5 Questions
how does acinobacter enter the body and what diseases can it cause
infects the skin and mucous membrane especially after burns. if untreated it can cause bloodstream infections, pneumonia and UTIs
how does acinobacter cause infection?
secretion systems: export surface adhesins and inject effectors into competing strains and transport BAP. biofilm formation resistance to disinfection
why is acinobacter so resistant to disinfection
can pump out disinfectants through the acinobacter efflux protien
what are the mechanisms of resistance?
beta-lactam hydrolysis: beta-lactamases degrade beta-lactam antibiotics like penicillin. modification of aminoglycoside antibodies to make them inactive. eflux pumps which pump out antibiotics and changing the outer membrane
treatment stratergies for acinobacter infection
b-lactamase inhibitors, polymyxins and combination therapy
Learn how Acinobacter enters the body and the various diseases it can cause. Test your knowledge on the pathogenesis and clinical manifestations of Acinobacter infections.
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