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Questions and Answers
What is the molecular weight of actin?
What is the molecular weight of actin?
- 40kDa (correct)
- 30kDa
- 60kDa
- 50kDa
During actin polymerization, what is the critical concentration (Cc) defined as?
During actin polymerization, what is the critical concentration (Cc) defined as?
- The concentration of ATP required for hydrolysis
- The concentration at which the rate of subunit addition and loss are equal (correct)
- The concentration of G-actin needed for nucleation
- The concentration of Mg2+ ions required for filament formation
What provides the energy required for adding actin subunits onto the filament during elongation phase?
What provides the energy required for adding actin subunits onto the filament during elongation phase?
- Mg2+ ion
- Pi
- ADP
- ATP (correct)
How many protofilaments are alpha and beta tubulin molecules arranged in to form tubules?
How many protofilaments are alpha and beta tubulin molecules arranged in to form tubules?
What type of nucleotide provides energy for dimer binding in tubulin polymerization?
What type of nucleotide provides energy for dimer binding in tubulin polymerization?
Actin polymerization occurs in three phases: nucleation, elongation, and steady phase.
Actin polymerization occurs in three phases: nucleation, elongation, and steady phase.
During the nucleation phase, G-actin subunits collide with each other and weakly associate to form oligomers.
During the nucleation phase, G-actin subunits collide with each other and weakly associate to form oligomers.
The critical concentration (Cc) is higher when there is a higher concentration of actin subunits and more frequent collisions.
The critical concentration (Cc) is higher when there is a higher concentration of actin subunits and more frequent collisions.
Tubulin forms heterodimers composed of alpha and beta tubulin molecules.
Tubulin forms heterodimers composed of alpha and beta tubulin molecules.
Tubulin dimers stick together with the use of nucleotide ATP, which provides energy for the polymerization process.
Tubulin dimers stick together with the use of nucleotide ATP, which provides energy for the polymerization process.
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