Acid-Base Balance in Physiology
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Questions and Answers

What is the pH range for normal blood acidity?

  • 7.0 to 6.9
  • 6.8 to 7.2
  • 7.35 to 7.45 (correct)
  • 7.0 to 7.8

Which condition is indicated by a blood pH lower than 7.35?

  • Alkalosis
  • Neutralization
  • Buffering
  • Acidosis (correct)

What does a neutral solution have on the pH scale?

  • pH of 5
  • pH of 8
  • pH of 7 (correct)
  • pH of 6

What happens if the blood pH exceeds 7.6?

<p>It leads to alkalosis. (C)</p> Signup and view all the answers

How does an increase in hydrogen ions affect pH?

<p>Decreases pH and makes the solution acidic. (B)</p> Signup and view all the answers

What distinguishes volatile acids from nonvolatile acids in the body?

<p>Volatile acids are in equilibrium with carbon dioxide. (B)</p> Signup and view all the answers

Which of the following is an example of a nonvolatile acid?

<p>Sulfuric acid (B), Hydrochloric acid (D)</p> Signup and view all the answers

How are nonvolatile acids primarily eliminated from the body?

<p>Buffered by body proteins and eliminated by the kidneys. (C)</p> Signup and view all the answers

What is the main reason the lungs do not eliminate nonvolatile acids?

<p>The lungs only exhale volatile compounds. (B)</p> Signup and view all the answers

What characteristic do most acids and bases in the body share?

<p>They are primarily weak acids and bases. (A)</p> Signup and view all the answers

What is the primary function of buffers in the body?

<p>To neutralize strong acids and bases (A)</p> Signup and view all the answers

Which of the following describes the major buffer system in the body?

<p>Carbonic acid–bicarbonate buffer system (C)</p> Signup and view all the answers

What is the normal bicarbonate level in the body?

<p>22 to 26 mEq/L (A)</p> Signup and view all the answers

What happens to the pH of the body when the bicarbonate to carbonic acid ratio deviates from 20:1?

<p>The pH may become too acidic or too alkaline (C)</p> Signup and view all the answers

Which body process is responsible for excreting carbonic acid?

<p>The lungs through respiration (D)</p> Signup and view all the answers

What is the primary role of the respiratory center in the brain?

<p>Controlling the rate of elimination of carbon dioxide (A)</p> Signup and view all the answers

What occurs when the respiratory center detects excessive hydrogen ions?

<p>Increased rate and depth of breathing (D)</p> Signup and view all the answers

How does chronic obstructive pulmonary disease (COPD) affect the body's compensatory ability?

<p>It impairs compensatory ability due to decreased respiratory function (A)</p> Signup and view all the answers

What happens to respiration when low levels of hydrogen ions are detected?

<p>Respirations are decreased and carbon dioxide is retained (A)</p> Signup and view all the answers

What is the time frame for compensation to occur in response to increased hydrogen ion concentration?

<p>Minutes (B)</p> Signup and view all the answers

Which factor do the kidneys regulate to compensate for acid-base disturbances?

<p>Hydrogen ions (A)</p> Signup and view all the answers

What is the primary outcome when the kidneys excrete more hydrogen ions?

<p>Increased pH in the blood (C)</p> Signup and view all the answers

How does aging affect the kidneys' ability to compensate for acid-base imbalances?

<p>It reduces their compensatory effectiveness (C)</p> Signup and view all the answers

In cases of high pH, what adjustment do the kidneys make?

<p>Reabsorb more hydrogen ions (A)</p> Signup and view all the answers

What dual role do the kidneys and lungs play in maintaining acid-base balance?

<p>They regulate both acid and base levels (A)</p> Signup and view all the answers

What pH level indicates metabolic acidosis?

<p>Below 7.35 (A)</p> Signup and view all the answers

Which condition is characterized by a bicarbonate concentration greater than 26 mEq/L?

<p>Metabolic alkalosis (A)</p> Signup and view all the answers

What can lead to an acid-base imbalance due to inadequate compensation?

<p>Compensatory mechanisms failing (B)</p> Signup and view all the answers

Which of the following best describes metabolic acidosis?

<p>Increase in carbonic acid and decrease in bicarbonate (B)</p> Signup and view all the answers

What is the primary acid-base imbalance observed in patients with chronic obstructive pulmonary disease (COPD)?

<p>Respiratory acidosis due to CO2 retention (A)</p> Signup and view all the answers

What is one potential cause of metabolic acidosis related to uncontrolled diabetes?

<p>Metabolizing fats leads to acidic ketone bodies (A)</p> Signup and view all the answers

Which condition contributes to metabolic acidosis due to dietary restrictions?

<p>Eating disorders or acute alcoholism (A)</p> Signup and view all the answers

What role do the kidneys play in metabolic acidosis when chronic renal failure occurs?

<p>Inability to excrete hydrogen ions (A)</p> Signup and view all the answers

Which of the following best describes a consequence of an increase in hydrogen ions in the context of metabolic acidosis?

<p>Lower pH levels in the blood (A)</p> Signup and view all the answers

What is a common by-product produced during lipid metabolism in the development of metabolic acidosis?

<p>Ketone bodies (B)</p> Signup and view all the answers

Which of the following can lead to systemic lactic acidosis?

<p>Cardiac arrest (D)</p> Signup and view all the answers

How does excessive exercise contribute to metabolic acidosis?

<p>Encourages anaerobic energy production (D)</p> Signup and view all the answers

What is a consequence of salicylate toxicity in relation to metabolic acidosis?

<p>Direct acid production in the bloodstream (D)</p> Signup and view all the answers

Which drug class is associated with lactic acidosis due to mitochondrial damage?

<p>Nucleoside reverse transcriptase inhibitors (B)</p> Signup and view all the answers

What effect does spironolactone have that can lead to metabolic acidosis?

<p>Conserves hydrogen ions in the blood (A)</p> Signup and view all the answers

Which of the following conditions can lead to decreased bicarbonate levels in the body?

<p>Severe diarrhea (A)</p> Signup and view all the answers

What is a potential consequence of excessive use of laxatives in relation to bicarbonate levels?

<p>Decreased bicarbonate levels (C)</p> Signup and view all the answers

Which category of drugs can contribute to the loss of bicarbonate from the kidneys?

<p>Carbonic anhydrase inhibitors (D)</p> Signup and view all the answers

What is a possible effect of chemotherapy drugs on bicarbonate levels?

