Lecture 5
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Questions and Answers

What is inflammation a response to?

  • Infectious agents
  • Vascularized tissue
  • Scarring
  • Necrotic cells and tissues resulting from the original insult (correct)
  • What characterizes acute inflammation?

  • Scarring and vascular proliferation
  • Predominantly neutrophilic accumulation, fluid & plasma protein exudation (correct)
  • Influx of lymphocytes and macrophages
  • Loss of function
  • What is the duration of chronic inflammation?

  • Years to decades
  • Days to years (correct)
  • Lifetime
  • A few minutes to few days
  • What is the fifth classic cardinal sign of inflammation?

    <p>Functio lease (Loss of function) (B)</p> Signup and view all the answers

    What is the result of hyperemia?

    <p>Increased blood flow to the injured area (D)</p> Signup and view all the answers

    What happens as blood flow increases in capillaries?

    <p>Capillary hydrostatic pressure rises (A)</p> Signup and view all the answers

    What is the primary reason for fluid leading to pain in inflammation?

    <p>Increased permeability at postcapillary venules (A)</p> Signup and view all the answers

    What is the result of blood volume decreasing and becoming viscous?

    <p>Aggregation of RBCs (D)</p> Signup and view all the answers

    Which of the following is an example of a physical agent that can cause inflammation?

    <p>Thermal injury (A)</p> Signup and view all the answers

    What is the primary function of WBCs in inflammation?

    <p>To clear the invaders and start digesting the necrotic tissue (C)</p> Signup and view all the answers

    What is the term for inflammatory diseases caused by immune reactions or hypersensitivity reactions?

    <p>Immune-mediated inflammatory diseases (D)</p> Signup and view all the answers

    What is the result of increased vascular permeability in acute inflammation?

    <p>Extravascular leakage of plasma proteins (D)</p> Signup and view all the answers

    What is the primary cell involved in acute inflammation?

    <p>Neutrophil (C)</p> Signup and view all the answers

    What is the term for the accumulation of fluid in the extra-vascular space?

    <p>Edema (D)</p> Signup and view all the answers

    What is the main difference between transudate and exudate?

    <p>Exudate is rich in proteins, while transudate has little proteins (D)</p> Signup and view all the answers

    What is the primary cause of transudate formation?

    <p>Increased hydrostatic pressure in the capillaries (B)</p> Signup and view all the answers

    What is the location where endothelial cell contraction is most pronounced during acute inflammation?

    <p>Post-capillary venules (C)</p> Signup and view all the answers

    What is the result of increased osmotic pressure in the interstitial tissues?

    <p>Outflow of water and ions into the extravascular tissues (C)</p> Signup and view all the answers

    What is the main characteristic of ultrafiltrate of plasma?

    <p>Low protein content (A)</p> Signup and view all the answers

    What is the primary mechanism of increasing permeability of small vessels during inflammation due to chemical mediators?

    <p>Formation of gaps between endothelial cells (C)</p> Signup and view all the answers

    What is the response of lymphatics during inflammation?

    <p>Lymph flow is increased, and drains edema fluid (A)</p> Signup and view all the answers

    What is the sequence of events in the recruitment of leukocytes during inflammation?

    <p>Margination, rolling, firm adhesions, and pavementing (D)</p> Signup and view all the answers

    What is the result of increased vascular permeability during inflammation?

    <p>Increased interstitial osmotic pressure (A)</p> Signup and view all the answers

    What is the characteristic of exudate?

    <p>High protein content and specific gravity &gt;1.020 (D)</p> Signup and view all the answers

    What is the primary mechanism of increasing permeability of small vessels during inflammation?

    <p>All of the above (D)</p> Signup and view all the answers

    What is the effect of histamine on endothelial cells during inflammation?

    <p>Formation of gaps between endothelial cells (D)</p> Signup and view all the answers

    What is the primary function of lymphatics during inflammation?

    <p>Draining edema fluid (D)</p> Signup and view all the answers

    What is the sequence of events in the recruitment of leukocytes during inflammation?

    <p>Margination, rolling, and firm adhesions (B)</p> Signup and view all the answers

    What is the characteristic of ultrafiltrate of plasma?

    <p>Low protein content (D)</p> Signup and view all the answers

    What is the result of increased vascular permeability during inflammation?

    <p>Formation of exudate (D)</p> Signup and view all the answers

    What is the primary event in the increased permeability of small vessels during inflammation?

    <p>Formation of gaps between endothelial cells (A)</p> Signup and view all the answers

    What is the result of increased interstitial osmotic pressure?

    <p>Formation of exudate (B)</p> Signup and view all the answers

    What is the primary function of leukocyte activation during inflammation?

    <p>To fight off pathogens (B)</p> Signup and view all the answers

    What is the characteristic of exudate?

    <p>High protein content (B)</p> Signup and view all the answers

    What is the primary reason for the increased lymph flow during inflammation?

    <p>To drain edema fluid (C)</p> Signup and view all the answers

    Which of the following mechanisms is responsible for the increased permeability of small vessels during inflammation due to the effect of chemical mediators?

    <p>Formation of gaps between endothelial cells (C)</p> Signup and view all the answers

    What is the characteristic of exudate that distinguishes it from ultrafiltrate of plasma?

    <p>High protein content and specific gravity &gt;1.020 (A)</p> Signup and view all the answers

    What is the sequence of events in the recruitment of leukocytes to the extravascular space during inflammation?

    <p>Margination, rolling, firm adhesions, and pavementing (A)</p> Signup and view all the answers

    What is the primary function of leukocyte activation during inflammation?

    <p>To phagocytose foreign particles and bacteria (C)</p> Signup and view all the answers

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