30 Questions
What are apurinic / depurinic and apyrimidinic / depyrimidinic sites?
Locations in DNA that have neither purine nor pyrimidine bases
How are abasic sites repaired?
Base excision repair
What recognizes the error in an abasic site?
Abasic site specific protein
What is the function of an endonuclease in repairing an abasic site?
To cut the DNA strand flanking abasic site
What degrades the small stretch of nucleases cut by endonuclease in repairing an abasic site?
Exonuclease
What fills the gap with DNA in repairing an abasic site?
DNA polymerase
What seals the nick in repairing an abasic site?
Ligase
What is the alternative name for apurinic / depurinic and apyrimidinic / depyrimidinic sites?
Abasic site
What is the repair pathway used for abasic sites?
Base excision repair
What happens to the DNA strand flanking an abasic site during the repair process?
It is cut by endonuclease
What are apurinic / depurinic and apyrimidinic / depyrimidinic sites?
Locations in DNA that have neither purine nor pyrimidine bases
How are abasic sites repaired?
Base excision repair
What recognizes the error in an abasic site?
Abasic site specific protein
What is the function of an endonuclease in repairing an abasic site?
To cut the DNA strand flanking abasic site
What degrades the small stretch of nucleases cut by endonuclease in repairing an abasic site?
Exonuclease
What fills the gap with DNA in repairing an abasic site?
DNA polymerase
What seals the nick in repairing an abasic site?
Ligase
What is the alternative name for apurinic / depurinic and apyrimidinic / depyrimidinic sites?
Abasic site
What is the repair pathway used for abasic sites?
Base excision repair
What happens to the DNA strand flanking an abasic site during the repair process?
It is cut by endonuclease
What is an abasic site?
A location in DNA that has neither purine nor pyrimidine bases
How are abasic sites repaired?
Through the base excision repair pathway
What recognizes the abasic site error?
Abasic site specific protein
What is the role of endonuclease in repairing abasic sites?
It cuts the DNA strand flanking the abasic site
What is the role of exonuclease in repairing abasic sites?
It degrades the small stretch of nucleases cut by endonuclease
What is the role of DNA polymerase in repairing abasic sites?
It fills the gap with DNA
What is the role of ligase in repairing abasic sites?
It seals the nick
Which repair pathway is used to repair abasic sites?
Base excision repair pathway
What recognizes the error at the abasic site?
Abasic site specific protein
What is the term used to describe the location in DNA that has neither a purine nor a pyrimidine bases?
Abasic site
Test your knowledge on DNA repair by taking our quiz on abasic sites and the base excision repair pathways. Learn about the role of abasic site specific proteins, endonucleases, and exonucleases in repairing these sites. Challenge yourself with questions on this important aspect of DNA maintenance and improve your understanding of this fundamental biological process.
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