<p>Inhibition of bicarbonate reabsorption (B)</p> Signup and view all the answers

What metabolic condition can result from the excessive loss of bicarbonate?

<p>Metabolic acidosis (B)</p> Signup and view all the answers

What is a direct effect of bile acid sequestrant drugs on chloride ion levels?

<p>They trigger the release of negatively charged chloride ions. (D)</p> Signup and view all the answers

How does excessive administration of sodium chloride intravenous fluids affect chloride levels?

<p>It leads to an increase in negatively charged chloride ions. (C)</p> Signup and view all the answers

What is one of the outcomes of increased chloride ions in the blood?

<p>Metabolic acidosis. (A)</p> Signup and view all the answers

What mechanism leads to metabolic acidosis following the use of bile acid sequestrant drugs?

<p>Absorption of excess negatively charged chloride ions. (B)</p> Signup and view all the answers

Which scenario is most likely to cause an increase in metabolic acidosis due to chloride ions?

<p>Rapid infusion of sodium chloride intravenous fluids. (B)</p> Signup and view all the answers

What causes metabolic alkalosis in patients who vomit excessively?

<p>Decreased hydrogen ions in the blood (D)</p> Signup and view all the answers

Which medication is commonly associated with the development of metabolic alkalosis due to chloride loss?

<p>Furosemide (A)</p> Signup and view all the answers

How does excessive use of sodium bicarbonate affect the body's acid-base balance?

<p>Increases bicarbonate levels in the blood (D)</p> Signup and view all the answers

Which of these can lead to metabolic alkalosis by reducing chloride ions?

<p>Overuse of loop diuretics (A)</p> Signup and view all the answers

Which scenario is NOT a typical cause of metabolic alkalosis?

<p>Chronic kidney failure (D)</p> Signup and view all the answers

What is a primary cause of respiratory acidosis?

<p>Narcotic overdose leading to decreased respiratory rate (B)</p> Signup and view all the answers

Which of the following conditions is NOT a cause of respiratory acidosis?

<p>Frequent high-intensity exercise (C)</p> Signup and view all the answers

How does airway blockage contribute to respiratory acidosis?

<p>By preventing carbon dioxide exhalation, leading to its accumulation (C)</p> Signup and view all the answers

Which lung disease is associated with respiratory acidosis?

<p>Asthma (A)</p> Signup and view all the answers

What physiological change occurs due to respiratory acidosis?

<p>Accumulation of carbon dioxide in the blood (A)</p> Signup and view all the answers

What primarily causes respiratory alkalosis in the body?

<p>Sustained hyperventilation (C)</p> Signup and view all the answers

Which of the following conditions can lead to hyperventilation?

<p>Severe anxiety (B)</p> Signup and view all the answers

Which hormonal change is likely to contribute to respiratory alkalosis?

<p>Elevated thyroid hormone levels (D)</p> Signup and view all the answers

How does salicylate overdose affect respiration?

<p>Stimulates the respiratory center in the brain (C)</p> Signup and view all the answers

Which physiological response is NOT associated with respiratory alkalosis?

<p>Inhibition of thyroid hormone production (B)</p> Signup and view all the answers

Which condition is most likely to result in increased acid production leading to metabolic acidosis?

<p>Diabetic ketoacidosis (B)</p> Signup and view all the answers

What is a potential consequence of excessive use of laxative drugs?

<p>Decreased bicarbonate levels (D)</p> Signup and view all the answers

What can result from excessive chloride intake via intravenous solutions?

<p>Metabolic acidosis (C)</p> Signup and view all the answers

Which of the following conditions is associated with decreased acid excretion leading to metabolic acidosis?

<p>Renal failure (C)</p> Signup and view all the answers

Which condition could lead to bicarbonate loss, potentially causing metabolic acidosis?

<p>Intestinal fistula (B)</p> Signup and view all the answers

What condition is characterized by increased bicarbonate levels in the blood?

<p>Metabolic alkalosis (C)</p> Signup and view all the answers

What is a common cause of acid loss leading to metabolic alkalosis?

<p>Vomiting (C)</p> Signup and view all the answers

Which of the following best describes a potential consequence of hypokalemia in the context of metabolic alkalosis?

<p>Increased bicarbonate retention (D)</p> Signup and view all the answers

Excessive intake of which substance can directly contribute to metabolic alkalosis?

<p>Sodium bicarbonate (A)</p> Signup and view all the answers

What might excessive bicarbonate administration lead to?

<p>Metabolic alkalosis (D)</p> Signup and view all the answers

Which of the following conditions is most likely associated with acute respiratory acidosis?

<p>Pulmonary edema (C)</p> Signup and view all the answers

What is a potential cause of chronic respiratory acidosis?

<p>Stroke (B)</p> Signup and view all the answers

Which of these scenarios would NOT be classified as a cause of acute respiratory acidosis?

<p>Chronic obstructive pulmonary disease (D)</p> Signup and view all the answers

Which respiratory condition is most often linked to chronic respiratory acidosis?

<p>Cystic fibrosis (A)</p> Signup and view all the answers

Which of the following can lead to acute respiratory acidosis due to respiratory failure?

<p>Opiate overdose (A)</p> Signup and view all the answers

Which condition is NOT typically associated with respiratory alkalosis?

<p>Hypoventilation (B)</p> Signup and view all the answers

What is a common cause of hyperventilation that can lead to respiratory alkalosis?

<p>Anxiety-induced hyperventilation (C)</p> Signup and view all the answers

Which scenario can potentially trigger respiratory alkalosis?

<p>High altitude exposure (B)</p> Signup and view all the answers

Early salicylate intoxication may result in respiratory alkalosis due to which mechanism?

<p>Direct stimulation of the respiratory center (D)</p> Signup and view all the answers

Which statement about mechanical ventilation and respiratory alkalosis is true?

<p>It can induce respiratory alkalosis if the settings are too high. (D)</p> Signup and view all the answers

What is the primary compensation mechanism of the lungs in response to metabolic acidosis?

<p>Increasing the rate and depth of respirations (C)</p> Signup and view all the answers

Which of the following describes a method by which the kidneys compensate for respiratory acidosis?

<p>Conserving bicarbonate (C)</p> Signup and view all the answers

What change occurs in arterial blood gases during metabolic alkalosis?

<p>Increased pH and increased HCO3 (C)</p> Signup and view all the answers

What compensatory action do the kidneys take in cases of respiratory alkalosis?

<p>Excreting bicarbonate and conserving hydrogen ions (C)</p> Signup and view all the answers

What is the expected change in the bicarbonate to carbonic acid ratio during metabolic acidosis?

