Acetic Acid and Protogenic Solvents Quiz

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Questions and Answers

What does the term 'c - x' represent in the context of the equation provided?

  • The volume of the solution
  • The initial concentration of the solute (correct)
  • The concentration of the solute after dissociation
  • The amount of solute removed from the solution

How many moles of acetate ions were found in the 0.1 M solution of acetic acid?

  • 1.32 × 10−3 moles (correct)
  • 3.2 × 10−2 moles
  • 1.0 moles
  • 0.1 moles

At what temperature was the conductivity analysis conducted for the acetic acid solution?

  • 50°C
  • 100°C
  • 25°C (correct)
  • 0°C

What is the approximate error when replacing 'c - x' with 'c' in the equations described?

<p>Unnoticeable error (B)</p> Signup and view all the answers

What ions were dissociated from the acetic acid in the solution?

<p>Hydronium and acetate ions (D)</p> Signup and view all the answers

Which of the following compounds is NOT considered a protogenic solvent?

<p>Ether (D)</p> Signup and view all the answers

What is the primary characteristic of a protogenic solvent?

<p>It donates protons. (D)</p> Signup and view all the answers

Which of the following is an example of a protogenic solvent?

<p>Liquid ammonia (D)</p> Signup and view all the answers

How is liquid HF classified in the context of protogenic solvents?

<p>It is a weak acid. (D)</p> Signup and view all the answers

Which of the following substances would be classified under protogenic solvents?

<p>Sulfuric acid (A)</p> Signup and view all the answers

What is the range of pH values indicating acidity on the numeric scale?

<p>0 to 7 (B)</p> Signup and view all the answers

At what concentration does the H ion concentration in a strong acidic solution approximate 1?

<p>1 M (C)</p> Signup and view all the answers

Which statement accurately describes the Brønsted–Lowry nomenclature?

<p>It is particularly useful for describing ionic equilibria. (C)</p> Signup and view all the answers

What is the H ion concentration in a 1 M solution of a strong base?

<p>1 × 10-14 (B)</p> Signup and view all the answers

What does a pH value of 14 indicate about a solution?

<p>Highly alkaline (B)</p> Signup and view all the answers

What term is used for acids that donate a single proton?

<p>Monoprotic acids (C)</p> Signup and view all the answers

What do we call bases that accept a single proton?

<p>Monobasic bases (A)</p> Signup and view all the answers

What characterizes monoprotic electrolytes?

<p>They donate a single proton and accept a single proton. (A)</p> Signup and view all the answers

Which of the following describes a monoprotic acid?

<p>An acid that donates only one proton per molecule. (C)</p> Signup and view all the answers

Which of these is an example of a monoprotic electrolyte?

<p>Hydrochloric acid (HCl) (A)</p> Signup and view all the answers

What does the acidity constant Ka represent?

<p>The dissociation of a weak acid (D)</p> Signup and view all the answers

What is the relationship between the dissociation constants of a weak acid and its conjugate base?

<p>Ka is related to Kb through the amphiprotic nature of the solvent (C)</p> Signup and view all the answers

Which statement about acetic acid and its dissociation is true?

<p>Acetic acid has a measurable Ka value due to partial dissociation (D)</p> Signup and view all the answers

What factor does not affect the value of the acidity constant Ka?

<p>Concentration of the acid (D)</p> Signup and view all the answers

Under which condition would we compare Ka and Kb for an acid-base pair?

<p>When the solvent is amphiprotic (C)</p> Signup and view all the answers

What is typically assumed about the concentrations of the weak acids in a system containing two weak acids?

<p>They are much greater than K1 and K2. (B)</p> Signup and view all the answers

What ions are produced when a salt of a weak acid and a weak base, such as ammonium acetate, dissociates in aqueous solution?

<p>NH4+ and Ac− (C)</p> Signup and view all the answers

In the context of ionic equilibria, what is the primary effect of having the salts of weak acids and weak bases in solution?

<p>They lead to weak acid-base interactions in solution. (C)</p> Signup and view all the answers

Which of the following statements is true regarding the salt dissociation in weak acid and weak base systems?

<p>The salt dissociates almost completely. (D)</p> Signup and view all the answers

When considering two weak acids, which variables are assumed to be effectively zero in these systems?

<p>Ca2 and Cb2 (A)</p> Signup and view all the answers

Flashcards

Protophilic solvent

A substance capable of accepting a proton (H+ ion). Examples include acetone, ether, and liquid ammonia.

