13 Questions
What is the main purpose of the 3Rs principles mentioned in the text?
To minimize the number of animals used in experiments
Who were the scientists involved in the project that led to the publication of 'Principles of Humane Experimental Techniques'?
Microbiologist R.L. Burch and Zoologist W.M.S. Russel
What is considered a prerequisite for successful animal experiments?
Treating animals humanely
Which of the following does NOT represent one of the 3Rs principles mentioned?
Increase the pain and distress of animals during experiments
When did the proposal for humane experimental techniques first surface?
1954
What does the term '3Rs' refer to in the context of animal experiments?
Replacement, Reduction, Replication
What is considered a method of 'full replacement' in animal experiments according to the text?
Organs-on-microchips
What is a major disadvantage mentioned in the text regarding in vitro systems as replacements in animal experiments?
Loss of organ structure & cell-cell interaction
What is the difference between 'Duplication' and 'Replication' in animal experiments as per the text?
'Duplication' is performed without scientific justification while 'Replication' is scientifically justified.
What does 'Reduction and Species Selection' focus on in animal experiments according to the text?
Gathering maximum information from each animal
Why is 'Experimental Design' highlighted as good scientific practice in animal experiments as per the text?
To ensure the validity of the experiment
Which organization awarded the Russell and Burch Award in 1990?
Humane Society of United States
'Liver on a chip' is an example of a method used for what purpose in animal experiments?
Partial replacement
Summary of a lecture by Dr. Abeer Mahmoud Badr on the 3Rs principles (Replacement, Reduction, Refinement) and the Animal Use Protocol. The lecture covers the proposal made in 1954 by Charles Hume, the study of humane techniques in laboratory animal experiments, and the publication of 'Principles of Humane Experimental Techniques' in 1959.
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