Acute Glomerulonephritis Overview
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Acute Glomerulonephritis Overview

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Questions and Answers

What usually precedes the onset of glomerulonephritis?

Group A beta-hemolytic Streptococcal infections of the throat.

What is acute glomerulonephritis?

It is the inflammation of the glomeruli of the kidneys.

What are common clinical manifestations of acute glomerulonephritis? (Select all that apply)

  • Hyperglycemia
  • Reduced urine volume (correct)
  • Proteinuria (correct)
  • Hematuria (correct)
  • Chronic nephritis is always symptomatic.

    <p>False</p> Signup and view all the answers

    Which of the following may lead to acute glomerulonephritis? (Select all that apply)

    <p>Mumps</p> Signup and view all the answers

    One of the primary presenting features of acute glomerulonephritis is __________.

    <p>hematuria</p> Signup and view all the answers

    What happens to BUN and serum creatinine levels as urine output drops in acute glomerulonephritis?

    <p>They may rise.</p> Signup and view all the answers

    Match the following terms with their definitions:

    <p>Hematuria = Blood in the urine Oliguria = Reduced urine volume Proteinuria = Presence of protein in urine Azotemia = Increased levels of nitrogenous wastes in blood</p> Signup and view all the answers

    Hypertension is noted in 75% of cases of acute glomerulonephritis.

    <p>True</p> Signup and view all the answers

    Study Notes

    Acute Glomerulonephritis

    • Inflammation of the glomeruli in the kidneys.
    • Occurs 2-3 weeks after streptococcal infection of the throat.
    • Causes:
      • Group A beta-hemolytic Streptococcal infections.
      • Bacterial endocarditis.
      • Acute viral infections.
      • Hepatitis B.
      • HIV infection.
      • Schistosomiasis.
      • Leishmaniasis.
      • Immunologic abnormalities.
      • Free radicals.
      • Vascular disorders.
      • Medications, foreign serum, toxins.
    • Pathophysiology
      • Antigen-antibody complexes form in the glomeruli.
      • Increased production of epithelial cells lining the glomerulus.
      • Leukocytes infiltrate the glomerulus.
      • Thickening of the glomerular filtration membrane.
      • Scarring and loss of the glomerular filtration membrane.
      • Decreased glomerular filtration rate.
    • Clinical Manifestations:
      • Hematuria (blood in the urine).
      • Proteinuria (protein in the urine).
      • Reduced urine volume (oliguria).
      • Elevated BUN and serum creatinine levels.
      • Generalized edema.
      • Hypertension.
      • Azotemia.
      • Protein casts in the urine.
      • Headaches.
      • Malaise.
      • Flank pain.
      • Elderly patients may experience circulatory overload with dyspnea, engorged neck veins, cardiomegaly and pulmonary edema.
    • Diagnostic Measures:
      • History, signs, and symptoms.

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    Description

    This quiz covers the causes, pathophysiology, and clinical manifestations of Acute Glomerulonephritis. It specifically discusses the role of infections and immunologic factors in the condition. Test your understanding of the kidney's glomeruli and their impact on health.

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