24 Questions
What is excitability in the context of excitable membranes?
The ability of tissues to generate electrical signals
Which of the following tissues are considered excitable tissues?
Nerves and Muscles
What is the typical resting membrane potential (RMP) value for skeletal muscles?
-90 mV
What contributes to the resting membrane potential of excitable tissues?
Selective permeability of cell membrane
What does it mean when the inner surface of a nerve fiber is negatively charged during rest?
It is polarized
What role do passive (non-gated) channels play in the resting membrane potential?
Responsible for maintaining the RMP
During Repolarization, the M gate of voltage-gated Na channels is:
Opened
At rest, the n-gate of voltage-gated K channels is:
Closed
What is the main cause of the Resting Membrane Potential (RMP)?
Diffusion of K+ ions from inside to outside the cell
What type of potential results from stimulation by an ineffective or subminimal stimulus?
Graded potential
What is the significance of the Sodium & Potassium Pump (Na-K pump)?
Electrogenic - pumps 2 Na+ outside in exchange for 3 K+ inside
Where does the receptor potential typically occur?
In the beginning of sensory nerves
What type of channels are responsible for Action Potential?
Voltage-activated channels
What happens to the h gate of voltage-gated Na channels during Depolarization?
Opened
Which type of potential propagates along nerve fibers without decrement and produces a response?
Action potential
What happens during Rapid Depolarization in an Action Potential?
Massive Na+ influx leading to membrane potential becoming positive
What occurs during Repolarization phase of an Action Potential?
K+ efflux through voltage-activated K+ channels
What initiates the opening of Voltage-Activated Na channels in Slow Depolarization?
Increase in membrane permeability to Na+ ions
What is the role of the Na-K pump?
Transport sodium out and potassium into the cell
What is the latent period in the monophasic action potential?
Time between application of stimulus and appearance of response
What is the primary cause of negative after potential in nerve cells?
Slow potassium efflux
Which ion is transported out of the cell by the Na-K pump?
Sodium
Where is the reference electrode typically placed in recording action potentials?
Outside the cell
What is the main function of the M gate (activation gate) of voltage-gated Na channels?
Cover extracellular surface
Test your knowledge on the components of action potential and the redistribution of ions during the process. Includes topics like K+ efflux, RMP restoration, delayed closure of K channels, and the role of the Na-K pump.
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