<p>Decrease below 20:1 (B)</p> Signup and view all the answers

What changes do the lungs make to compensate for metabolic acidosis?

<p>Increase the rate and depth of respiration (C)</p> Signup and view all the answers

Which adaptation do the kidneys make in response to respiratory alkalosis?

<p>Excrete bicarbonate and conserve hydrogen ions (C)</p> Signup and view all the answers

What is the effect on arterial blood gases during metabolic alkalosis?

<p>Increased pH and increased bicarbonate (D)</p> Signup and view all the answers

What compensatory mechanism is utilized by the kidneys during respiratory acidosis?

<p>Conservation of bicarbonate (C)</p> Signup and view all the answers

In the event of metabolic acidosis, which of the following occurs in arterial blood gas analysis?

<p>Decreased pH and decreased HCO3 (D)</p> Signup and view all the answers

What occurs in respiratory acidosis concerning hydrogen ions and bicarbonate?

<p>Excess hydrogen is excreted in urine and bicarbonate is retained. (B)</p> Signup and view all the answers

In the case of metabolic alkalosis, how does the respiratory system respond?

<p>By decreasing ventilation to retain carbon dioxide. (D)</p> Signup and view all the answers

What is the classification of compensation when the pH partially returns to normal?

<p>Partially compensated (D)</p> Signup and view all the answers

Which factor primarily influences acid-base imbalances in critically ill patients?

<p>Underlying causes and treatments. (A)</p> Signup and view all the answers

How does renal function adjust in metabolic acidosis if compensation is occurring?

<p>By increasing hydrogen ion excretion and retaining bicarbonate. (C)</p> Signup and view all the answers

What is a potential consequence of respiratory acidosis in patients?

<p>Altered mental status (D)</p> Signup and view all the answers

What should be monitored closely in patients experiencing changes in acid-base balance?

<p>Level of consciousness (C)</p> Signup and view all the answers

What is a potential risk associated with rapid administration of sodium bicarbonate?

<p>Metabolic alkalosis (A)</p> Signup and view all the answers

In metabolic acidosis, particularly in cases of DKA, what is an important treatment approach?

<p>Administer insulin and IV fluids (A)</p> Signup and view all the answers

Which of the following strategies can help alleviate anxiety related breathing difficulties?

<p>Teach guided imagery (B)</p> Signup and view all the answers

What effect does hypoventilation have on blood gas levels?

<p>Increased carbon dioxide levels (C)</p> Signup and view all the answers

What is an important consideration when managing a patient with acute respiratory distress?

<p>Perform frequent respiratory assessments (D)</p> Signup and view all the answers

What can result from untreated tissue perfusion issues due to acid-base imbalance?

<p>Cardiac arrest (A)</p> Signup and view all the answers

What chronic condition might lead to fluid imbalances and subsequent acid-base disturbances?

<p>Diabetes (B)</p> Signup and view all the answers

Which medication-related factor is most likely to influence sodium and potassium levels in the body?

<p>Antihypertensives (B)</p> Signup and view all the answers

What main focus should nurses emphasize in patient education regarding chronic illness management?

<p>Adhere to medication and nutrition plans (C)</p> Signup and view all the answers

Which of the following conditions is NOT typically associated with fluid balance disturbances?

<p>Gout (B)</p> Signup and view all the answers

Which of the following can result from both overhydration and dehydration in relation to fluid balance?

<p>Acid-base imbalances (D)</p> Signup and view all the answers

Which factor is NOT essential to assess when identifying patients at risk for acid–base disturbances?

<p>Patient's dietary preferences (B)</p> Signup and view all the answers

What might indicate an underlying respiratory or metabolic problem in a patient?

<p>Decreased level of consciousness (B)</p> Signup and view all the answers

Which of the following is least likely to correlate with a patient's diagnosis regarding acid–base imbalances?

<p>Measuring blood hemoglobin levels (D)</p> Signup and view all the answers

How should a nurse assess ventilatory abnormalities during a focused assessment?

<p>By counting the patient's respirations for a full minute (B)</p> Signup and view all the answers

Which patient condition is most likely to lead to significant acid–base disturbances?

<p>Severe electrolyte imbalances (D)</p> Signup and view all the answers

What is essential to determine the underlying cause of acid-base imbalance in a patient?

<p>A complete health history including medication usage (C)</p> Signup and view all the answers

Which symptom may indicate a change in acid-base balance during a physical examination?

<p>Changes in skin color and temperature (C)</p> Signup and view all the answers

Why should fall precautions be implemented for patients with decreased level of consciousness (LOC)?

<p>Decreased LOC can lead to disorientation and instability. (A)</p> Signup and view all the answers

Which of the following vital signs is NOT specifically listed as a measure during the assessment of acid-base balance?

<p>Blood pressure (D)</p> Signup and view all the answers

What role do complementary health approaches play in assessing acid-base balance?

<p>They can affect physiological components and impact health status. (B)</p> Signup and view all the answers

What is the primary reason arterial blood gases (ABGs) are preferred over venous or capillary blood for assessing acid-base balance?

<p>Arterial blood reflects acid-base balance better than venous blood. (B)</p> Signup and view all the answers

In what scenario would venous blood gases be ordered instead of arterial blood gases?

<p>When frequent ABGs have damaged arterial sampling sites. (C)</p> Signup and view all the answers

What specific test must be performed before drawing arterial blood gases to ensure safety?

<p>Modified Allen test for ulnar patency. (B)</p> Signup and view all the answers

What important information about lung function can arterial blood provide?

<p>It indicates the effectiveness of gas exchange in external respiration. (B)</p> Signup and view all the answers

What type of blood sample serves as an indicator of chronic serum retention, particularly when lung disease is chronic?

<p>Serum metabolic panel. (B)</p> Signup and view all the answers

What is the primary reason for applying pressure at the puncture site after drawing ABGs?

<p>To reduce the risk of bleeding or bruising (C)</p> Signup and view all the answers

Which guideline is suggested for routine surveillance of patients instead of using ABGs?

<p>Pulse oximetry (B)</p> Signup and view all the answers

Who is authorized to draw blood gases according to the guidelines?

<p>Respiratory therapists and specially trained HCPs (C)</p> Signup and view all the answers

What is the first step in analyzing ABG results systematically?

<p>Analyze each individual measurement (D)</p> Signup and view all the answers

What is one consequence of overusing ABGs in clinical practice?

