5 Stages of Fracture Healing Flashcards

Study Notes

Stage One: Fracture and Inflammatory Phase

Initial bleeding occurs between the edges of fractured bone.
A hematoma develops within the first few hours and days post-injury.
Inflammation increases vascular permeability and attracts white blood cells to the area.

Stage Two: Granulation Tissue Formation

This stage begins the healing process by forming granulation tissue.
Fibroblasts migrate to the injury site, leading to an extensive growth of vascular tissue.
A significant supply of nutrients and oxygen is crucial during the early stages and lasts approximately two weeks.

Stage Three: Callus Formation

Callus formation marks a critical healing phase of the fracture.
Osteoblasts and chondroblasts contribute to the formation of the callus.
The extracellular organic matrix of woven bone and cartilage starts to synthesize.
Newly formed mineralized bone emerges approximately within 4 to 15 weeks post-injury.

Stage Four: Lamellar Bone Deposition

This stage focuses on the strengthening of the bone through ossification.
The initially formed mesh-like callus is replaced by organized sheets of mineralized bone.
These sheets are aligned parallel to the bone's axis, enhancing mechanical strength compared to the original callus.

Stage Five: Bone Remodelling

The final stage of fracture healing where the bone is reshaped and refined.
Focuses on the adjustment of bone structure in response to mechanical stress and loading.
Ensures the restored bone is both functional and resilient.

Description

Test your knowledge on the five stages of fracture healing with these flashcards. Each card provides key terms and definitions to help you understand the healing process, from the inflammatory phase to granulation tissue formation. Perfect for students in healthcare or anatomy courses.