Protogenic solvent

A substance capable of donating a proton (H+ ion). Examples include formic acid, acetic acid, sulfuric acid, liquid HCl, and liquid HF.

Proton acceptor

A substance which accepts a proton (H+ ion) to form a new species.

Proton donor

A substance which donates a proton (H+ ion) to form a new species.

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Proton transfer

The ability to donate or accept a proton (H+ ion).

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Sörensen's pH

A scale used to measure the acidity or alkalinity of a solution, with values ranging from 0 to 14.

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Acidity

A solution with a pH value between 0 and 7 is considered acidic.

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Alkalinity

A solution with a pH value between 7 and 14 is considered alkaline or basic.

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pH Scale

The pH of a solution can be considered in terms of a numeric scale having values from 0 to 14, which expresses in a quantitative way the degree of acidity (7 to 0) and alkalinity (7-14).

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H+ Concentration

The H ion concentration of a solution varies from approximately 1 in a 1 M solution of a strong acid to about 1 × 10-14 in a 1 M solution of a strong base.

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What is the acidity constant (Ka)?

The equilibrium constant for the dissociation of a weak acid in water. It represents the ratio of the product of the concentrations of the dissociated ions (H+ and conjugate base) to the concentration of the undissociated acid.

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What is a proton acceptor?

A substance capable of accepting a proton (H+ ion) from another molecule. This leads to the formation of a new species.

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What is a proton donor?

A substance capable of donating a proton (H+ ion) to another molecule. This leads to the formation of a new species.

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What is proton transfer?

The process of transferring a proton (H+ ion) from one molecule to another. This process is key in acid-base reactions.

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What is an amphiprotic solvent?

A solvent that can both donate and accept protons (H+ ions). Examples include water and alcohols.

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Monoprotic electrolytes

Acids and bases that donate or accept only one proton (H+) in a reaction.

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What does a monoprotic acid donate?

One proton (H+) is released during the reaction.

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What does a monoprotic base accept?

One proton (H+) is accepted during the reaction.

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What happens to monoprotic acids and bases after proton transfer?

They form a new species after donating or accepting a proton.

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What happens during a reaction between a monoprotic acid and base?

A single proton (H+) is transferred between them.

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Neglecting 'x' in equilibrium constant expression (Kc)

In an equilibrium reaction, if the value of 'x' in the equilibrium constant expression (Kc) is significantly smaller than the initial concentration of reactants (c), then 'x' can be disregarded in the calculation. This simplified approach is valid when the change in concentration due to the reaction is negligible compared to the original concentration. By assuming that the change in concentration is negligible, we can simplify the calculation and obtain an approximation.

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Equilibrium constant (Kc)

The equilibrium constant (Kc) is a numerical value that describes the relative amounts of reactants and products at equilibrium in a reversible reaction. It is a measure of the extent to which a reaction proceeds to completion. Kc is calculated by dividing the product of the concentrations of products raised to their stoichiometric coefficients by the product of the concentrations of reactants raised to their stoichiometric coefficients.

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Molarity (M)

A solution's molarity is a measure of its concentration, defined as the number of moles of solute present in one liter of solution. A 0.1 M solution contains 0.1 moles of solute in one liter of solution.

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Ionization constant (Ka)

The degree to which a weak acid dissociates in solution is represented by its ionization constant (Ka). It reflects the equilibrium constant for the acid's dissociation reaction.

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Acetate ions and hydronium ions

Acetate ions (CH3COO-) and hydronium ions (H3O+) are formed when acetic acid (CH3COOH) dissolves in water. Acetic acid is a weak acid that only partially ionizes in solution.

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Simplifying pH Calculation in Systems with Two Weak Acids

In solutions containing two weak acids, the concentrations of the conjugate bases (Cb1 and Cb2) are assumed to be zero. Additionally, the concentrations of the acids (Ca1 and Ca2) are significantly greater than their respective dissociation constants (K1 and K2). This simplifies the calculation of pH and allows for the direct use of the simplified equation.

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Salt of a Weak Acid and Weak Base Dissociation

Solutions containing a salt of a weak acid and a weak base, like ammonium acetate, dissociate almost completely in water. The cation (e.g., NH4+) acts as an acid (HB1), and the anion (e.g., Ac-) acts as a base (B2-) in the equilibrium.