<p>Increased healthcare costs and patient discomfort (D)</p> Signup and view all the answers

What does pulse oximetry primarily measure in the body?

<p>Peripheral arterial oxygen saturation (C)</p> Signup and view all the answers

Which condition is NOT likely to cause false readings in pulse oximetry?

<p>Dehydration (D)</p> Signup and view all the answers

Why is it especially important to obtain accurate readings from pulse oximetry in clinical settings today?

<p>Fewer arterial blood gases (ABGs) are conducted (D)</p> Signup and view all the answers

What should a clinician do if pulse oximetry readings appear inaccurate?

<p>Consider an arterial blood gas analysis (C)</p> Signup and view all the answers

Which of the following best describes the key limitation of pulse oximetry?

<p>It can produce false readings under certain clinical conditions. (B)</p> Signup and view all the answers

What is the primary function of pulse oximetry?

<p>To assess peripheral arterial oxygen saturation (C)</p> Signup and view all the answers

In which situation is pulse oximetry particularly indicated?

<p>In cases of potential hypoxemia (D)</p> Signup and view all the answers

Which factor could lead to a false reading in a pulse oximetry test?

<p>Carbon monoxide poisoning (D)</p> Signup and view all the answers

What should a clinician do if they suspect inaccurate pulse oximetry readings?

<p>Obtain arterial blood for analysis (A)</p> Signup and view all the answers

Which statement accurately describes the relationship between pulse oximetry and arterial blood gas (ABG) results?

<p>ABGs provide a detailed analysis that can confirm pulse oximetry results (A)</p> Signup and view all the answers

What condition is indicated by a partial pressure of carbon dioxide greater than 45 mmHg?

<p>Hypoventilation (B)</p> Signup and view all the answers

What is the normal range for the partial pressure of oxygen in the blood?

<p>80 to 100 mmHg (A)</p> Signup and view all the answers

Which measure indicates the amount of oxygen carried by hemoglobin in red blood cells?

<p>Oxygen saturation (A)</p> Signup and view all the answers

What does a decreased level of oxygen saturation below 95% indicate?

<p>Hypoxemia (C)</p> Signup and view all the answers

What is the main use of measuring oxygen saturation in patients?

<p>To gauge oxygenation status (B)</p> Signup and view all the answers

What is the role of bicarbonate in blood pH regulation?

<p>It serves as a chemical buffer to maintain pH balance. (D)</p> Signup and view all the answers

Which range is considered a normal anion gap?

<p>8 to 16 mEq/L (C)</p> Signup and view all the answers

What does a base excess (BE) value indicate in arterial blood?

<p>The overall level of bases in the blood. (D)</p> Signup and view all the answers

How is the anion gap calculated?

<p>Sodium - Chloride - Bicarbonate (A)</p> Signup and view all the answers

What indicates metabolic alkalosis in terms of bicarbonate levels?

<p>Bicarbonate level greater than 26 mEq/L (B)</p> Signup and view all the answers

What is an independent intervention that a nurse should perform for acid-base management?

<p>Monitor intake and output (C)</p> Signup and view all the answers

Which vital assessment should be included when evaluating a patient's condition related to acid-base imbalances?

<p>Assessing respiratory and renal function (A)</p> Signup and view all the answers

Which of the following factors should the nurse consider when taking a patient's health history for acid-base assessment?

<p>Current medications (C)</p> Signup and view all the answers

What type of information may need to be gathered from family or friends during the nurse's assessment in cases of severe distress?

<p>Recent dietary preferences and exercise habits (D)</p> Signup and view all the answers

What is one key reason for monitoring the oxygen saturation of a patient with suspected acid-base imbalances?

<p>To determine respiratory function (D)</p> Signup and view all the answers

What is the primary method for administering insulin during collaborative management?

<p>Continuous IV infusion (A)</p> Signup and view all the answers

Why is potassium monitoring crucial during treatment?

<p>To ensure electrolyte balance during hyperkalemia correction. (B)</p> Signup and view all the answers

What are common over-the-counter antacid drugs used to correct hyperacidity?

<p>Sodium bicarbonate, aluminum hydroxide, and magnesium hydroxide (A)</p> Signup and view all the answers

What serious condition can result from severe untreated metabolic acidosis?

<p>Myocardial depression (A)</p> Signup and view all the answers

How do antacid drugs primarily function in treating hyperacidity?

<p>By neutralizing gastric acid locally in the stomach. (B)</p> Signup and view all the answers

Which class of medication inhibits gastric acid production and can be used to treat hyperacidity?

<p>Proton pump inhibitors (B)</p> Signup and view all the answers

What is the benefit of bicarbonate as a treatment for hyperacidity?

<p>It neutralizes excessive gastric acid. (C)</p> Signup and view all the answers

What can excessive amounts of gastric acid lead to if not properly managed?

<p>Heartburn and gastric ulcers. (B)</p> Signup and view all the answers

What is the primary method used to manage insulin levels in a patient undergoing collaborative management?

<p>Continuous IV infusion adjusted by glucose levels (B)</p> Signup and view all the answers

Which electrolyte requires careful monitoring when correcting hyperkalemia in a patient?

<p>Potassium (C)</p> Signup and view all the answers

What is the primary action of proton pump inhibitors in managing gastric acid imbalance?

<p>Inhibiting the proton pump to decrease acid production (B)</p> Signup and view all the answers

In cases of systemic acid-base imbalance, what type of treatment is required?

<p>Systemic medications (B)</p> Signup and view all the answers

What serious condition can occur if severe metabolic acidosis remains untreated?

<p>Multiorgan failure (B)</p> Signup and view all the answers

What is the function of antacid drugs in relation to gastric acid?

<p>Neutralize excessive gastric acid (D)</p> Signup and view all the answers

What is a notable risk associated with the correction of hyperkalemia?

<p>Hypokalemia (A)</p> Signup and view all the answers

Which of the following is a common side effect or condition linked to hyperacidity in the stomach?

<p>Heartburn (D)</p> Signup and view all the answers

Under what condition is intubation generally indicated for a patient experiencing respiratory distress?

<p>pH less than 7.20 (A), PaO2 less than 60 mmHg (B)</p> Signup and view all the answers

What is a potential complication when correcting chronic hypercapnia too quickly?

<p>Metabolic alkalosis (C)</p> Signup and view all the answers

Which condition can be treated with BiPAP therapy without the need for immediate intubation?

<p>Severe respiratory distress with acute respiratory acidosis (B)</p> Signup and view all the answers

Why is it important to monitor patients receiving BiPAP therapy?

