Absorption of Drugs Quiz
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Questions and Answers

Which protein is the main drug binding protein in plasma?

  • Hemoglobin
  • Albumin (correct)
  • Globulin
  • Fibrinogen
  • Which of the following factors related to the drug affects absorption the most?

  • Valency
  • Solubility (correct)
  • Ionization
  • Form
  • Which organ is the main site for excretion?

  • Gastrointestinal tract
  • Lungs
  • Kidney (correct)
  • Skin glands
  • Which type of drugs can pass through the blood-brain barrier?

    <p>Lipid-soluble, less-ionized drugs (B)</p> Signup and view all the answers

    Which of the following factors affects oral absorption of drugs the least?

    <p>State of systemic circulation (A)</p> Signup and view all the answers

    What effect does alkalinization of urine have on the excretion of acidic drugs?

    <p>It increases excretion (A)</p> Signup and view all the answers

    Which of the following drinks increases absorption of other drugs?

    <p>Tea (B)</p> Signup and view all the answers

    What is plasma half-life?

    <p>The time needed for the body to decrease the drug concentration to its half (B)</p> Signup and view all the answers

    Which phase of metabolism includes conjugation with glucuronic acid?

    <p>Phase II (B)</p> Signup and view all the answers

    Flashcards

    Main plasma drug-binding protein

    Albumin is the primary protein in blood plasma that binds to drugs.

    Factor most affecting drug absorption

    Drug solubility significantly impacts how quickly and efficiently a drug is absorbed.

    Main excretion organ

    The kidney is the primary organ responsible for eliminating drugs from the body.

    BBB-passing drug type

    Lipid-soluble and less-ionized drugs can easily cross the blood-brain barrier.

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    Factor least affecting oral absorption?

    The state of systemic circulation (blood flow) has the weakest effect on oral drug absorption.

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    Urine alkalinization impact on acidic drugs

    Making urine more alkaline increases the excretion of acidic drugs.

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    Drink enhancing drug absorption

    Tea can sometimes increase the absorption of other drugs, although more studies are needed.

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    Plasma half-life

    The time it takes for half the drug concentration in the bloodstream to decrease.

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    Phase II metabolism example

    Conjugation processes (like with glucuronic acid) are part of phase II metabolism.

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    Study Notes

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    Description

    Take this quiz to test your knowledge on the factors affecting the absorption of drugs. This quiz covers the factors related to the drug such as solubility, ionization, valency, and form, as well as the factors related to the patient such as the route of administration and the absorbing surface. Test your understanding of these key concepts and improve your knowledge in pharmacology.

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