Abasic Sites and Base Excision Repair Quiz
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Questions and Answers

What are apurinic / depurinic and apyrimidinic / depyrimidinic sites?

  • Locations in DNA that have both purine and pyrimidine bases
  • Locations in DNA that have either purine or pyrimidine bases
  • Locations in DNA that have neither purine nor pyrimidine bases (correct)
  • Locations in DNA that have only pyrimidine bases

    • How are abasic sites repaired?

  • Mismatch repair
  • Nucleotide excision repair
  • Homologous recombination
  • Base excision repair (correct)

    • What recognizes the error in an abasic site?

  • Abasic site specific protein (correct)
  • Ligase
  • DNA polymerase
  • Endonuclease

    • What is the function of an endonuclease in repairing an abasic site?

    <p>To cut the DNA strand flanking abasic site</p> Signup and view all the answers

    What degrades the small stretch of nucleases cut by endonuclease in repairing an abasic site?

    <p>Exonuclease</p> Signup and view all the answers

    What fills the gap with DNA in repairing an abasic site?

    <p>DNA polymerase</p> Signup and view all the answers

    What seals the nick in repairing an abasic site?

    <p>Ligase</p> Signup and view all the answers

    What is the alternative name for apurinic / depurinic and apyrimidinic / depyrimidinic sites?

    <p>Abasic site</p> Signup and view all the answers

    What is the repair pathway used for abasic sites?

    <p>Base excision repair</p> Signup and view all the answers

    What happens to the DNA strand flanking an abasic site during the repair process?

    <p>It is cut by endonuclease</p> Signup and view all the answers

    What are apurinic / depurinic and apyrimidinic / depyrimidinic sites?

    <p>Locations in DNA that have neither purine nor pyrimidine bases</p> Signup and view all the answers

    How are abasic sites repaired?

    <p>Base excision repair</p> Signup and view all the answers

    What recognizes the error in an abasic site?

    <p>Abasic site specific protein</p> Signup and view all the answers

    What is the function of an endonuclease in repairing an abasic site?

    <p>To cut the DNA strand flanking abasic site</p> Signup and view all the answers

    What degrades the small stretch of nucleases cut by endonuclease in repairing an abasic site?

    <p>Exonuclease</p> Signup and view all the answers

    What fills the gap with DNA in repairing an abasic site?

    <p>DNA polymerase</p> Signup and view all the answers

    What seals the nick in repairing an abasic site?

    <p>Ligase</p> Signup and view all the answers

    What is the alternative name for apurinic / depurinic and apyrimidinic / depyrimidinic sites?

    <p>Abasic site</p> Signup and view all the answers

    What is the repair pathway used for abasic sites?

    <p>Base excision repair</p> Signup and view all the answers

    What happens to the DNA strand flanking an abasic site during the repair process?

    <p>It is cut by endonuclease</p> Signup and view all the answers

    What is an abasic site?

    <p>A location in DNA that has neither purine nor pyrimidine bases</p> Signup and view all the answers

    How are abasic sites repaired?

    <p>Through the base excision repair pathway</p> Signup and view all the answers

    What recognizes the abasic site error?

    <p>Abasic site specific protein</p> Signup and view all the answers

    What is the role of endonuclease in repairing abasic sites?

    <p>It cuts the DNA strand flanking the abasic site</p> Signup and view all the answers

    What is the role of exonuclease in repairing abasic sites?

    <p>It degrades the small stretch of nucleases cut by endonuclease</p> Signup and view all the answers

    What is the role of DNA polymerase in repairing abasic sites?

    <p>It fills the gap with DNA</p> Signup and view all the answers

    What is the role of ligase in repairing abasic sites?

    <p>It seals the nick</p> Signup and view all the answers

    Which repair pathway is used to repair abasic sites?

    <p>Base excision repair pathway</p> Signup and view all the answers

    What recognizes the error at the abasic site?

    <p>Abasic site specific protein</p> Signup and view all the answers

    What is the term used to describe the location in DNA that has neither a purine nor a pyrimidine bases?

    <p>Abasic site</p> Signup and view all the answers

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