<p>To prevent pneumothorax and hypotension (D)</p> Signup and view all the answers

What treatment is indicated for patients with hypoxemia to improve outcomes?

<p>Supplemental oxygen (D)</p> Signup and view all the answers

Flashcards

Acidic Solution pH

A solution with a pH lower than 7.

Alkaline/Basic Solution pH

A solution with a pH higher than 7.

Blood pH

7.4 (normal range 7.35 to 7.45).

Acidosis

Blood pH lower than 7.35.

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Alkalosis

Blood pH greater than 7.45.

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Volatile Acid

An acid like carbonic acid that is in equilibrium with a volatile gas (CO2) that can be exhaled by the lungs.

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Nonvolatile Acid

An acid that is not in equilibrium with a volatile gas and cannot be excreted by the lungs. They are eliminated by the kidneys.

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How are Volatile Acids Excreted?

Volatile acids are excreted by the lungs through exhalation of carbon dioxide (CO2).

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How are Nonvolatile Acids Excreted?

Nonvolatile acids are buffered by body proteins or bicarbonate and then eliminated by the kidneys.

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Weak Acids and Bases

Most acids and bases in the body are weak, meaning they do not significantly release or accept hydrogen ions.

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Buffer System Role

Buffers are essential in maintaining the proper pH balance in body fluids by either releasing hydrogen ions when the solution is too alkaline or absorbing them when it's too acidic.

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Carbonic Acid-Bicarbonate Buffer

The major buffer system in the body, it neutralizes strong acids by forming bicarbonate ions, thus preventing drastic changes in pH.

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What happens to Carbonic Acid?

Carbonic acid breaks down into carbon dioxide (CO2) and water (H2O). CO2 is then exhaled by the lungs, helping to regulate the pH balance within the body.

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Normal Bicarbonate Level

In the blood, the typical bicarbonate level is 24 mEq/L, ranging from 22 to 26 mEq/L.

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pH Balance and the 20:1 Ratio

The body maintains a 20:1 ratio of bicarbonate to carbonic acid in extracellular fluids, which helps keep the blood pH within the normal range of 7.35-7.45.

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Respiratory Center's Role

The respiratory center in the brain controls breathing rate to maintain proper blood pH. It increases breathing when there's too much acid (hydrogen ions) and decreases breathing when there's too little acid.

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Hyperventilation: Why?

Hyperventilation occurs when the respiratory center is stimulated by high levels of acid (hydrogen ions) in the blood. This increased breathing rate and depth expels more carbon dioxide, reducing acidity.

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Hypoventilation: Why?

Hypoventilation occurs when the respiratory center senses low acid (hydrogen ions) levels. Breathing slows down, retaining carbon dioxide and increasing blood acidity.

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COPD and Compensation

People with COPD have impaired respiratory function, making it harder for them to compensate for changes in blood acidity. Their bodies are less able to adjust breathing rate effectively.

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Fast vs. Slow Compensation

Compensation for increased acidity occurs within minutes, but it becomes less effective over time, especially for people with COPD.

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Kidney Compensation

The process by which the kidneys regulate the pH of blood by adjusting the excretion of hydrogen ions and bicarbonate.

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Acid-Base Disturbances

Conditions where the pH of the blood is too low (acidosis) or too high (alkalosis).

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How do kidneys compensate for acidosis?

The kidneys excrete more hydrogen ions (acid) and reabsorb more bicarbonate (base) to raise the pH.

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How do kidneys compensate for alkalosis?

The kidneys reabsorb more hydrogen ions (acid) and excrete more bicarbonate (base) to lower the pH.

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Kidney Compensation in Elderly

Older adults have a reduced ability to compensate for acid-base imbalances due to age-related decline in kidney function.

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What is an acid-base imbalance?

A change in the ratio of 20:1 between the acid and base content in the body. This can happen due to disease or inadequate compensation for changes in acid or base levels.

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What are the two main types of acid-base imbalances?

Acidosis: Blood pH is too low (below 7.35). Alkalosis: Blood pH is too high (above 7.45).

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What are metabolic acid-base imbalances?

These imbalances occur due to problems with the body's ability to produce or eliminate acids and bases. This affects the bicarbonate levels in the blood.

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What are respiratory acid-base imbalances?

These imbalances occur due to problems with the lungs' ability to remove carbon dioxide, which affects the carbonic acid levels in the blood.

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How are metabolic acidosis and alkalosis defined?

Metabolic Acidosis: Increased carbonic acid or decreased bicarbonate. pH falls below 7.35, bicarbonate less than 22 mEq/L. Metabolic Alkalosis: Decreased carbonic acid or increased bicarbonate. pH rises above 7.45, bicarbonate greater than 26 mEq/L.

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Metabolic Acidosis

A condition where the blood becomes too acidic due to an increase in hydrogen ions, a decrease in bicarbonate, or an increase in chloride ions.

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Causes of Increased Hydrogen Ions

Uncontrolled diabetes, starvation, or chronic kidney failure can all lead to an increase in hydrogen ions in the blood.

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Diabetic Ketoacidosis

When the body can't use glucose for energy due to lack of insulin, it breaks down fat, producing acidic ketone bodies, leading to metabolic acidosis.

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Starvation and Acidosis

Restricting calories to a point of starvation depletes glucose stores and forces the body to metabolize fat, producing ketones, causing metabolic acidosis.

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Role of Kidneys in Acidosis

In chronic renal failure, kidneys are unable to properly eliminate hydrogen ions, leading to their build-up in the blood and metabolic acidosis.

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Causes of Metabolic Acidosis

Metabolic acidosis can be caused by various factors, including diabetes, shock, heart failure, sepsis, or even excessive exercise.

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Lactic Acidosis

A type of metabolic acidosis caused by a build-up of lactic acid in the body, often due to lack of oxygen during exercise or conditions like heart failure.

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Salicylate Toxicity

Overdose of aspirin (acetylsalicylic acid) can cause metabolic acidosis.

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Antidiabetic Drugs and Acidosis

Certain diabetes medications (like metformin) can cause lactic acidosis, especially in people with kidney problems.

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What causes metabolic acidosis due to bicarbonate loss?

Severe diarrhea, intestinal fistula, or excessive laxative use depletes bicarbonate from the intestine, leading to metabolic acidosis.

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How do kidney problems cause metabolic acidosis?

Damaged kidneys cannot reabsorb bicarbonate, causing excessive loss in urine, resulting in metabolic acidosis.

