Acknowledgments in Medical Research
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Questions and Answers

Which individual is acknowledged for their guidance and encouragement?

  • Dr. Karthik Sasalu
  • Dr. Rakesh SP
  • Dr. Malthesha M.K. (correct)
  • Dr. Sanjay Kumar

What role did the Superintendent of Chigateri General Hospital play in the study?

  • Reviewed the dissertation
  • Conducted the study
  • Provided necessary information (correct)
  • Assisted in patient care

Which group of individuals received a heartful thanks for their cooperation in the study?

  • Post-graduate colleagues
  • Family members
  • Senior doctors
  • Patients (correct)

Which individual is listed first among the author’s family members for support?

<p>Father Manjunath B C (B)</p> Signup and view all the answers

Who assisted in the computerized layout of the dissertation?

<p>Mr. Bharath Kumar D.G. (B)</p> Signup and view all the answers

What is the full form of the abbreviation 'HbA1c'?

<p>Hemoglobin A1c (C)</p> Signup and view all the answers

Which term refers to the study known as the United Kingdom Prospective Diabetes Study?

<p>UKPDS (A)</p> Signup and view all the answers

What does the abbreviation 'T2DM' stand for?

<p>Type 2 diabetes mellitus (B)</p> Signup and view all the answers

Which abbreviation represents 'Low-density lipoprotein'?

<p>LDL (C)</p> Signup and view all the answers

What does 'SMBG' stand for in diabetes management?

<p>Self-monitoring of blood glucose (B)</p> Signup and view all the answers

Which of the following abbreviations refers to 'Diabetes Control and Complications Trial'?

<p>DCCT (A)</p> Signup and view all the answers

The abbreviation 'PAI-1' refers to what?

<p>Plasminogen Activator Inhibitor-1 (B)</p> Signup and view all the answers

What does the abbreviation 'ACE2' represent?

<p>Angiotensin-converting enzyme 2 (D)</p> Signup and view all the answers

What section of the document would you refer to for the methodology used in the study?

<p>Section 4: Methodology (B)</p> Signup and view all the answers

In which section would you find the demographic and basic clinical characteristics of participants?

<p>List of Tables, Table 1: Demographic and Basic Clinical Characteristics (C)</p> Signup and view all the answers

Which annexure would provide insight into the patient consent process?

<p>Annexure II: Patient Consent Form (C)</p> Signup and view all the answers

Where would you find the results of lipid profiles in the study?

<p>Section 5: Results, Table 2 (A)</p> Signup and view all the answers

Which section concludes the document by summarizing findings?

<p>Section 7: Conclusion (B)</p> Signup and view all the answers

What would you expect to find in Annexure III?

<p>Approval letter from the ethical committee (C)</p> Signup and view all the answers

Which element is NOT listed as a table in the document?

<p>Patient Demographics (A)</p> Signup and view all the answers

What is the purpose of Section 8 in the document?

<p>To summarize and highlight key findings (A)</p> Signup and view all the answers

What was the primary objective of the study?

<p>To investigate the association between platelet indices and diabetic dyslipidemia (A)</p> Signup and view all the answers

How many participants in the study had dyslipidemia?

<p>26 (D)</p> Signup and view all the answers

What statistical parameter was used to compare the two groups in the study?

<p>Statistical significance (p-value) (C)</p> Signup and view all the answers

Which clinical parameter was notably higher in participants with dyslipidemia?

<p>MPV levels (D)</p> Signup and view all the answers

What condition is closely associated with dyslipidemia as noted in the study?

<p>Type 2 diabetes mellitus (D)</p> Signup and view all the answers

Which of the following is NOT mentioned as a parameter evaluated in relation to dyslipidemia?

<p>Bone density (D)</p> Signup and view all the answers

What was the sample size of the study participants?

<p>72 (C)</p> Signup and view all the answers

What type of study design was used for this research?

<p>Cross-sectional study (C)</p> Signup and view all the answers

Who is the lead author of the dissertation?

<p>Dr.HARSHITH M.M. (A)</p> Signup and view all the answers

What is the focus of the study in the dissertation?

<p>Correlation between Type 2 diabetic dyslipidemia and platelet indices (C)</p> Signup and view all the answers

In which year was the dissertation submitted?

<p>2024 (B)</p> Signup and view all the answers

Who guided the author of the dissertation?

<p>Dr.U.R.RAAJU (D)</p> Signup and view all the answers

What position does Dr.HARISHA E.J. hold?

<p>Head of Department of Medicine (D)</p> Signup and view all the answers

Which college is associated with the dissertation?

<p>J.J.M Medical College (D)</p> Signup and view all the answers

What degree is the dissertation submitted for?

<p>Doctor of Medicine (B)</p> Signup and view all the answers

Which of the following individuals is NOT mentioned in the acknowledgement section?

