24 Questions
What is the main function of nicotinic receptors at the neuromuscular junction?
Transmission of stimulation
Which subtype of muscarinic receptor is responsible for pupillary constriction in the eye?
M3
What is the main action of the METABOTROPIC M3 RECEPTOR?
Promotes contraction
Which neurotransmitter binds to the B1Adrenoreceptor in the heart?
Noradrenaline
What is the function of alpha2 adrenergic receptors?
Inhibition of transmitter release
What is the role of DAG (diacylglycerol) in the cell?
Facilitates the opening of calcium channels
What is the effect of inhibiting ADENYLYL CYCLASE?
Reduces cyclic AMP
What is the primary function of beta2 adrenergic receptors?
Relaxation of smooth muscle
What initiates the conformational change in the alpha q type of METABOTROPIC M3 RECEPTOR?
Binding of GTP
What is the primary effect of calcium on muscle cells?
Promotes contraction
What is the function of nicotinic receptors at the adrenal medulla?
Release of adrenaline and noradrenaline
Which enzyme does the activated alpha i subunit inhibit?
Adenylyl cyclase
Which receptor, when activated by noradrenaline, causes dilation of the eye?
Alpha 1 adrenoreceptor
What is the effect of circulating adrenaline on B2 adrenoceptors in the skeletal vasculature bed?
Vasodilation
Which receptor activation causes relaxation of the GI tract?
B2 adrenoceptor
Which drug acts as a selective beta agonist on bronchiole smooth muscle to produce bronchodilation?
Salbutamol
What is the primary use of mirabegron, which acts on beta3 adrenoceptors?
Treatment of overactive bladder syndrome
What is the primary purpose of antagonists on beta adrenoceptors?
Reduction of heart rate
Which drug acts antagonistically on alpha 1 adrenoceptors on arterioles to produce vasodilation?
Prazosin
What is the effect of agonist action on alpha 1 adrenoceptors in the smooth muscle of the prostate and bladder?
Contraction of the bladder
What are the side effects of non-selective beta blockers?
Reduced exercise tolerance
Which drugs are known as cardio-selective beta blockers?
Atenolol and metoprolol
What can result from the abrupt withdrawal of beta blockers?
Angina
What is the primary use of tamsulosin, a competitive antagonist on alpha 1 adrenoceptors?
Treatment of overactive bladder syndrome
Test your knowledge of acetylcholine receptors with this quiz. Explore the roles of nicotinic receptors in the parasympathetic and sympathetic ganglia, adrenal medulla, skeletal muscle, neuromuscular junction, and central nervous system. Dive into the actions of nicotinic receptors, including their involvement in ganglia transmission, skeletal muscle contraction, and the release of adrenaline and noradrenaline.
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