CPC - Dermatology

Interface dermatitis is associated with degenerating and necrotic keratinocytes

Interface dermatitis is an accumulation of dense, continuous infiltrate of lymphocytes along the dermo-epidermal junction

Two types of Panniculitis

The necrosis of adipocytes

Langhans type multinucleated giant cells are cells with centrally located nuclei shaped like a horse shoe.

An uncommon inflammatory disorder with alterations on the subcutaneous fat tissue

What is TRUE about Erythema induratum, Bazin type?

Two variants of Erythema Induratum

A inflammatory pattern characterized by basal layer vacuolization and a band of inflammation covering the dermal-epidermal junction

Subcutaneous tissue inflammation

TRUE about Erythema induratum

Erythema induratum manifests nodules that do not form plaques

Skin lesions in Erythema induratum often recur over the years

Histopathological features of Erythema induratum

Fat necrosis presents as pale adipocytes and absent nuclei

A group of disorders associated with tuberculosis which are immune reactions within the skin due to the hematogenous dissemination of the M. tuberculosis or another source like an individual with strong anti-tuberculous cell-mediated immunity

The pathogenesis of Erythema induratum is postulated to be a result of one type of hypersensitivity reaction

Postulated pathogenesis of Erythema induratum

In this particular hypersensitivity reaction, they cause tissue damage by eliciting inflammation at the sites of deposition

Types of T-cells responsible for type IV (delayed) hypersensitivity reaction