Acid-Base Imbalances: Metabolic & Respiratory Acidosis
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Questions and Answers

What is a primary cause of metabolic acidosis?

  • Hyperventilation leading to decreased CO2
  • Increased Na+ reabsorption from diuretics
  • Increased acid loss due to vomiting
  • Defect in kidney's ability to excrete H+ (correct)

What compensatory mechanism occurs in respiratory acidosis?

  • Hyperventilation to increase oxygen levels
  • Increased HCO3+ excretion
  • Reduced H+ retention
  • Retention of bicarbonate (HCO3+) (correct)

Which treatment is commonly used for metabolic acidosis?

  • Mechanical ventilation
  • Infusion of isotonic saline
  • Intravenous bicarbonate solutions (correct)
  • Oral ammonium chloride

What is a potential cause of metabolic alkalosis?

<p>Loss of HCl due to vomiting (C)</p> Signup and view all the answers

During which condition would you expect to see bradypnea as a compensatory response?

<p>Alkalosis metabolic (A)</p> Signup and view all the answers

Which of the following symptoms is associated with respiratory alkalosis?

<p>Increased lactic acid production (B)</p> Signup and view all the answers

What is the treatment for alkalosis respiratory?

<p>Use of a plastic bag to breathe CO2 enriched air (D)</p> Signup and view all the answers

Which condition represents a respiratory problem leading to acidosis?

<p>Pulmonary edema (B)</p> Signup and view all the answers

What common response is seen in the kidney as compensation for metabolic acidosis?

<p>Increased H+ excretion and bicarbonate retention (C)</p> Signup and view all the answers

Which of the following activities typically leads to respiratory alkalosis?

<p>High altitude breathing (D)</p> Signup and view all the answers

Flashcards

Metabolic Acidosis Cause

Kidney issues (renal insufficiency), loss of bicarbonate, increased acid intake (like diabetes or drug ingestion), or low aldosterone.

Metabolic Acidosis Compensation

Faster breathing (hyperpnea) to get rid of excess CO2, kidneys working to retain bicarbonate.

Respiratory Acidosis Cause

Lung problems (pneumonia, emphysema), drug use depressing the breathing center, or high CO2 levels.

Respiratory Acidosis Treatment

Improve breathing, possibly with mechanical ventilation, to get CO2 levels under control.

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Metabolic Alkalosis Cause

Excessive acid loss (vomiting), diuretics, or taking alkaline substances.

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Metabolic Alkalosis Compensation

Slower breathing (bradypnea), and the kidneys adjust by getting rid of bicarbonate or holding onto acid.

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Respiratory Alkalosis Cause

Hyperventilation (like anxiety), low oxygen levels, or other high stimulation of breathing.

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Respiratory Alkalosis Treatment

Reduce fast breathing to normalize CO2 levels.

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Metabolic Acidosis Treatment

Administering bicarbonate or using slightly alkaline solutions.

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Metabolic Alkalosis Treatment

Using substances like ammonium chloride or other corrective solutions.

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Study Notes

Acid-Base Imbalances: Metabolic Acidosis

  • Causes:

    • Renal dysfunction impairing H+ excretion and HCO3- reabsorption
    • Loss of bicarbonate (e.g., diarrhea, fistula)
    • Increased acid production (e.g., diabetes, starvation, certain drugs)
    • Toxic ingestion (e.g., methanol, salicylates)
  • Compensation:

    • Increased breathing rate and depth (hyperventilation)
    • Kidneys attempt to increase bicarbonate reabsorption and decrease H+ excretion
  • Treatment:

    • Administering sodium bicarbonate
    • Correcting the underlying cause
    • Providing isotonic electrolyte solutions

Acid-Base Imbalances: Respiratory Acidosis

  • Causes:

    • Reduced lung function (e.g., pneumonia, pulmonary edema, asthma)
    • Drug overdose suppressing respiratory center
    • Conditions leading to increased CO2 in exhaled air
  • Compensation:

    • Kidneys attempt to retain bicarbonate and excrete H+
  • Treatment:

    • Improving lung function (e.g., ventilatory support)
    • Correcting associated issues

Acid-Base Imbalances: Metabolic Alkalosis

  • Causes:

    • Loss of stomach acid (e.g., vomiting)
    • Diuretic use increasing sodium reabsorption and hydrogen excretion
    • Excessive use of bicarbonate or alkaline drugs
    • Aldosteronism imbalance
  • Compensation:

    • Reduced breathing rate and depth (hypoventilation)
    • Kidneys attempt to reduce bicarbonate reabsorption and increase excretion of H+
  • Treatment:

    • Giving chloride to replace lost ions
    • Correcting underlying conditions

Acid-Base Imbalances: Respiratory Alkalosis

  • Causes:

    • Hyperventilation (e.g., anxiety, panic attacks)
    • High altitude
    • Some drug overdose
  • Compensation:

    • Kidneys attempt to excrete bicarbonate
  • Treatment:

    • Addressing the cause of hyperventilation
    • In some cases, breathing retraining

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Description

Test your knowledge on acid-base imbalances, focusing on metabolic and respiratory acidosis. This quiz covers causes, compensation mechanisms, and treatment options for these conditions. Perfect for students in medical or health-related fields.

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