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Bicarbonate Loss from Kidney Drugs

Drugs like acetazolamide (Diamox Sequels) and certain chemotherapy drugs can block bicarbonate reabsorption or damage the kidneys, leading to metabolic acidosis.

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Metabolic Acidosis and Bicarbonate

Metabolic acidosis is often characterized by a decrease in bicarbonate levels in the blood.

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How do drugs contribute to metabolic acidosis?

Drugs like carbonic anhydrase inhibitors, acetazolamide, and chemotherapy drugs can disrupt bicarbonate balance, leading to metabolic acidosis.

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Chloride Ions & Acidosis

High levels of chloride ions in the blood can cause metabolic acidosis. This usually happens when the body absorbs too many chloride ions, as seen with certain medications or excessive intravenous fluids.

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Bile Acid Sequestrants and Chloride

Bile acid sequestrant drugs, like cholestyramine, bind to bile in the gut, releasing chloride ions. These ions are then absorbed into the blood, potentially leading to metabolic acidosis.

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Intravenous Fluids and Chloride

Overuse of sodium chloride intravenous fluids directly raises chloride levels in the blood, causing metabolic acidosis.

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What causes metabolic acidosis?

Metabolic acidosis is an acid-base imbalance where the blood becomes too acidic (low pH) due to an increase in hydrogen ions, a decrease in bicarbonate, or an increase in chloride ions.

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Metabolic Acidosis: Causes

Metabolic acidosis can be caused by various factors including diabetes, starvation, chronic kidney failure, excessive exercise, certain medications like metformin or aspirin, severe diarrhea, or excessive laxative use.

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Metabolic Alkalosis

A condition where the blood becomes too alkaline (high pH) due to a decrease in hydrogen ions, a decrease in chloride ions, or an increase in bicarbonate.

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Causes of Metabolic Alkalosis

Metabolic alkalosis can be caused by excessive vomiting, excessive use of loop diuretic drugs like furosemide, or excessive use of sodium bicarbonate.

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Excessive Vomiting & Metabolic Alkalosis

Excessive vomiting, often caused by infections or eating disorders, reduces hydrochloric acid in the stomach and hydrogen ions in the blood, leading to metabolic alkalosis.

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Loop Diuretics & Metabolic Alkalosis

Loop diuretics, such as furosemide, cause the loss of chloride ions in the urine, leading to metabolic alkalosis.

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Sodium Bicarbonate & Metabolic Alkalosis

Excessive use of sodium bicarbonate (baking soda) directly increases bicarbonate levels in the blood, causing metabolic alkalosis.

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Respiratory Acidosis

A condition where the blood becomes too acidic due to a buildup of carbon dioxide.

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Causes of Respiratory Acidosis

Respiratory acidosis can be caused by decreased breathing rate, decreased air volume inhaled/exhaled, or blocked airways.

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Narcotics and Respiratory Acidosis

Opioids (narcotics) can cause respiratory acidosis by slowing down breathing, leading to CO2 retention.

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Lung Diseases and Respiratory Acidosis

Conditions like asthma, COPD, or pneumonia make it harder to breathe, resulting in CO2 buildup and acidosis.

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Airway Blockage and Respiratory Acidosis

A blocked airway, like from a foreign object, prevents breathing and causes CO2 accumulation, leading to acidosis.

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Respiratory Alkalosis

A condition where the blood becomes too alkaline due to excessive removal of carbon dioxide from the lungs, usually caused by hyperventilation.

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Hyperventilation Causes

Hyperventilation can be triggered by anxiety, pain, stress, excess thyroid hormone, high altitudes, or certain drugs like aspirin. Each of these situations cause an increase in breathing rate.

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How does hyperventilation cause alkalosis?

Hyperventilation leads to the removal of excess CO2 from the lungs, which lowers the carbonic acid level in the blood, resulting in a higher pH (alkalosis).

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Respiratory Alkalosis Symptoms

Respiratory alkalosis can cause symptoms like dizziness, lightheadedness, tingling sensations, and muscle cramps.

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Respiratory Alkalosis Treatment

Treatment for respiratory alkalosis usually involves slowing down breathing rate and, in some cases, correcting the underlying cause of hyperventilation.

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Hyperventilation & Respiratory Alkalosis

Hyperventilation leads to the removal of excess CO2 from the lungs, which lowers the carbonic acid level in the blood, resulting in a higher pH (alkalosis).

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What is metabolic alkalosis?

Metabolic alkalosis is a condition where the blood becomes too alkaline (high pH) due to a decrease in hydrogen ions, a decrease in chloride ions, or an increase in bicarbonate.

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What are some causes of metabolic alkalosis?

Excessive vomiting, excessive use of loop diuretic drugs like furosemide, or excessive use of sodium bicarbonate can all lead to metabolic alkalosis.

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How does excessive vomiting lead to metabolic alkalosis?

Excessive vomiting, often caused by infections or eating disorders, reduces hydrochloric acid in the stomach and hydrogen ions in the blood, leading to metabolic alkalosis.

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How do loop diuretics cause metabolic alkalosis?

Loop diuretics, such as furosemide, cause the loss of chloride ions in the urine, leading to metabolic alkalosis.

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Why does excessive use of sodium bicarbonate lead to metabolic alkalosis?

Excessive use of sodium bicarbonate (baking soda) directly increases bicarbonate levels in the blood, causing metabolic alkalosis.

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Acute Respiratory Acidosis

A sudden onset of respiratory acidosis, often caused by acute respiratory conditions like pneumonia, pulmonary edema, or foreign body aspiration.

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Chronic Respiratory Acidosis

A long-term, persistent case of respiratory acidosis, often due to chronic respiratory conditions like COPD or cystic fibrosis.

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Respiratory Acidosis Treatment

Treatment for respiratory acidosis focuses on addressing the underlying cause, such as improving breathing mechanics, removing airway obstructions, or providing oxygen therapy.

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Anxiety-Induced Hyperventilation

A common cause of respiratory alkalosis where anxiety triggers rapid and deep breathing, leading to excessive CO2 loss and increased blood pH.

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Early Salicylate Intoxication

Overdose of aspirin (acetylsalicylic acid) can cause respiratory alkalosis in the early stages, due to its stimulant effect on the respiratory center.

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Hyperventilation with Mechanical Ventilator

A potential complication of mechanical ventilation where the machine sets the breathing rate too high, leading to excessive CO2 loss and respiratory alkalosis.

