Abasic Sites and Base Excision Repair Quiz
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Questions and Answers

What are apurinic / depurinic and apyrimidinic / depyrimidinic sites?

  • Locations in DNA that have both purine and pyrimidine bases
  • Locations in DNA that have either purine or pyrimidine bases
  • Locations in DNA that have neither purine nor pyrimidine bases (correct)
  • Locations in DNA that have only pyrimidine bases

How are abasic sites repaired?

  • Mismatch repair
  • Nucleotide excision repair
  • Homologous recombination
  • Base excision repair (correct)

What recognizes the error in an abasic site?

  • Abasic site specific protein (correct)
  • Ligase
  • DNA polymerase
  • Endonuclease

What is the function of an endonuclease in repairing an abasic site?

<p>To cut the DNA strand flanking abasic site (D)</p> Signup and view all the answers

What degrades the small stretch of nucleases cut by endonuclease in repairing an abasic site?

<p>Exonuclease (D)</p> Signup and view all the answers

What fills the gap with DNA in repairing an abasic site?

<p>DNA polymerase (A)</p> Signup and view all the answers

What seals the nick in repairing an abasic site?

<p>Ligase (D)</p> Signup and view all the answers

What is the alternative name for apurinic / depurinic and apyrimidinic / depyrimidinic sites?

<p>Abasic site (D)</p> Signup and view all the answers

What is the repair pathway used for abasic sites?

<p>Base excision repair (C)</p> Signup and view all the answers

What happens to the DNA strand flanking an abasic site during the repair process?

<p>It is cut by endonuclease (C)</p> Signup and view all the answers

What are apurinic / depurinic and apyrimidinic / depyrimidinic sites?

<p>Locations in DNA that have neither purine nor pyrimidine bases (C)</p> Signup and view all the answers

How are abasic sites repaired?

<p>Base excision repair (D)</p> Signup and view all the answers

What recognizes the error in an abasic site?

<p>Abasic site specific protein (C)</p> Signup and view all the answers

What is the function of an endonuclease in repairing an abasic site?

<p>To cut the DNA strand flanking abasic site (A)</p> Signup and view all the answers

What degrades the small stretch of nucleases cut by endonuclease in repairing an abasic site?

<p>Exonuclease (C)</p> Signup and view all the answers

What fills the gap with DNA in repairing an abasic site?

<p>DNA polymerase (D)</p> Signup and view all the answers

What seals the nick in repairing an abasic site?

<p>Ligase (B)</p> Signup and view all the answers

What is the alternative name for apurinic / depurinic and apyrimidinic / depyrimidinic sites?

<p>Abasic site (C)</p> Signup and view all the answers

What is the repair pathway used for abasic sites?

<p>Base excision repair (D)</p> Signup and view all the answers

What happens to the DNA strand flanking an abasic site during the repair process?

<p>It is cut by endonuclease (C)</p> Signup and view all the answers

What is an abasic site?

<p>A location in DNA that has neither purine nor pyrimidine bases (B)</p> Signup and view all the answers

How are abasic sites repaired?

<p>Through the base excision repair pathway (C)</p> Signup and view all the answers

What recognizes the abasic site error?

<p>Abasic site specific protein (C)</p> Signup and view all the answers

What is the role of endonuclease in repairing abasic sites?

<p>It cuts the DNA strand flanking the abasic site (D)</p> Signup and view all the answers

What is the role of exonuclease in repairing abasic sites?

<p>It degrades the small stretch of nucleases cut by endonuclease (D)</p> Signup and view all the answers

What is the role of DNA polymerase in repairing abasic sites?

<p>It fills the gap with DNA (A)</p> Signup and view all the answers

What is the role of ligase in repairing abasic sites?

<p>It seals the nick (C)</p> Signup and view all the answers

Which repair pathway is used to repair abasic sites?

<p>Base excision repair pathway (C)</p> Signup and view all the answers

What recognizes the error at the abasic site?

<p>Abasic site specific protein (B)</p> Signup and view all the answers

What is the term used to describe the location in DNA that has neither a purine nor a pyrimidine bases?

<p>Abasic site (D)</p> Signup and view all the answers

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