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Acute Hypoxia in Tumors

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Questions and Answers

What is the Oxygen Enhancement Ratio (OER) of X-rays?

4.0

1.6

3.0

2.5 (correct)

When must oxygen be present for the oxygen effect to be observed?

During or within microseconds after radiation exposure (correct)

Only after radiation exposure is complete

At any time after radiation exposure

Only during radiation exposure

How long after irradiation can oxygen still act to sensitize cells?

Up to 1 second after irradiation

Up to 5 milliseconds after irradiation (correct)

Only during radiation exposure

Up to 1 millisecond after irradiation

At what level do free radicals act to cause radiation damage?

At the level of free radicals Signup and view all the answers

Which phase of the cell cycle has a lower OER?

G1 Signup and view all the answers

What is the approximate OER for neutrons?

1.6 Signup and view all the answers

Why does the OER decrease at low doses for rapidly growing cells?

Because G1 cells are more radiosensitive Signup and view all the answers

What is the range of oxygen tension between different tissues?

1-100 mm Hg Signup and view all the answers

What type of hypoxia results from the limited diffusion distance of oxygen through tissue?

Chronic hypoxia Signup and view all the answers

What is the minimum amount of oxygen required to produce the dramatic oxygen effect with X-rays?

Very small amounts of oxygen Signup and view all the answers