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Questions and Answers
During which phase of an action potential in cardiac muscle do Ca2+ channels remain open?
During which phase of an action potential in cardiac muscle do Ca2+ channels remain open?
What is the primary role of the sinoatrial node in the heart?
What is the primary role of the sinoatrial node in the heart?
Which wave in an electrocardiogram (ECG) represents the depolarization of the ventricles?
Which wave in an electrocardiogram (ECG) represents the depolarization of the ventricles?
What is the function of the AV node in the heart's electrical conduction system?
What is the function of the AV node in the heart's electrical conduction system?
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Which of the following best describes the cardiac cycle?
Which of the following best describes the cardiac cycle?
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What causes the prolonged action potential duration in cardiac muscle compared to skeletal muscle?
What causes the prolonged action potential duration in cardiac muscle compared to skeletal muscle?
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What does the T wave in an ECG indicate?
What does the T wave in an ECG indicate?
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Which component of the cardiac conduction system follows the AV node?
Which component of the cardiac conduction system follows the AV node?
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What is the primary function of the systemic circuit?
What is the primary function of the systemic circuit?
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What opens into the aorta?
What opens into the aorta?
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Which structure of the heart is primarily responsible for pumping blood to the body?
Which structure of the heart is primarily responsible for pumping blood to the body?
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Which valves are involved in the blood flow from the left atrium to the left ventricle?
Which valves are involved in the blood flow from the left atrium to the left ventricle?
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Which artery supplies blood to the right ventricle?
Which artery supplies blood to the right ventricle?
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Where do the coronary arteries originate?
Where do the coronary arteries originate?
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After entering the left atrium, blood is received from which vessels?
After entering the left atrium, blood is received from which vessels?
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What is the nature of blood carried by the aorta?
What is the nature of blood carried by the aorta?
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Which structure separates the right and left atria?
Which structure separates the right and left atria?
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What distinguishes the ventricles from the atria in terms of structure and function?
What distinguishes the ventricles from the atria in terms of structure and function?
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What is the primary function of the atrioventricular valves?
What is the primary function of the atrioventricular valves?
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Which feature is characteristic of cardiac muscle tissue?
Which feature is characteristic of cardiac muscle tissue?
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Which phase of the cardiac cycle is characterized by the contraction of the ventricles?
Which phase of the cardiac cycle is characterized by the contraction of the ventricles?
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What is the main purpose of the coronary sulcus in the heart?
What is the main purpose of the coronary sulcus in the heart?
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Which of the following statements about cardiac electrical conduction is true?
Which of the following statements about cardiac electrical conduction is true?
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What role do valves play in the heart's functioning?
What role do valves play in the heart's functioning?
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Study Notes
Cardiac Action Potentials
- Depolarization: Sodium (Na+) and Calcium (Ca2+) channels open, allowing ions to enter the cell.
- Plateau: Sodium (Na+) channels close, some Potassium (K+) channels open, and Calcium (Ca2+) channels remain open, prolonging the action potential.
- Repolarization: Potassium (K+) channels are open, Calcium (Ca2+) channels close, allowing potassium to exit the cell.
- Duration: Action potentials in cardiac muscle last significantly longer (200-500 msec) compared to skeletal muscle (2 msec) due to the plateau phase.
Cardiac Conduction System
- Function: Conducts electrical impulses throughout the heart, coordinating the contraction of atria and ventricles.
- Sinoatrial Node (SA Node): Located in the right atrium, initiates action potentials, acts as the heart's pacemaker, and contains a large number of Calcium (Ca2+) channels.
Path of Action Potential Through the Heart
- SA node
- AV node (Atrioventricular)
- AV bundle
- Right and Left Bundle Branches
- Purkinje Fibers
Electrocardiogram (ECG/EKG)
- Purpose: Records electrical activity of the heart, diagnoses cardiac abnormalities, and uses electrodes to measure electrical changes.
-
Components:
- P Wave: Depolarization of the atria.
- QRS Complex: Depolarization of the ventricles.
- T Wave: Repolarization of the ventricles.
Left Side of the Heart
- Systemic Circuit: Carries oxygen-rich blood from the heart to the body.
Left Atrium
- Receives oxygen-rich blood from the lungs through four pulmonary veins.
Left Ventricle
- Pumps oxygen-rich blood to the aorta to the body.
- Has a thicker wall and contracts more forcefully than the right ventricle to overcome higher pressure in the systemic circuit.
Aorta
- Carries oxygen-rich blood from the left ventricle to the rest of the body.
Blood Flow Through the Heart
- Right Atrium (RA)
- Tricuspid Valve
- Right Ventricle (RV)
- Pulmonary Semilunar Valve
- Pulmonary Trunk
- Pulmonary Arteries
- Lungs
- Pulmonary Veins
- Left Atrium (LA)
- Bicuspid Valve
- Left Ventricle (LV)
- Aortic Semilunar Valve
- Aorta
- Body
Blood Supply to the Heart
-
Coronary Arteries: Branch directly from the aorta, supplying blood to the heart wall.
- Left Coronary Artery: Branches to supply the anterior heart wall and the left ventricle.
- Right Coronary Artery: Supplies the right ventricle.
Cardiac Muscle
- Characteristics: Centrally located nucleus, branching cells, rich in mitochondria, striated with actin and myosin, uses Calcium (Ca2+) and ATP for contractions, and interconnected cells via intercalated disks.
Chambers and Blood Vessels
- Chambers: Left Atrium (LA), Right Atrium (RA), Left Ventricle (LV), and Right Ventricle (RV).
- Coronary Sulcus: Separates the atria from the ventricles.
Atria
- Upper portion of the heart, holding chambers.
- Small, thin-walled, and contract minimally to push blood into the ventricles.
- Interatrial Septum: Separates the right and left atria.
Ventricles
- Lower portion of the heart, pumping chambers
- Thick, strong-walled, and contract forcefully to propel blood out of the heart
- Interventricular Septum: Separates the right and left ventricles.
Heart Valves
- Function: Ensure one-way blood flow through the heart.
-
Atrioventricular Valves (AV): Located between the atria and ventricles.
- Tricuspid Valve: Located between the right atrium (RA) and right ventricle (RV), has three cusps.
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