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Which of the following statements about glycogen and its catabolism is NOT true?

The function of glycogen in liver is to supply glucose to the blood when needed

The function of glycogen in muscle is to supply energy for muscle contraction

When glycogenolysis is active in liver, glycolysis is usually inactive

Muscle, but not liver, has the enzyme glucose-6-phosphatase (correct)

In the liver, glucagon will activate

Glycolysis and glycogenolysis

Glycolysis and glycogen synthesi

Gluconeogenesis and glycogenolysis (correct)

Gluconeogenesis and glycogen synthase

When glycogenolysis occurs, all of the following occur in both liver and muscle EXCEPT:

Debranching enzyme catalyzes the hydrolysis of alpha-1,6-glycosidic bonds in glycogen

Glucose-1-P is converted to glucose-6-P by phosphoglucomutase

The conversion of glycogen phosphorylase a to glycogen phosphorylase b is a major control step

The glucose produced is exported to the body via the blood (correct)

. Which of the following statement is NOT true?

glycogenolysis is controlled by insulin (A) Signup and view all the answers

What is the main function of debranching enzyme?

both A and C (D) Signup and view all the answers

Which enzyme catalyzes the only reversible reaction of whole glycogen metabolism?

phosphoglucomutase (A) Signup and view all the answers

Why can’t muscle release glucose into blood?

absence of glucose-6-phosphatase (C) Signup and view all the answers

When glycogenolysis occurs, all of the following occur in both liver and muscle EXCEPT:

The glucose produced is exported to the body via the blood (D) Signup and view all the answers

Glycogen phosphorylase is responsible for the breakdown of glycogen to:

Glucose-1-phosphate (B) Signup and view all the answers

. In the glycogen synthase reaction, the precursor to glycogen is:

UDP-glucose (B) Signup and view all the answers

Why is glycogen branching important?

Both to increase solubility and to increase faster breakdown (C) Signup and view all the answers

All of the following statements about glycogen are true EXCEPT

C) Glycogen is stored in all cells (C) Signup and view all the answers

Which enzyme is considered as the principal enzyme for the regulation of glycogenolysis?

glycogen phosphorylase (B) Signup and view all the answers

Where does glycogenolysis takes place?

cytosol (A) Signup and view all the answers

The active form of glycogen synthase is:

de-phosphorylated (B) Signup and view all the answers

Which of the following statements about the control of glycogen synthase are correct? A) Glycogen synthase phosphorylation by glycogen synthase kinase 3 (GSK3) is favoured by insulin.

C) Glycogen synthase is activated by PP1 (protein phosphatase 1). (C) Signup and view all the answers

. In glycogen the chains are formed by ______ glycosidic linkages

both (C) Signup and view all the answers

Which of the following statements is NOT true about

glycogen synthase needs to be phosphorylated (D) Signup and view all the answers

All the following enzymes are involved in the synthesis of glycogen except:

C) Phosphofructokinase (C) Signup and view all the answers

Hexokinase in the liver is inhibited by high levels of Glucose-6- phosphate. Why?

Hexokinase IV is not inhibited by high levels of Glucose-6-phosphate (C) Signup and view all the answers

term 1 -week4/ 5

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Questions and Answers

Which of the following statements about glycogen and its catabolism is NOT true?

In the liver, glucagon will activate

When glycogenolysis occurs, all of the following occur in both liver and muscle EXCEPT:

. Which of the following statement is NOT true?

What is the main function of debranching enzyme?

Which enzyme catalyzes the only reversible reaction of whole glycogen metabolism?

Why can’t muscle release glucose into blood?

When glycogenolysis occurs, all of the following occur in both liver and muscle EXCEPT:

Glycogen phosphorylase is responsible for the breakdown of glycogen to:

. In the glycogen synthase reaction, the precursor to glycogen is:

Why is glycogen branching important?

All of the following statements about glycogen are true EXCEPT

Which enzyme is considered as the principal enzyme for the regulation of glycogenolysis?

Where does glycogenolysis takes place?

The active form of glycogen synthase is:

Which of the following statements about the control of glycogen synthase are correct? A) Glycogen synthase phosphorylation by glycogen synthase kinase 3 (GSK3) is favoured by insulin.

. In glycogen the chains are formed by ______ glycosidic linkages

Which of the following statements is NOT true about

All the following enzymes are involved in the synthesis of glycogen except:

Hexokinase in the liver is inhibited by high levels of Glucose-6- phosphate. Why?

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