlates with increased mortality risk.
Definition and Diagnosis
- Defined by the Berlin Criteria, which involves timing from the insult and chest X-ray findings.
- Criteria include altered PaO2/FiO2 ratio and presence of bilateral opacities unexplained by other lung conditions.
Phases of ARDS
-
Exudative/Acute Phase (first 7 days post-insult):
- Uncontrolled inflammation damages alveolar epithelial cells and capillary endothelium.
- Leads to increased permeability and pulmonary edema, causing ventilation/perfusion (V/Q) mismatch and refractory hypoxemia.
-
Proliferative Phase (7-21 days post-insult):
- Pulmonary edema begins to improve with influx of fibroblasts.
- Damaged tissue is replaced, but lung compliance decreases, leading to atelectasis and persistent hypoxemia.
-
Fibrotic Phase (more than 21 days post-injury):
- Increased fibrosis results in decreased lung function and worsens hypoxemia.
- Airflow resistance leads to atelectasis and dead space ventilation.
Long-term Effects
- Patients may experience chronic disabilities, including anxiety, depression, poor mobility, and cognitive issues.
- Problems with breathing and memory can arise, especially following prolonged mechanical ventilation.
Conditions Increasing Risk of ARDS
- Comorbidities such as previous pulmonary embolism, cardiovascular diseases, obesity, and certain cancers elevate risk.
- Recent surgeries, particularly orthopedic and abdominal, can also contribute.
Pulmonary Embolism (PE)
- PE classification recognizes three categories: massive, submassive, and low risk based on hemodynamic stability and signs of cardiac dysfunction.
- Massive PE results in obstruction of large pulmonary arteries, causing reduced gas exchange and increased vascular resistance.
Pathophysiology of PE
- Increased alveolar dead space and bronchoconstriction due to mediators like hypoxia promote compensatory shunting in unaffected lung areas.
- This can lead to hypoxemia as regions of the lung continue to function without full capacity.
Symptoms and Diagnosis of PE
- Most common symptoms include dyspnea, tachycardia, anxiety, cough, and pleuritic chest pain.
- Diagnostic tests: ABG, chest X-ray, echocardiogram, D-dimer levels, and possible EKG changes.
Prevention and Treatment
- Prevention strategies include the use of low molecular weight heparin (LMWH) and pneumatic compression devices.
- Treatment focuses on preventing recurrence, promoting gas exchange, and managing complications, including thrombolytic therapy for clot dissolution.
Nursing Management
- Active and passive range of motion exercises to improve mobility.
- Adequate hydration and early ambulation are crucial for recovery and prevention of further complications.
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Description
This quiz delves into Acute Respiratory Distress Syndrome (ARDS), an acute lung condition that leads to significant respiratory failure. It outlines the epidemiology, diagnostic criteria, and phases of ARDS, highlighting its causes and the associated mortality rates. Test your knowledge on this critical respiratory condition.