10 Questions
What is the Oxygen Enhancement Ratio (OER) of X-rays?
2.5
When must oxygen be present for the oxygen effect to be observed?
During or within microseconds after radiation exposure
How long after irradiation can oxygen still act to sensitize cells?
Up to 5 milliseconds after irradiation
At what level do free radicals act to cause radiation damage?
At the level of free radicals
Which phase of the cell cycle has a lower OER?
G1
What is the approximate OER for neutrons?
1.6
Why does the OER decrease at low doses for rapidly growing cells?
Because G1 cells are more radiosensitive
What is the range of oxygen tension between different tissues?
1-100 mm Hg
What type of hypoxia results from the limited diffusion distance of oxygen through tissue?
Chronic hypoxia
What is the minimum amount of oxygen required to produce the dramatic oxygen effect with X-rays?
Very small amounts of oxygen
Learn about acute hypoxia, a temporary condition in tumors caused by the malfunctioning of blood vessels. Understand how it leads to intermittent hypoxia and reoxygenation. Test your knowledge of this important concept in cancer biology.
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