Acute Respiratory Distress Syndrome (ARDS) Overview
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Questions and Answers

What is the primary characteristic of ARDS?

  • Gradual onset of symptoms
  • Acute, diffuse inflammatory injury to the lungs (correct)
  • Chronic lung disease
  • Minor respiratory issues
  • Which of the following factors is a known cause of ARDS?

  • Healthy diet
  • Fluid overload (correct)
  • Regular exercise
  • Good sleep patterns
  • What percentage of ARDS patients typically experience mild disease?

  • 10%
  • 50%
  • 75%
  • 25% (correct)
  • What is the relationship between the severity of ARDS and mortality rates?

    <p>Higher severity results in higher mortality rates</p> Signup and view all the answers

    Which of the following is not an identified source of ARDS?

    <p>Asthma</p> Signup and view all the answers

    Which symptom is NOT commonly associated with pulmonary embolism (PE)?

    <p>Sore throat</p> Signup and view all the answers

    Which laboratory test is primarily used to diagnose pulmonary embolism?

    <p>D-dimer</p> Signup and view all the answers

    What is a non-pharmacological method mentioned for the prevention of pulmonary embolism?

    <p>Pneumatic compression</p> Signup and view all the answers

    Which imaging technique is used to visualize the size and location of a pulmonary embolism?

    <p>Echocardiogram</p> Signup and view all the answers

    Which of the following statements about the treatment of pulmonary embolism is incorrect?

    <p>Anticoagulation is not necessary.</p> Signup and view all the answers

    Which of the following conditions is a known risk factor for developing venous stasis?

    <p>Atrial Fibrillation</p> Signup and view all the answers

    What is a significant cause of injury to the vascular endothelium?

    <p>Trauma or Infection</p> Signup and view all the answers

    Which cancer types are linked to an increased risk of thrombosis?

    <p>Ovarian Cancer and Stomach Cancer</p> Signup and view all the answers

    What is a primary characteristic of a massive pulmonary embolism (PE)?

    <p>Hypotensive state</p> Signup and view all the answers

    Which of the following describes a low-risk pulmonary embolism classification?

    <p>No underlying cardiovascular disease</p> Signup and view all the answers

    Which of the following medications is often associated with a higher risk of thrombosis?

    <p>Birth Control Pills</p> Signup and view all the answers

    What physiological change is associated with hypercoagulability?

    <p>Increased likelihood of clot formation</p> Signup and view all the answers

    Which of the following statements about immobility is true?

    <p>It decreases blood flow leading to venous stasis.</p> Signup and view all the answers

    What effect does an increase in alveolar dead space have on gas exchange?

    <p>It reduces gas exchange capacity.</p> Signup and view all the answers

    What physiological response is triggered due to hypoxia in the lungs?

    <p>Increased airway resistance</p> Signup and view all the answers

    What is the main cause of shunting in the lungs during pulmonary embolism?

    <p>Inadequate oxygenation in perfused regions</p> Signup and view all the answers

    What happens to the workload of the right ventricle during pulmonary embolism?

    <p>It increases due to increased vascular resistance.</p> Signup and view all the answers

    What compensates for the blocked lung areas during a pulmonary embolism?

    <p>Increased perfusion to unaffected areas</p> Signup and view all the answers

    Which of the following statements is true regarding hypocarbia?

    <p>It can trigger local airway constriction.</p> Signup and view all the answers

    What is a likely consequence of inadequate gas exchange on the right side of the heart?

    <p>Increased flow of deoxygenated blood returning to the heart.</p> Signup and view all the answers

    Which condition is indicated by a failure to accommodate for cardiac output in the context of pulmonary embolism?

    <p>Compensatory shunting</p> Signup and view all the answers

    What is a key characteristic of the Exudative/Acute Phase in ARDS?

    <p>Damage to capillary endothelium</p> Signup and view all the answers

    During which phase of ARDS does pulmonary edema start to slowly improve?

    <p>Proliferative Phase</p> Signup and view all the answers

    What impact is commonly associated with long-term disabilities following ARDS?

    <p>Difficulty in breathing</p> Signup and view all the answers

    What is a consequence of unchecked inflammation in the Exudative Phase?

    <p>Decreased oxygenation due to V/Q mismatch</p> Signup and view all the answers

    What happens to the lung tissue during the Fibrotic Phase?

