Acetylcholine

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Questions and Answers

Which of the following is true about acetylcholine?

  • It is synthesized from tyrosine
  • It is primarily recycled by the norepinephrine transporter (NET)
  • It is broken down by acetylcholinesterase to choline and acetic acid (correct)
  • It acts on adrenergic receptors

Where are muscarinic receptors found?

  • Only in the central nervous system
  • In all organs innervated by the parasympathetic and sympathetic nervous system (correct)
  • In the adrenal medulla
  • In the neuromuscular junction

What is the primary fate of released noradrenaline?

  • It is broken down by acetylcholinesterase
  • 75% is taken back up and recycled by the norepinephrine transporter (NET) (correct)
  • It is transported back into the nerve for recycling
  • It is primarily used for the synthesis of acetylcholine

What is the function of nicotinic receptors?

<p>Stimulation of ganglia, skeletal muscle, and release of adrenaline and noradrenaline from adrenal medulla (C)</p> Signup and view all the answers

What is the primary fate of released acetylcholine?

<p>Taken out as a whole molecule or broken down by acetylcholinesterase to choline and acetic acid (D)</p> Signup and view all the answers

Which enzyme is responsible for the synthesis of noradrenaline from tyrosine?

<p>Tyrosine hydroxylase (C)</p> Signup and view all the answers

Where are nicotinic receptors NOT found?

<p>Central nervous system (C)</p> Signup and view all the answers

How is the rest of the released noradrenaline, not taken back up for recycling, broken down?

<p>By monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT) (D)</p> Signup and view all the answers

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Study Notes

Acetylcholine

  • Acetylcholine is a neurotransmitter that plays a crucial role in various physiological processes.

Muscarinic Receptors

  • Muscarinic receptors are found in the parasympathetic nervous system, smooth muscle, and exocrine glands.

Noradrenaline

  • The primary fate of released noradrenaline is reuptake by the neuron, where it can be recycled or broken down.

Nicotinic Receptors

  • The primary function of nicotinic receptors is to regulate rapid synaptic transmission.

Acetylcholine Fate

  • The primary fate of released acetylcholine is breakdown by the enzyme acetylcholinesterase.

Noradrenaline Synthesis

  • The enzyme responsible for the synthesis of noradrenaline from tyrosine is dopamine β-hydroxylase.

Nicotinic Receptors Absence

  • Nicotinic receptors are not found in the parasympathetic nervous system.

Noradrenaline Breakdown

  • The rest of the released noradrenaline not taken back up for recycling is broken down by the enzyme monoamine oxidase or catechol-O-methyltransferase.

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