Actin Polymerization and Filament Structure

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30 Questions

Which of the following is a function of the cytoskeleton?

Cell shape maintenance

What are the three types of protein filaments that make up the cytoskeleton?

Intermediate, microtubules, actin

What is the main role of actin filaments in the cell?

Cell shape and movement

What is the process of actin filaments forming long chains called?

Polymerization

Which component of the cytoskeleton determines cellular organization and polarity?

Actin filaments

What are the main functions of the cytoskeleton?

Cell shape maintenance and cell movement

Which protein is responsible for causing motion inside cells in association with parts of the cytoskeleton?

Myosin

What is the function of actin-associated motor proteins?

Cargo transportation

Which type of myosin is involved in muscle contraction in most animal cells?

Myosin II

What is the role of actin filaments and myosin (II) during cytokinesis?

They form contractile structures

Which motor protein has a tail that can bind to transporting vesicles?

Myosin I

What is the main function of ATP in actin-dependent motor proteins?

Mechanical energy

Which type of actin crosslinker forms more rigid bundles?

Filamin

What happens when ATP is hydrolyzed to ADP in actin filaments?

Reduces strength of binding between monomers

Which protein inhibits nucleation in actin polymerization?

Profilin

What type of actin crosslinker forms 3D gel-like networks?

Filamin

Which end of actin filaments is usually shorter than microtubules?

(-)-End

Which process is NOT known to be essential for cell movement involving actin?

All of the above processes are essential for cell movement

Which of the following is NOT a function of the cytoskeleton?

Directing intracellular transport

What is the function of actin filaments in a cell?

Determining the shape of a cell and enabling cell locomotion

Which type of cytoskeletal filament is made up of elongated and fibrous subunits?

Intermediate filaments

What is the main function of microtubules in a cell?

Directing intracellular transport

Which type of cytoskeletal filament is involved in maintaining mechanical integrity?

Actin filaments

What is the function of adherens junctions in a cell?

Occurring at cell-cell junctions

Which proteins interact with actin filaments to help move vesicles and organelles in the cell periphery?

Mitochondria

What is the main function of the sarcomere in muscle cells?

To contract the muscle

What molecular events are involved in muscle contraction?

Crossbridge cycling

What is the role of tropomyosin and troponins in striated muscle?

To block the binding of myosin to actin

What triggers the release of calcium ions in muscle contraction?

Depolarization of myofibrils

Which drug can be used to stain actin filaments and block their depolymerization?

Phalloidin

Test your knowledge on actin polymerization and the structure of actin filaments with this quiz. Learn about nucleation, steady state, ATP elongation, and more.

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