<p>Dr.B.G.RENUKA (C)</p> Signup and view all the answers

Flashcards

What is the main research objective of the study?

The study aims to explore the connection between dyslipidemia (abnormal levels of fats and cholesterol) and specific platelet indices (MPV and P-LCR) in patients with type 2 diabetes.

What does MPV stand for?

Mean Platelet Volume (MPV) is a measurement indicating the average size of platelets, which are involved in blood clotting.

What does P-LCR stand for?

Platelet-Large Cell Ratio (P-LCR) is a measurement reflecting the proportion of large-sized platelets in the blood.

What is type 2 diabetes?

Type 2 diabetes is a metabolic condition where the body does not effectively use insulin to regulate blood sugar levels.

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What is dyslipidemia?

Dyslipidemia is a condition characterized by abnormal levels of lipids (fats and cholesterol) in the blood, potentially leading to cardiovascular health issues.

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What are platelets?

Platelets are small cells in the blood responsible for clotting, preventing excessive bleeding.

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Where is this research taking place?

This research is being conducted at the JJM Medical College in Davangere, Karnataka, India.

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Who is the author of this dissertation?

Dr. Harshit M.M. is the author of the dissertation, supervised by Dr. U.R. Raju.

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Cardiologist

A medical doctor specializing in the diagnosis and treatment of heart conditions.

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Endocrinologist

A medical doctor specializing in the diagnosis and treatment of hormone disorders.

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Nephrologist

A medical doctor specializing in the diagnosis and treatment of kidney diseases.

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Physician (M.D.)

A medical doctor specializing in the diagnosis and treatment of diseases related to the internal organs.

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Specialist

A medical doctor who has completed additional training in a specific specialty.

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What is CHD?

Coronary heart disease (CHD) is a common condition where the arteries that supply blood to the heart become narrowed and hardened, reducing blood flow and increasing the risk of heart attacks and other cardiovascular problems.

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What is HbA1c?

Glycated hemoglobin (HbA1c) is a blood test measuring the average blood sugar level over the past 2-3 months. It helps monitor long-term blood sugar control in people with diabetes.

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What is LDL?

Low-density lipoprotein (LDL) is a type of cholesterol often referred to as 'bad' cholesterol because high levels contribute to plaque buildup in arteries, increasing the risk of heart disease.

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What is HDL?

High-density lipoprotein (HDL) is a type of cholesterol often referred to as 'good' cholesterol because it helps remove excess cholesterol from arteries, reducing the risk of heart disease.

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What is Type 2 Diabetes (T2DM)?

Type 2 diabetes is a chronic condition where the body doesn't use insulin properly, leading to high blood sugar levels. It often develops in adulthood and is linked to lifestyle factors.

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What is IGT?

Impaired glucose tolerance (IGT) is a condition where blood sugar levels rise higher than normal after eating but not as high as in diabetes. It's a precursor to type 2 diabetes.

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What is BMI?

Body mass index (BMI) is a measure used to assess body fat based on height and weight. A high BMI is linked to increased risk of various health problems, including diabetes and heart disease.

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What is the ADVANCE study?

The Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation (ADVANCE) study was a large, international clinical trial that compared different diabetes medications and lifestyle interventions for managing type 2 diabetes and reducing cardiovascular risk.

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What is MPV?

The average size of platelets in the blood, measured in femtoliters (fL).

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What is P-LCR?

The proportion of large-sized platelets in the blood, indicating platelet activation and potentially increased clotting risk.

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What is methodology?

The study of how to collect, analyze, and interpret data to answer research questions.

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What is discussion?

The process of carefully examining and discussing the results of a research study, comparing them to previous research, and interpreting their significance.

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What is conclusion?

A concise summary of the main points, findings, and implications of a study.

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What is a cross-sectional study?

A study design where data is collected at a single point in time, offering a snapshot of characteristics and relationships.

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What is mean platelet volume (MPV)?

A measurement reflecting the average size of platelets, which are involved in blood clotting.

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What is platelet-large cell ratio (P-LCR)?

A measurement indicating the proportion of large-sized platelets in the blood.

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What is the main study objective?

The research aims to study the relationship between platelet indices (MPV and P-LCR) and dyslipidemia in patients with type 2 diabetes.

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What does the 'lipid profile' section of the study involve?

This aspect of the study looks at how many participants have different lipid levels (cholesterol, triglycerides, etc.) in their blood.

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Why are participants categorized into groups based on dyslipidemia?

This part of the study focuses on comparing characteristics and health indicators between participants with and without dyslipidemia.

