Acinobacter Infections
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Questions and Answers

how does acinobacter enter the body and what diseases can it cause

infects the skin and mucous membrane especially after burns. if untreated it can cause bloodstream infections, pneumonia and UTIs

how does acinobacter cause infection?

secretion systems: export surface adhesins and inject effectors into competing strains and transport BAP. biofilm formation resistance to disinfection

why is acinobacter so resistant to disinfection

can pump out disinfectants through the acinobacter efflux protien

what are the mechanisms of resistance?

<p>beta-lactam hydrolysis: beta-lactamases degrade beta-lactam antibiotics like penicillin. modification of aminoglycoside antibodies to make them inactive. eflux pumps which pump out antibiotics and changing the outer membrane</p> Signup and view all the answers

treatment stratergies for acinobacter infection

<p>b-lactamase inhibitors, polymyxins and combination therapy</p> Signup and view all the answers

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