37 Questions
Which of the following best describes serous inflammation?
Inflammation marked by the exudation of cell-poor fluid into spaces created by injury to surface epithelia or body cavities
What is the fluid in serous inflammation typically like?
Cell-poor and not infected by destructive organisms
What is the term for the accumulation of fluid in body cavities?
Effusion
Which conditions can cause effusions consisting of transudates?
Reduced blood outflow in heart failure
What does a skin blister resulting from a burn or viral infection represent?
Accumulation of cell-poor fluid within the damaged epidermis
Which body cavities can be affected by serous inflammation?
Peritoneum, pleura, and pericardium
Which of the following is true about fibrinous exudate?
It can be dissolved by fibrinolysis and cleared by macrophages
What is the histological appearance of fibrin in a fibrinous exudate?
Eosinophilic meshwork of threads
What can happen if fibrin is not removed from a fibrinous exudate?
It can lead to the formation of scar tissue
What does the conversion of fibrinous exudate to scar tissue lead to?
Opaque fibrous thickening of the pericardium
Which body cavities are commonly affected by fibrinous inflammation?
Pleural cavity
What triggers the development of a fibrinous exudate in inflammation? (2 ans)
Large leaks in the blood vessels
How is a fibrinous exudate cleared from the site of inflammation?
Fibrinolysis by macrophages
Which of the following is the most common cause of purulent inflammation?
Bacterial infection
What is the main component of pus in purulent inflammation?
Neutrophils
What are abscesses?
Localized collections of pus
What is the central region of an abscess composed of?
Necrotic leukocytes and tissue cells
What may happen to an abscess over time?
It may become walled off and replaced by connective tissue
What is the main characteristic of purulent inflammation?
Production of pus, consisting of neutrophils and liquefied debris
What is the primary cause of purulent (suppurative) inflammation?
Infection with pyogenic (pus-producing) bacteria
What is the typical histological appearance outside the central region of an abscess?
Fibroblastic proliferation and vascular dilation
What is the recommended approach for persistent or critical abscesses?
Surgical drainage
What is the most common location for ulcers to occur?
Stomach
What is the main cause of ulcers in the skin and subcutaneous tissue of the lower extremities in older persons?
Circulatory disturbances
Which type of inflammation is often present in ulcers?
Both acute and chronic inflammation
What is the characteristic histological appearance of ulcers during the acute stage?
Polymorphonuclear infiltration and vascular dilation
What happens to the margins and base of an ulcer with chronicity?
Fibroblast proliferation
What is an ulcer?
A local defect or excavation of the organ or tissue surface
Which of the following is NOT one of the outcomes of acute inflammation?
Formation of abscesses
What is the usual outcome when the injury is limited or short-lived and there has been little tissue destruction?
Complete resolution
When does healing by connective tissue replacement occur?
After substantial tissue destruction
What happens during healing by connective tissue replacement?
Connective tissue grows into the area of damage or exudate
When does the acute inflammatory response progress to chronic inflammation?
When it cannot be resolved
What is the process involved in resolution of acute inflammation?
Removal of cellular debris and microbes by macrophages
What is the outcome of resolution of acute inflammation?
Restoration of the site of acute inflammation to normal
What are the variables that may modify the basic process of inflammation?
All of the above
What is the main process involved in the resorption of edema fluid in the resolution of acute inflammation?
Lymphatic drainage
Test your knowledge on the morphologic patterns of acute inflammation, specifically focusing on serous inflammation. Learn about the characteristics and exudation of cell-poor fluid in this type of inflammation.
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