Podcast
Questions and Answers
Which individual is acknowledged for their guidance and encouragement?
Which individual is acknowledged for their guidance and encouragement?
- Dr. Karthik Sasalu
- Dr. Rakesh SP
- Dr. Malthesha M.K. (correct)
- Dr. Sanjay Kumar
What role did the Superintendent of Chigateri General Hospital play in the study?
What role did the Superintendent of Chigateri General Hospital play in the study?
- Reviewed the dissertation
- Conducted the study
- Provided necessary information (correct)
- Assisted in patient care
Which group of individuals received a heartful thanks for their cooperation in the study?
Which group of individuals received a heartful thanks for their cooperation in the study?
- Post-graduate colleagues
- Family members
- Senior doctors
- Patients (correct)
Which individual is listed first among the author’s family members for support?
Which individual is listed first among the author’s family members for support?
Who assisted in the computerized layout of the dissertation?
Who assisted in the computerized layout of the dissertation?
What is the full form of the abbreviation 'HbA1c'?
What is the full form of the abbreviation 'HbA1c'?
Which term refers to the study known as the United Kingdom Prospective Diabetes Study?
Which term refers to the study known as the United Kingdom Prospective Diabetes Study?
What does the abbreviation 'T2DM' stand for?
What does the abbreviation 'T2DM' stand for?
Which abbreviation represents 'Low-density lipoprotein'?
Which abbreviation represents 'Low-density lipoprotein'?
What does 'SMBG' stand for in diabetes management?
What does 'SMBG' stand for in diabetes management?
Which of the following abbreviations refers to 'Diabetes Control and Complications Trial'?
Which of the following abbreviations refers to 'Diabetes Control and Complications Trial'?
The abbreviation 'PAI-1' refers to what?
The abbreviation 'PAI-1' refers to what?
What does the abbreviation 'ACE2' represent?
What does the abbreviation 'ACE2' represent?
What section of the document would you refer to for the methodology used in the study?
What section of the document would you refer to for the methodology used in the study?
In which section would you find the demographic and basic clinical characteristics of participants?
In which section would you find the demographic and basic clinical characteristics of participants?
Which annexure would provide insight into the patient consent process?
Which annexure would provide insight into the patient consent process?
Where would you find the results of lipid profiles in the study?
Where would you find the results of lipid profiles in the study?
Which section concludes the document by summarizing findings?
Which section concludes the document by summarizing findings?
What would you expect to find in Annexure III?
What would you expect to find in Annexure III?
Which element is NOT listed as a table in the document?
Which element is NOT listed as a table in the document?
What is the purpose of Section 8 in the document?
What is the purpose of Section 8 in the document?
What was the primary objective of the study?
What was the primary objective of the study?
How many participants in the study had dyslipidemia?
How many participants in the study had dyslipidemia?
What statistical parameter was used to compare the two groups in the study?
What statistical parameter was used to compare the two groups in the study?
Which clinical parameter was notably higher in participants with dyslipidemia?
Which clinical parameter was notably higher in participants with dyslipidemia?
What condition is closely associated with dyslipidemia as noted in the study?
What condition is closely associated with dyslipidemia as noted in the study?
Which of the following is NOT mentioned as a parameter evaluated in relation to dyslipidemia?
Which of the following is NOT mentioned as a parameter evaluated in relation to dyslipidemia?
What was the sample size of the study participants?
What was the sample size of the study participants?
What type of study design was used for this research?
What type of study design was used for this research?
Who is the lead author of the dissertation?
Who is the lead author of the dissertation?
What is the focus of the study in the dissertation?
What is the focus of the study in the dissertation?
In which year was the dissertation submitted?
In which year was the dissertation submitted?
Who guided the author of the dissertation?
Who guided the author of the dissertation?
What position does Dr.HARISHA E.J. hold?
What position does Dr.HARISHA E.J. hold?
Which college is associated with the dissertation?
Which college is associated with the dissertation?
What degree is the dissertation submitted for?
What degree is the dissertation submitted for?
Which of the following individuals is NOT mentioned in the acknowledgement section?
Which of the following individuals is NOT mentioned in the acknowledgement section?
Flashcards
What is the main research objective of the study?
What is the main research objective of the study?
The study aims to explore the connection between dyslipidemia (abnormal levels of fats and cholesterol) and specific platelet indices (MPV and P-LCR) in patients with type 2 diabetes.
What does MPV stand for?
What does MPV stand for?
Mean Platelet Volume (MPV) is a measurement indicating the average size of platelets, which are involved in blood clotting.
What does P-LCR stand for?
What does P-LCR stand for?
Platelet-Large Cell Ratio (P-LCR) is a measurement reflecting the proportion of large-sized platelets in the blood.
What is type 2 diabetes?
What is type 2 diabetes?
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What is dyslipidemia?
What is dyslipidemia?
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What are platelets?
What are platelets?
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Where is this research taking place?
Where is this research taking place?
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Who is the author of this dissertation?
Who is the author of this dissertation?
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Cardiologist
Cardiologist
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Endocrinologist
Endocrinologist
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Nephrologist
Nephrologist
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Physician (M.D.)
Physician (M.D.)
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Specialist
Specialist
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What is CHD?
What is CHD?
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What is HbA1c?
What is HbA1c?
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What is LDL?
What is LDL?
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What is HDL?
What is HDL?
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What is Type 2 Diabetes (T2DM)?
What is Type 2 Diabetes (T2DM)?
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What is IGT?
What is IGT?
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What is BMI?
What is BMI?
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What is the ADVANCE study?