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Study Notes

Dissertation Title and Details

  • Title: "A STUDY OF CORRELATION BETWEEN TYPE 2 DIABETIC DYSLIPIDEMIA WITH PLATELET INDICES-MPV, P-LCR”
  • Candidate: Dr. HARSHITH M.
  • Submitted to: Rajiv Gandhi University of Health Sciences, Karnataka, Bangalore
  • Under the guidance of: Dr. U.R. RAAJU. M.D. (Associate Professor)
  • Department: Department of General Medicine
  • College: J.J.M Medical College
  • Location: Davangere - 577 004
  • Year: 2024

Declaration by the Candidate

  • The candidate declares the dissertation is original research work

Certificate by the Guide

  • The guide confirms the dissertation is original research work by the candidate

Endorsement by the HOD, Principal/Head of the Institution

  • The HOD and Principal endorse the dissertation is original research work and complies with all requirements
  • The candidate agrees to the rights of Rajiv Gandhi University of Health Sciences, Karnataka to preserve, use, and disseminate the dissertation in print or electronic format for academic or research purpose

Acknowledgement

  • Expresses gratitude to all those who helped during the research
  • Specifically thanks their guide, Dr. U.R. RAAJU
  • Acknowledges the support of other professors, and the college/hospital staff
  • Thanks their parents and family members

List of Abbreviations

  • This section includes a list of abbreviations used in the dissertation with their full forms.

Table of Contents

  • Provides a detailed overview of the content of the dissertation with page numbers.

List of Tables

  • This section lists the tables with relevant page numbers

List of Figures

  • This section lists the figures with relevant page numbers

Graphs

  • This section lists the graphs with relevant page numbers

Abstract

  • The study investigated the association between platelet indices (MPV and P-LCR) and diabetic dyslipidemia in patients with type 2 diabetes.
  • Participants with dyslipidemia had significantly higher levels of MPV and P-LCR compared to those without dyslipidemia.
  • They also had poorer glycemic control (higher HbA1c levels), worse lipid profiles (higher total cholesterol, LDL cholesterol; lower HDL cholesterol) and higher prevalence of comorbidities such as hypertension and cardiovascular disease.

Introduction

  • Diabetes mellitus (DM), particularly type 2 diabetes mellitus (T2DM), is a chronic metabolic disorder characterized by hyperglycemia.
  • Dyslipidemia (abnormalities in blood lipid levels) is a common comorbidity in T2DM and is associated with increased risk of cardiovascular complications.
  • Platelets play a crucial role in hemostasis and thrombosis, and their function is altered in various pathological conditions, including diabetes.

Aims and Objectives

  • To check platelet indices (MPV, P-LCR) in patients with type 2 diabetes mellitus and dyslipidemia.
  • To correlate platelet indices (MPV, P-LCR) level in patients with type 2 diabetes mellitus and dyslipidemia.

Review of Literature

  • Provides information about type 2 diabetes, its signs and symptoms, diagnosis, management and complications like cardiovascular disease.
  • Discusses the pathophysiology of diabetes, including insulin resistance and the role of genetic factors.
  • Examines the links between diabetic dyslipidemia, platelet indices, and various other clinical and laboratory parameters in the context of type 2 diabetes.
  • Provides information (symptoms, causes, treatments, and risks) on other relevant conditions associated with the main subject.

Materials and Methods

  • Describes the study design, including the cross-sectional nature of the study, recruitment criteria, and the duration of the study. (August 2022 to January 2024)
  • Details the clinical and laboratory parameters and methods of evaluation. This will include, but isn't limited to, Blood tests, urine tests, physical examination, etc.
  • Explains the ethical considerations for the study

Results

  • The results were presented numerically in tables and graphs, using various parameters to show the differences and relationships between the experimental group (with dyslipidemia) and the control group (without dyslipidemia).
  • The section included demographics (age, gender, duration of diabetes), glycemic control (fasting plasma glucose, HbA1c), lipid profile (total cholesterol, LDL, HDL, triglycerides, VLDL), platelet indices (MPV, P-LCR), renal function, liver function, thyroid function, and comorbidities as well as medication usage.

Discussion

  • Discusses the findings, their significance, and the limitations of the study, including potential mechanisms, and comparison with previous studies.

Conclusion

  • Summarizes the key findings and implications of the study: Participants with dyslipidemia had significantly worse glycemic control, lipid profiles, and higher prevalence of comorbidities. Also, suggests areas for future research on potential mechanisms between factors including platelet function, renal function and dyslipidemia.

Summary

  • Offers a concise overview of the study's methodologies and findings, with emphasis on the statistical significance of correlations and connections between variables.

Bibliography

  • Lists all cited sources and references.

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Description

This quiz explores the acknowledgments section typically found in medical research dissertations. Questions cover the individuals and groups who provided guidance, support, and cooperation during the study. Test your understanding of the importance of these contributions in the research process.

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