ACE Inhibitors Mechanism of Action
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Questions and Answers

What is the primary mechanism by which ACE inhibitors decrease blood pressure?

  • Vasodilation leading to decreased total peripheral resistance (correct)
  • Decreased release of aldosterone leading to promote renal excretion of sodium and water
  • Inhibition of angiotensin II’s action on vascular growth
  • Inhibition of renin release

    • Which of the following is NOT a mechanism of action of ACE inhibitors?

  • Inhibition of angiotensin II’s action on vascular growth
  • Inhibition of bradykinin metabolism
  • Decreased release of aldosterone leading to promote renal excretion of sodium and water
  • Stimulation of the sympathetic nervous system (correct)

    • What is the most likely cause of dry cough in patients taking ACE inhibitors?

  • Inhibition of angiotensin II’s action on vascular growth
  • Decreased aldosterone release
  • Increased bradykinin (correct)
  • Inhibition of bradykinin metabolism

    • Which of the following is a potential adverse effect of ACE inhibitors?

    <p>Hyperkalemia</p> Signup and view all the answers

    What is the mechanism by which ACE inhibitors promote renal excretion of sodium and water?

    <p>Decreased release of aldosterone</p> Signup and view all the answers

    Why may ACE inhibitors need to be changed to ARBs in some patients?

    <p>Due to dry cough</p> Signup and view all the answers

    What is the mechanism of action of Angiotensin II Receptor Blockers (ARBs) in reducing blood pressure?

    <p>Blockage of AT1 receptors</p> Signup and view all the answers

    Which of the following diuretics is a competitive antagonist of aldosterone receptors at distal tubule and collecting ducts?

    <p>Spironolactone</p> Signup and view all the answers

    What is the mechanism of action of Sacubitril + Valsartan in reducing blood pressure?

    <p>Inhibition of neprilysin enzyme</p> Signup and view all the answers

    What is the common side effect of beta-adrenoreceptor blockers that is not seen with ACE inhibitors?

    <p>Fatigue</p> Signup and view all the answers

    Which of the following medications is an inhibitor of phosphodiesterase Type II?

    <p>Milrinone</p> Signup and view all the answers

    What is the mechanism of action of Loop Diuretics in reducing blood pressure?

    <p>Inhibition of Na+/K+/2Cl- cotransport system</p> Signup and view all the answers

    Which of the following medications is a Beta-1 selective blocker?

    <p>Bisoprolol</p> Signup and view all the answers

    What is the mechanism of action of Ivabradine in reducing heart rate?

    <p>Blockage of funny channel</p> Signup and view all the answers

    What is the common side effect of Angiotensin Receptor Neprilysin Inhibitors (ARNI) that is not seen with ACE inhibitors?

    <p>Phosphenes</p> Signup and view all the answers

    What is the mechanism of action of Cardiac Glycosides in increasing cardiac contractility?

    <p>Inhibition of Na+/K+ ATPase</p> Signup and view all the answers

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