Abnormalities of Chromosome Structure

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Questions and Answers

What is the result of failed homologous chromosomes recombination during meiosis I?

  • Chromosome missegregation (correct)
  • Normal chromosomal combination
  • Chromosomal structural rearrangements
  • Genome instability in cancer

What type of chromosomal structural rearrangement results in a gain or loss of genetic material?

  • Balanced inversion
  • Unbalanced rearrangement (correct)
  • Unbalanced inversion
  • Balanced translocation

What is the term for a chromosome with two identical arms?

  • Isochromosome (correct)
  • Monosomy
  • Translocation
  • Trisomy

What is the term for a chromosomal structural rearrangement involving a change in the orientation of a segment of a chromosome?

<p>Inversion (C)</p> Signup and view all the answers

What is the term for a chromosomal abnormality where a person has an extra copy of a particular chromosome?

<p>Trisomy (C)</p> Signup and view all the answers

What is the name of the process in which the chromosome number is reduced by half in meiosis?

<p>Meiosis I (B)</p> Signup and view all the answers

During which stage of meiosis do homologous chromosomes synapse?

<p>Zygotene (D)</p> Signup and view all the answers

What is the percentage of the genome that actually encodes proteins?

<p>Less than 1.5% (C)</p> Signup and view all the answers

What is the result of an isochromosome?

<p>Partial trisomy and partial monosomy (A)</p> Signup and view all the answers

What is the term for the condition where there is an extra copy of a part of a chromosome?

<p>Trisomy (A)</p> Signup and view all the answers

What is the main component of functional centromeres and forms the main structural constituent of heterochromatin?

<p>Satellite DNA (B)</p> Signup and view all the answers

What type of translocation involves the exchange of segments between two non-homologous chromosomes?

<p>Reciprocal translocation (A)</p> Signup and view all the answers

What is the outcome of mitosis in somatic cells?

<p>Diploid cells (B)</p> Signup and view all the answers

What is the term for the loss of part of a chromosome?

<p>Monosomy (C)</p> Signup and view all the answers

What is the term for a chromosomal abnormality where a segment of a chromosome breaks off and reattaches to the same chromosome, but in reverse order?

<p>Inversion (D)</p> Signup and view all the answers

What is the result of a duplication of a chromosome segment?

<p>Partial trisomy (B)</p> Signup and view all the answers

What is the consequence of having a single copy of genetic material that normally requires two copies to function?

<p>Haploinsufficiency (B)</p> Signup and view all the answers

What is the term for the loss of a chromosome segment, causing a chromosome imbalance?

<p>Deletion (C)</p> Signup and view all the answers

What is the result of a deletion of a chromosome segment?

<p>Partial monosomy (B)</p> Signup and view all the answers

What is the term for a chromosome with a deletion at the end of a chromosome?

<p>Terminal deletion (D)</p> Signup and view all the answers

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