ACE Inhibitors Mechanism of Action

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16 Questions

What is the primary mechanism by which ACE inhibitors decrease blood pressure?

Vasodilation leading to decreased total peripheral resistance

Which of the following is NOT a mechanism of action of ACE inhibitors?

Stimulation of the sympathetic nervous system

What is the most likely cause of dry cough in patients taking ACE inhibitors?

Increased bradykinin

Which of the following is a potential adverse effect of ACE inhibitors?

Hyperkalemia

What is the mechanism by which ACE inhibitors promote renal excretion of sodium and water?

Decreased release of aldosterone

Why may ACE inhibitors need to be changed to ARBs in some patients?

Due to dry cough

What is the mechanism of action of Angiotensin II Receptor Blockers (ARBs) in reducing blood pressure?

Blockage of AT1 receptors

Which of the following diuretics is a competitive antagonist of aldosterone receptors at distal tubule and collecting ducts?

Spironolactone

What is the mechanism of action of Sacubitril + Valsartan in reducing blood pressure?

Inhibition of neprilysin enzyme

What is the common side effect of beta-adrenoreceptor blockers that is not seen with ACE inhibitors?

Fatigue

Which of the following medications is an inhibitor of phosphodiesterase Type II?

Milrinone

What is the mechanism of action of Loop Diuretics in reducing blood pressure?

Inhibition of Na+/K+/2Cl- cotransport system

Which of the following medications is a Beta-1 selective blocker?

Bisoprolol

What is the mechanism of action of Ivabradine in reducing heart rate?

Blockage of funny channel

What is the common side effect of Angiotensin Receptor Neprilysin Inhibitors (ARNI) that is not seen with ACE inhibitors?

Phosphenes

What is the mechanism of action of Cardiac Glycosides in increasing cardiac contractility?

Inhibition of Na+/K+ ATPase

This quiz covers the site of action and mechanism of action of ACE inhibitors, including their effects on the renin-angiotensin system and blood pressure regulation.

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