What is the ADVANCE study?
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What is MPV?
What is MPV?
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What is P-LCR?
What is P-LCR?
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What is methodology?
What is methodology?
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What is discussion?
What is discussion?
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What is conclusion?
What is conclusion?
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What is a cross-sectional study?
What is a cross-sectional study?
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What is mean platelet volume (MPV)?
What is mean platelet volume (MPV)?
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What is platelet-large cell ratio (P-LCR)?
What is platelet-large cell ratio (P-LCR)?
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What is the main study objective?
What is the main study objective?
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What does the 'lipid profile' section of the study involve?
What does the 'lipid profile' section of the study involve?
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Why are participants categorized into groups based on dyslipidemia?
Why are participants categorized into groups based on dyslipidemia?
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Study Notes
Dissertation Title and Details
- Title: "A STUDY OF CORRELATION BETWEEN TYPE 2 DIABETIC DYSLIPIDEMIA WITH PLATELET INDICES-MPV, P-LCR”
- Candidate: Dr. HARSHITH M.
- Submitted to: Rajiv Gandhi University of Health Sciences, Karnataka, Bangalore
- Under the guidance of: Dr. U.R. RAAJU. M.D. (Associate Professor)
- Department: Department of General Medicine
- College: J.J.M Medical College
- Location: Davangere - 577 004
- Year: 2024
Declaration by the Candidate
- The candidate declares the dissertation is original research work
Certificate by the Guide
- The guide confirms the dissertation is original research work by the candidate
Endorsement by the HOD, Principal/Head of the Institution
- The HOD and Principal endorse the dissertation is original research work and complies with all requirements
Copyright
- The candidate agrees to the rights of Rajiv Gandhi University of Health Sciences, Karnataka to preserve, use, and disseminate the dissertation in print or electronic format for academic or research purpose
Acknowledgement
- Expresses gratitude to all those who helped during the research
- Specifically thanks their guide, Dr. U.R. RAAJU
- Acknowledges the support of other professors, and the college/hospital staff
- Thanks their parents and family members
List of Abbreviations
- This section includes a list of abbreviations used in the dissertation with their full forms.
Table of Contents
- Provides a detailed overview of the content of the dissertation with page numbers.
List of Tables
- This section lists the tables with relevant page numbers
List of Figures
- This section lists the figures with relevant page numbers
Graphs
- This section lists the graphs with relevant page numbers
Abstract
- The study investigated the association between platelet indices (MPV and P-LCR) and diabetic dyslipidemia in patients with type 2 diabetes.
- Participants with dyslipidemia had significantly higher levels of MPV and P-LCR compared to those without dyslipidemia.
- They also had poorer glycemic control (higher HbA1c levels), worse lipid profiles (higher total cholesterol, LDL cholesterol; lower HDL cholesterol) and higher prevalence of comorbidities such as hypertension and cardiovascular disease.
Introduction
- Diabetes mellitus (DM), particularly type 2 diabetes mellitus (T2DM), is a chronic metabolic disorder characterized by hyperglycemia.
- Dyslipidemia (abnormalities in blood lipid levels) is a common comorbidity in T2DM and is associated with increased risk of cardiovascular complications.
- Platelets play a crucial role in hemostasis and thrombosis, and their function is altered in various pathological conditions, including diabetes.
Aims and Objectives
- To check platelet indices (MPV, P-LCR) in patients with type 2 diabetes mellitus and dyslipidemia.
- To correlate platelet indices (MPV, P-LCR) level in patients with type 2 diabetes mellitus and dyslipidemia.
Review of Literature
- Provides information about type 2 diabetes, its signs and symptoms, diagnosis, management and complications like cardiovascular disease.
- Discusses the pathophysiology of diabetes, including insulin resistance and the role of genetic factors.
- Examines the links between diabetic dyslipidemia, platelet indices, and various other clinical and laboratory parameters in the context of type 2 diabetes.
- Provides information (symptoms, causes, treatments, and risks) on other relevant conditions associated with the main subject.
Materials and Methods
- Describes the study design, including the cross-sectional nature of the study, recruitment criteria, and the duration of the study. (August 2022 to January 2024)
- Details the clinical and laboratory parameters and methods of evaluation. This will include, but isn't limited to, Blood tests, urine tests, physical examination, etc.
- Explains the ethical considerations for the study
Results
- The results were presented numerically in tables and graphs, using various parameters to show the differences and relationships between the experimental group (with dyslipidemia) and the control group (without dyslipidemia).
- The section included demographics (age, gender, duration of diabetes), glycemic control (fasting plasma glucose, HbA1c), lipid profile (total cholesterol, LDL, HDL, triglycerides, VLDL), platelet indices (MPV, P-LCR), renal function, liver function, thyroid function, and comorbidities as well as medication usage.
Discussion
- Discusses the findings, their significance, and the limitations of the study, including potential mechanisms, and comparison with previous studies.
Conclusion
- Summarizes the key findings and implications of the study: Participants with dyslipidemia had significantly worse glycemic control, lipid profiles, and higher prevalence of comorbidities. Also, suggests areas for future research on potential mechanisms between factors including platelet function, renal function and dyslipidemia.
Summary
- Offers a concise overview of the study's methodologies and findings, with emphasis on the statistical significance of correlations and connections between variables.
Bibliography
- Lists all cited sources and references.
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Description
This quiz explores the acknowledgments section typically found in medical research dissertations. Questions cover the individuals and groups who provided guidance, support, and cooperation during the study. Test your understanding of the importance of these contributions in the research process.