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Fever & Respiratory Alkalosis

Elevated body temperature (fever) can trigger a rapid breathing rate, leading to excess CO2 expulsion and respiratory alkalosis.

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What is compensation in acid-base balance?

When one system (lungs or kidneys) tries to balance out the pH changes caused by the other system.

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How do lungs compensate for metabolic acidosis?

The lungs increase breathing rate and depth to eliminate more carbon dioxide, which reduces acidity.

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How do kidneys compensate for respiratory alkalosis?

The kidneys conserve hydrogen ions and excrete bicarbonate to restore the normal ratio of bicarbonate to carbonic acid.

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How do kidneys compensate for respiratory acidosis?

The kidneys conserve bicarbonate and excrete hydrogen ions to restore the normal ratio of bicarbonate to carbonic acid.

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How do lungs compensate for metabolic alkalosis?

The lungs decrease breathing rate and depth to retain carbon dioxide, which increases acidity.

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Respiratory Acidosis Compensation

The kidneys compensate by conserving bicarbonate (base) and excreting hydrogen ions (acid) to restore the normal ratio of bicarbonate to carbonic acid.

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Metabolic Acidosis Compensation

The lungs compensate by increasing ventilation to eliminate more carbon dioxide, reducing the acidity of the blood.

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Respiratory Alkalosis Compensation

The kidneys compensate by conserving hydrogen ions (acid) and excreting bicarbonate (base) to restore the normal ratio of bicarbonate to carbonic acid.

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Metabolic Alkalosis Compensation

The lungs compensate by decreasing ventilation to retain more carbon dioxide, increasing the acidity of the blood.

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Fully Compensated

When a body successfully restores its pH back to normal range after an acid-base imbalance.

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Acid-Base Imbalance

A disruption in the balance of acids and bases in the body, leading to changes in blood pH.

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Compensation (Acid-Base)

The process where one body system (lungs or kidneys) tries to balance pH changes caused by the other system.

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Fluid Imbalance & Acid-Base

Changes in fluid balance, like overhydration or dehydration, can disrupt the body's acid-base balance, leading to imbalances like acidosis or alkalosis.

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Chronic Conditions & Acid-Base

Chronic conditions like diabetes, kidney disease, and lung disease can easily disrupt fluid balance, causing acid-base imbalances.

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Electrolyte Imbalances

Changes in electrolytes, especially sodium and potassium, due to medications, supplements, or diets, can contribute to acid-base imbalances.

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Nursing Focus on Acid-Base

Nurses educate patients on proper nutrition, taking medications as prescribed, and managing chronic conditions to prevent acid-base imbalances.

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Acid-Base Imbalance and Medications

Certain medications, supplements, or changes in diet can lead to electrolyte imbalances, affecting acid-base balance.

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What are the key factors to consider when assessing acid-base imbalances?

A focused assessment includes identifying patients at risk, like those with electrolyte imbalances, net acid/base gains/losses, ventilation problems, kidney issues, and metabolic problems. Also, evaluate vital signs, respiratory rate and depth, consciousness, fluid balance, and kidney function.

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What is the significance of decreased LOC in a patient?

A decreased level of consciousness (LOC) could indicate an acid-base disturbance. The body's pH can impact brain function.

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Why is it important to correlate findings with the patient's diagnosis?

Understanding the patient's existing medical conditions is crucial because certain diagnoses can predispose them to specific acid-base imbalances.

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What is the role of vital sign assessment in acid-base imbalance?

Vital sign assessment helps identify clues to potential imbalances. For example, a rapid, deep breathing pattern may indicate respiratory compensations for acidosis.

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How do fluid balance and kidney function relate to acid-base imbalance?

Fluid balance and kidney function are crucial because the kidneys play a major role in regulating pH. Abnormal kidney function can lead to difficulties in eliminating acids or bases.

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Assessing for Acid-Base Imbalances

A focused assessment includes identifying patients at risk, like those with electrolyte imbalances, net acid/base gains/losses, ventilation problems, kidney issues, and metabolic problems. Also, evaluate vital signs, respiratory rate and depth, consciousness, fluid balance, and kidney function.

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Why Arterial Blood Gases?

Arterial blood gases (ABGs) are used to assess acid-base balance in the body because arterial blood reflects the overall body's acid-base balance more accurately than venous or capillary blood.

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Modified Allen Test

A modified Allen test is performed before drawing ABGs to ensure the ulnar artery is patent, which is crucial for blood flow to the hand after the radial artery is punctured for blood sampling.

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Chronic Lung Disease and ABGs

In patients with chronic lung disease, it's helpful to look at serum electrolyte levels over time to assess the long-term impact of the disease on acid-base balance.

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When are Venous Blood Gases Used?

Venous blood gases are occasionally ordered when frequent ABG sampling has damaged normal arterial sites, providing information about acid-base balance.

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What do ABGs tell us?

Arterial blood gases (ABGs) provide information about the effectiveness of the lungs in oxygenating blood and the overall acid-base balance in the body.

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ABG Overuse

The overuse of arterial blood gas (ABG) tests is discouraged as it can lead to increased costs, inefficient use of healthcare staff, patient discomfort, and blood loss.

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ABG Analysis Approach

Analyzing ABG results involves a systematic approach: first, evaluate each individual measurement; then, analyze the interrelationships to determine the patient's acid-base status.

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Pulse Oximetry for Surveillance

Pulse oximetry is a preferred method for routine blood oxygen monitoring, unless there are specific clinical concerns or acute events justifying ABG testing.

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Post-ABG Pressure

After drawing blood from an artery, applying pressure to the puncture site for 10 minutes (or more if the patient is on anticoagulants) helps prevent bleeding or bruising.

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Who can draw ABGs?

Arterial blood gas (ABG) samples can be drawn by respiratory therapists, healthcare providers, or nurses with specialized training (like those in intensive care units).

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Pulse Oximetry

A non-invasive test that measures the percentage of oxygenated hemoglobin in the blood, providing an indication of tissue oxygenation.

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Pulse Oximetry: False Readings

Pulse oximetry can give inaccurate readings in conditions like anemia, carbon monoxide poisoning, hypothermia, and poor blood flow.

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Pulse Oximetry: Importance of ABG

While pulse oximetry is helpful, it's crucial to confirm its readings with an arterial blood gas (ABG) test, especially in cases of suspected oxygenation problems.

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When is Pulse Oximetry Indicated?

Pulse oximetry is recommended in any setting where low blood oxygen levels (hypoxemia) might occur.