    <p>Increased fibrosis and decreased elasticity</p> Signup and view all the answers

    What occurs in the response to an insult to the lungs in ARDS?

    <p>Platelet activation leads to shock</p> Signup and view all the answers

    Which of the following is a severe complication that can manifest due to ARDS?

    <p>Refractory hypoxemia</p> Signup and view all the answers

    What is a likely consequence of decreasing lung compliance?

    <p>Atelectasis</p> Signup and view all the answers

    Which biomarker change is related to hypoxia in ARDS?

    <p>Diminished surfactant production</p> Signup and view all the answers

    In the context of ARDS, what might uncontrolled inflammation affect outside the lungs?

    <p>Promote immune responses in distant organs</p> Signup and view all the answers

    Study Notes

    Acute Respiratory Distress Syndrome (ARDS)

    • ARDS is an acute, diffuse inflammatory condition affecting the lungs, characterized by poor oxygenation and pulmonary infiltrates.
    • Commonly leads to life-threatening respiratory failure with rapid onset.
    • Causes include both intrapulmonary sources like lung infections and extrapulmonary factors such as sepsis, trauma, drowning, fluid overload, and toxic fumes.

    Epidemiology

    • Approximately 721,000 cases of ARDS are reported annually in the U.S.
    • Around 25% of cases are categorized as mild; 75% develop moderate to severe disease.
    • Higher severity correlates with increased mortality risk.

    Definition and Diagnosis

    • Defined by the Berlin Criteria, which involves timing from the insult and chest X-ray findings.
    • Criteria include altered PaO2/FiO2 ratio and presence of bilateral opacities unexplained by other lung conditions.

    Phases of ARDS

    • Exudative/Acute Phase (first 7 days post-insult):

      • Uncontrolled inflammation damages alveolar epithelial cells and capillary endothelium.
      • Leads to increased permeability and pulmonary edema, causing ventilation/perfusion (V/Q) mismatch and refractory hypoxemia.
    • Proliferative Phase (7-21 days post-insult):

      • Pulmonary edema begins to improve with influx of fibroblasts.
      • Damaged tissue is replaced, but lung compliance decreases, leading to atelectasis and persistent hypoxemia.
    • Fibrotic Phase (more than 21 days post-injury):

      • Increased fibrosis results in decreased lung function and worsens hypoxemia.
      • Airflow resistance leads to atelectasis and dead space ventilation.

    Long-term Effects

    • Patients may experience chronic disabilities, including anxiety, depression, poor mobility, and cognitive issues.
    • Problems with breathing and memory can arise, especially following prolonged mechanical ventilation.

    Conditions Increasing Risk of ARDS

    • Comorbidities such as previous pulmonary embolism, cardiovascular diseases, obesity, and certain cancers elevate risk.
    • Recent surgeries, particularly orthopedic and abdominal, can also contribute.

    Pulmonary Embolism (PE)

    • PE classification recognizes three categories: massive, submassive, and low risk based on hemodynamic stability and signs of cardiac dysfunction.
    • Massive PE results in obstruction of large pulmonary arteries, causing reduced gas exchange and increased vascular resistance.

    Pathophysiology of PE

    • Increased alveolar dead space and bronchoconstriction due to mediators like hypoxia promote compensatory shunting in unaffected lung areas.
    • This can lead to hypoxemia as regions of the lung continue to function without full capacity.

    Symptoms and Diagnosis of PE

    • Most common symptoms include dyspnea, tachycardia, anxiety, cough, and pleuritic chest pain.
    • Diagnostic tests: ABG, chest X-ray, echocardiogram, D-dimer levels, and possible EKG changes.

    Prevention and Treatment

    • Prevention strategies include the use of low molecular weight heparin (LMWH) and pneumatic compression devices.
    • Treatment focuses on preventing recurrence, promoting gas exchange, and managing complications, including thrombolytic therapy for clot dissolution.

    Nursing Management

    • Active and passive range of motion exercises to improve mobility.
    • Adequate hydration and early ambulation are crucial for recovery and prevention of further complications.

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    Description

    This quiz delves into Acute Respiratory Distress Syndrome (ARDS), an acute lung condition that leads to significant respiratory failure. It outlines the epidemiology, diagnostic criteria, and phases of ARDS, highlighting its causes and the associated mortality rates. Test your knowledge on this critical respiratory condition.

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