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pH Determination in Salt of Weak Acid and Base Solutions

The pH of a solution containing a salt of a weak acid and a weak base is determined by the relative strengths of the acid and base components of the salt.

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Hydrolysis Equilibrium Constant

The equilibrium constant for the hydrolysis of a salt of a weak acid and a weak base is given by the product of the acid dissociation constant (Ka) and the base dissociation constant (Kb).

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pH Calculation for Salt of Weak Acid and Base

The pH of a solution containing a salt of a weak acid and a weak base can be calculated using the Henderson-Hasselbalch equation, which relates the pH to the pKa of the acid component and the ratio of the concentrations of the conjugate acid and base.

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Study Notes

Physical Pharmacy I - 2nd Stage

  • Topic: Ionic Equilibria (2024-2025)

Objectives

  • Define acids and bases
  • Understand Sörensen's pH scale
  • Understand terminology like Ampholytes, Aprotic, etc.
  • Explain ionization of Polyprotic electrolytes
  • Calculate pKa and pH of aqueous solutions with different compositions

Theories

  • Arrhenius Theory:

    • Acid: A substance releasing hydrogen ions.
    • Base: A substance releasing hydroxide ions upon dissociation in aqueous media.
  • Brønsted-Lowry Theory:

    • Acid: A substance donating a proton.
    • Base: A substance accepting a proton.
    • Conjugate acid-base pairs explained.

Solvent Classification

  • Protophilic/Basic: Accepts protons from the solute.
  • Protogenic: Donates protons to the solute.
  • Amphiprotic: Can both accept and donate protons, e.g., water.
  • Aprotic: Neither accept nor donate protons, e.g., hydrocarbons.

Proteolytic Reactions (Protolysis)

  • Acid-base reactions involving proton transfer.
  • Also known as protonation-deprotonation reactions.

Sörensen's pH

  • pH scale quantifies acidity and alkalinity (0-14).
  • pH 7 is neutral, equal hydrogen and hydroxyl ion concentrations.
  • pH values at different temperatures are stated.

Ionic Equilibria

  • Equilibrium: A balance between opposing forces/reactions.
  • Dynamic equality between opposing reaction velocities.
  • Equilibrium condition where standard free energy difference is zero.
  • Explanation of the equilibrium constants involved in the process

Lewis Electronic Theory

  • Acid: Accepts an electron pair.
  • Base: Donates an electron pair.

Ionization of Polyprotic Electrolytes

  • Acids/bases donating/accepting multiple protons.
  • Diprotic (e.g., carbonic acid) and triprotic (e.g., phosphoric acid) acids ionizing in multiple stages.

Ampholytes

  • Species acting as both acid and base.
  • Amino acids and proteins are amphoteric/ampholytes.
  • Explanation of zwitterions.

Isoelectric Point (IEP)

  • pH where zwitterion concentration is maximum for protein and amino acids
  • Represents the point at which the molecule has no net charge.
  • Solubility and other properties depend on the IEP.
  • pH of milk and casein has been stated.

Solutions Containing Strong Acids

  • H+ ion concentration fully ionizes.
  • H+ concentration is equal to the concentration of the strong acid.

Solutions Containing Weak Acids

  • Incomplete ionization
  • Calculate the pH using equilibrium expressions: [H₃O+] = √(KₐCₐ)

Solutions Containing a Single Conjugate Acid-Base Pair

  • Calculate pH for solutions with both a weak acid and its salt (conjugate base) or vice versa.
  • Using the respective acid dissociation constant (Kₐ) or conjugate base dissociation constants (Kᵦ), or K₁ and K₂ constants involved in this type of equilibria equations

Solutions Containing Two Weak Acids

  • The dominant equilibrium occurs via the equation [H₃O+] = √(K₁C₁ + K₂C₂) .
  • Examples of calculating pH have been given when considering the concentration of two weak acids by using their K₁ and K₂ constants

Solutions Containing a Salt of a Weak Acid and a Weak Base

  • The overall ionization process involves the ionization of the weak base and/or weak acid.
  • The overall ionization process is often complicated due to the presence of multiple species.
  • In most instances, [H₃O+] = √K₁K₂

Solutions Containing a Weak Acid and A Weak Base

  • Calculation of pH using the equilibrium expression with K₁ and K₂
  • Examples have been given for both weak acid and weak base types of solutions

Ionic Strength

  • A measure of the total ion concentration in a solution.
  • The calculation of ionic strength has been mentioned for various types of electrolytes

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