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Pulse Oximetry: Limitations

While generally accurate, pulse oximetry has limitations and can provide false readings under certain conditions, necessitating further investigation with ABG analysis.

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Pulse Oximetry Uses

Pulse oximetry is used to monitor oxygen levels in patients with conditions like respiratory problems, heart disease, or during surgery.

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Importance of Correlation

It's essential to compare pulse oximetry readings with results from arterial blood gas (ABG) tests, especially when readings are abnormal.

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False Readings

False readings from pulse oximetry can occur due to factors like anemia, carbon monoxide poisoning, or poor blood flow.

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Partial Pressure of Carbon Dioxide (PCO2)

The pressure of carbon dioxide dissolved in the blood, reflecting how well CO2 is removed from the body. It's a key indicator of ventilation efficiency.

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Normal PCO2 Range

The typical range of PCO2 in a healthy individual is 35 to 45 mmHg.

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What does a high PCO2 indicate?

A high PCO2 (above 45 mmHg) indicates hypoventilation, meaning the lungs are not exhaling enough CO2.

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What does a low PCO2 indicate?

A low PCO2 (below 35 mmHg) indicates hyperventilation, meaning the lungs are exhaling too much CO2.

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Partial Pressure of Oxygen (PO2)

The pressure of oxygen dissolved in the blood, reflecting how well oxygen moves from the lungs into the blood.

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Bicarbonate

Bicarbonate is a chemical buffer that helps to maintain the pH of blood. Normal levels are 22 to 26 mEq/L. Low levels indicate acidosis and high levels indicate alkalosis.

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Anion Gap

The anion gap is a calculation that measures the difference between major electrolytes (sodium, potassium, chloride, and bicarbonate). It helps determine the cause of acid-base imbalances.

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Base Excess (BE)

Base excess is a calculated buffer that reflects the level of bicarbonate and other bases in the blood. It is a measure of increased or decreased bicarbonate.

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What is metabolic acidosis?

Metabolic acidosis is a condition where the blood becomes too acidic. This can be caused by an increase in hydrogen ions, a decrease in bicarbonate, or an increase in chloride ions.

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Acid-Base Imbalance Signs

Physical signs that might suggest an acid-base imbalance include changes in breathing, like rapid or shallow breaths, altered mental state, like confusion or drowsiness, and changes in heart rate.

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Factors Affecting Acid-Base

Factors like fluid imbalance, electrolyte imbalances, chronic conditions, and certain medications can influence acid-base balance in the body.

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Why Assess Kidney Function?

Assessing kidney function is critical because the kidneys play a key role in removing acids from the body and maintaining pH balance.

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Connecting Findings with Diagnosis?

It's important to connect the patient's medical history and diagnosis with their acid-base findings because some conditions make them more prone to specific imbalances.

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Vital Signs Clues

Vital signs can provide clues about acid-base imbalance. For example, a rapid, deep breathing pattern might indicate the body is trying to remove excess acid by exhaling more carbon dioxide.

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What is respiratory alkalosis?

A condition where the blood becomes too alkaline due to excessive removal of carbon dioxide from the lungs, usually caused by hyperventilation.

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Causes of Respiratory Alkalosis

Hyperventilation can be triggered by anxiety, pain, stress, excess thyroid hormone, high altitudes, or certain drugs like aspirin.

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What is the role of antacids?

Antacids are alkaline substances used to neutralize excessive gastric acid, correcting hyperacidity. They work locally within the stomach to restore acid-base balance.

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What are proton pump inhibitors (PPIs)?

PPIs are medications that inhibit the proton pump in the stomach, decreasing the production of gastric acid. They also work locally to correct acid-base imbalance.

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How does the body maintain acid-base balance systemically?

Systemic acid-base imbalances affect the entire body and require medications that act systemically to correct the imbalance. The body's balance is disrupted by many diseases, and localized treatments are insufficient.

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What is diabetic ketoacidosis?

Diabetic ketoacidosis is a serious condition where the body can't use glucose for energy due to lack of insulin. It breaks down fat, producing acidic ketone bodies, leading to metabolic acidosis.

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How do lung diseases affect acid-base balance?

Lung diseases like COPD and pneumonia can make it harder to breathe, leading to a build-up of carbon dioxide and respiratory acidosis. It's like having a clogged exhaust pipe in a car.

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Intubation Indication

Intubation is often indicated when a patient's respiratory distress is severe, as evidenced by a PaCO2 greater than 77 mmHg, a PaO2 less than 60 mmHg, and a pH less than 7.20.

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Chronic Hypercapnia and Correction

Patients with chronically high carbon dioxide levels (hypercapnia) should have their condition corrected gradually. Too rapid correction can cause metabolic alkalosis due to the body retaining too much bicarbonate.

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Supplemental Oxygen for Hypoxemia

Patients with low oxygen levels (hypoxemia) can benefit from supplemental oxygen. Studies show this improves outcomes and reduces mortality rates.

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BiPAP Therapy Criteria

Bilevel Positive Airway Pressure (BiPAP) is a potential alternative to intubation for certain patients with severe respiratory distress and acute respiratory acidosis, especially when intubation is not feasible.

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BiPAP Therapy Complications

Patients receiving BiPAP therapy should be monitored for complications such as pneumothorax (collapsed lung) and hypotension (low blood pressure) due to decreased venous return.

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Study Notes

Acid-Base Balance

  • Acid-base balance is crucial for homeostasis and cell function.
  • Acidity or alkalinity of a solution depends on hydrogen ion concentration.
  • High hydrogen ion concentration indicates acidity.
  • Low hydrogen ion concentration indicates alkalinity (or basicity).
  • pH measures hydrogen ion concentration.
  • The pH scale ranges from 0 to 14.
  • A pH of 7 is considered neutral.
  • A pH less than 7 is considered acidic.
  • A pH greater than 7 is considered alkaline or basic.
  • Normal blood pH is 7.4 (range 7.35-7.45); blood is slightly alkaline.
  • Normal pH signifies acid-base balance.
  • Acidosis occurs when blood pH is below 7.35.
  • Alkalosis occurs when blood pH is above 7.45.
  • Body's ability to tolerate alterations in acid-base levels is limited.
  • A pH below 7 or above 7.6, even briefly, can be fatal.

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Explore the essential concept of acid-base balance and its significance for homeostasis and cell function. Understand the pH scale, its implications for blood pH, and the conditions of acidosis and alkalosis. Test your knowledge on how these factors affect overall health.

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