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Acute Interstitial Nephritis

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Questions and Answers

What is a common feature of acute interstitial nephritis (AIN)?

Mild renal impairment (correct)

Peripheral eosinophilia

Severe hypertension

High fever

Which of the following is a possible cause of acute interstitial nephritis?

Oral contraceptives

Antacids

NSAIDS (correct)

Antihistamines

What is the recommended treatment for acute interstitial nephritis?

Administer high-dose aspirin

Stop/treat causative agent (correct)

Start angiotensin-converting enzyme (ACE) inhibitors

Initiate dialysis

What type of immune reaction is associated with acute interstitial nephritis?

<p>Inflammatory cell infiltrate in the interstitium</p> Signup and view all the answers

What is a key factor for a good prognosis in acute interstitial nephritis?

<p>Early detection</p> Signup and view all the answers

Study Notes

Acute Interstitial Nephritis (AIN)

A common feature of AIN is a rapid decline in kidney function.

Causes of AIN

A possible cause of AIN is an allergic reaction to certain medications, including antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDs), and proton pump inhibitors.

Treatment of AIN

The recommended treatment for AIN involves removing the offending agent, such as stopping the causative medication.

Immune Reaction in AIN

AIN is associated with a type IV hypersensitivity immune reaction, which involves the activation of T cells and macrophages.

Prognosis of AIN

A key factor for a good prognosis in AIN is prompt recognition and treatment, which can lead to recovery of kidney function.

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Description

Test your knowledge of Acute Interstitial Nephritis (AIN) and its causes, including drug reactions, infections, and autoimmune disorders. Explore the clinical presentation and evaluation of AIN, including the importance of taking a comprehensive drug history.