Accessible Surface Area (ASA) and Solvent-Accessible Surface Area (SASA) Quiz
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Questions and Answers

What does ASA stand for in the context of biomolecules?

  • Angular Solvent Accessibility
  • Assigned Structural Analysis
  • Accessible Surface Area (correct)
  • Atomic Surface Area

    • In what units is ASA typically measured?

  • Cubic nanometers
  • Square micrometers
  • Square angstroms (correct)
  • Cubic centimeters

    • What is the principle behind the 'rolling ball' algorithm used for calculating ASA?

  • Utilizing a sphere of a particular radius to probe the surface of the molecule (correct)
  • Using a fixed grid to map the molecule's surface
  • Applying a solvent sphere to measure electrical charge distribution
  • Computing the area based on the molecule's chemical bonds

    • What does the Shrake–Rupley algorithm use to determine the surface area of a molecule?

    <p>The number of points equidistant from each atom that are solvent accessible (B)</p> Signup and view all the answers

    Who first described ASA and in what year?

    <p>Lee &amp; Richards in 1971 (D)</p> Signup and view all the answers

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