8 Questions
Which of the following is true about acetylcholine?
It is broken down by acetylcholinesterase to choline and acetic acid
Where are muscarinic receptors found?
In all organs innervated by the parasympathetic and sympathetic nervous system
What is the primary fate of released noradrenaline?
75% is taken back up and recycled by the norepinephrine transporter (NET)
What is the function of nicotinic receptors?
Stimulation of ganglia, skeletal muscle, and release of adrenaline and noradrenaline from adrenal medulla
What is the primary fate of released acetylcholine?
Taken out as a whole molecule or broken down by acetylcholinesterase to choline and acetic acid
Which enzyme is responsible for the synthesis of noradrenaline from tyrosine?
Tyrosine hydroxylase
Where are nicotinic receptors NOT found?
Central nervous system
How is the rest of the released noradrenaline, not taken back up for recycling, broken down?
By monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT)
Study Notes
Acetylcholine
- Acetylcholine is a neurotransmitter that plays a crucial role in various physiological processes.
Muscarinic Receptors
- Muscarinic receptors are found in the parasympathetic nervous system, smooth muscle, and exocrine glands.
Noradrenaline
- The primary fate of released noradrenaline is reuptake by the neuron, where it can be recycled or broken down.
Nicotinic Receptors
- The primary function of nicotinic receptors is to regulate rapid synaptic transmission.
Acetylcholine Fate
- The primary fate of released acetylcholine is breakdown by the enzyme acetylcholinesterase.
Noradrenaline Synthesis
- The enzyme responsible for the synthesis of noradrenaline from tyrosine is dopamine β-hydroxylase.
Nicotinic Receptors Absence
- Nicotinic receptors are not found in the parasympathetic nervous system.
Noradrenaline Breakdown
- The rest of the released noradrenaline not taken back up for recycling is broken down by the enzyme monoamine oxidase or catechol-O-methyltransferase.
Test your knowledge of acetylcholine with this quiz! Learn about its formation, release, and breakdown, as well as its role in acting on cholinergic receptors. See how much you know about the enzymes involved and the recycling process of choline.
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