20 Questions
Which of the following statements about glycogen and its catabolism is NOT true?
Muscle, but not liver, has the enzyme glucose-6-phosphatase
In the liver, glucagon will activate
Gluconeogenesis and glycogenolysis
- When glycogenolysis occurs, all of the following occur in both liver
and muscle EXCEPT:
The glucose produced is exported to the body via the blood
. Which of the following statement is NOT true?
glycogenolysis is controlled by insulin
What is the main function of debranching enzyme?
both A and C
Which enzyme catalyzes the only reversible reaction of whole glycogen metabolism?
phosphoglucomutase
Why can’t muscle release glucose into blood?
absence of glucose-6-phosphatase
When glycogenolysis occurs, all of the following occur in both liver and muscle EXCEPT:
The glucose produced is exported to the body via the blood
Glycogen phosphorylase is responsible for the breakdown of glycogen to:
Glucose-1-phosphate
. In the glycogen synthase reaction, the precursor to glycogen is:
UDP-glucose
Why is glycogen branching important?
Both to increase solubility and to increase faster breakdown
All of the following statements about glycogen are true EXCEPT
C) Glycogen is stored in all cells
Which enzyme is considered as the principal enzyme for the regulation of glycogenolysis?
glycogen phosphorylase
Where does glycogenolysis takes place?
cytosol
The active form of glycogen synthase is:
de-phosphorylated
Which of the following statements about the control of glycogen synthase are correct? A) Glycogen synthase phosphorylation by glycogen synthase kinase 3 (GSK3) is favoured by insulin.
C) Glycogen synthase is activated by PP1 (protein phosphatase 1).
. In glycogen the chains are formed by ______ glycosidic linkages
both
- Which of the following statements is NOT true about
glycogen synthase needs to be phosphorylated
- All the following enzymes are involved in the
synthesis of glycogen except:
C) Phosphofructokinase
Hexokinase in the liver is inhibited by high levels of Glucose-6- phosphate. Why?
Hexokinase IV is not inhibited by high levels of Glucose-6-phosphate
Test your knowledge of glycogen and its catabolism with this quiz. Answer questions about the functions of debranching enzyme, reversible reaction in glycogen metabolism, and the differences between liver and muscle glycogenolysis.
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