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Acetylcholine

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Questions and Answers

Which of the following is true about acetylcholine?

It is synthesized from tyrosine

It is primarily recycled by the norepinephrine transporter (NET)

It is broken down by acetylcholinesterase to choline and acetic acid (correct)

It acts on adrenergic receptors

Where are muscarinic receptors found?

Only in the central nervous system

In all organs innervated by the parasympathetic and sympathetic nervous system (correct)

In the adrenal medulla

In the neuromuscular junction

What is the primary fate of released noradrenaline?

It is broken down by acetylcholinesterase

75% is taken back up and recycled by the norepinephrine transporter (NET) (correct)

It is transported back into the nerve for recycling

It is primarily used for the synthesis of acetylcholine

What is the function of nicotinic receptors?

Stimulation of ganglia, skeletal muscle, and release of adrenaline and noradrenaline from adrenal medulla Signup and view all the answers

What is the primary fate of released acetylcholine?

Taken out as a whole molecule or broken down by acetylcholinesterase to choline and acetic acid Signup and view all the answers

Which enzyme is responsible for the synthesis of noradrenaline from tyrosine?

Tyrosine hydroxylase Signup and view all the answers

Where are nicotinic receptors NOT found?

Central nervous system Signup and view all the answers

How is the rest of the released noradrenaline, not taken back up for recycling, broken down?

By monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT) Signup and view all the answers

Study Notes

Acetylcholine

Acetylcholine is a neurotransmitter that plays a crucial role in various physiological processes.

Muscarinic Receptors

Muscarinic receptors are found in the parasympathetic nervous system, smooth muscle, and exocrine glands.

Noradrenaline

The primary fate of released noradrenaline is reuptake by the neuron, where it can be recycled or broken down.

Nicotinic Receptors

The primary function of nicotinic receptors is to regulate rapid synaptic transmission.

Acetylcholine Fate

The primary fate of released acetylcholine is breakdown by the enzyme acetylcholinesterase.

Noradrenaline Synthesis

The enzyme responsible for the synthesis of noradrenaline from tyrosine is dopamine β-hydroxylase.

Nicotinic Receptors Absence

Nicotinic receptors are not found in the parasympathetic nervous system.

Noradrenaline Breakdown

The rest of the released noradrenaline not taken back up for recycling is broken down by the enzyme monoamine oxidase or catechol-O-methyltransferase.

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Description

Test your knowledge of acetylcholine with this quiz! Learn about its formation, release, and breakdown, as well as its role in acting on cholinergic receptors. See how much you know about the enzymes involved and the recycling process of choline.