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Animal Research Ethics: 3Rs and ASPA
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Animal Research Ethics: 3Rs and ASPA

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Questions and Answers

What is the primary reason for not inflicting pain or suffering unnecessarily in animal research?

  • For ethical reasons and to avoid negative public perception (correct)
  • To reduce the cost of animal care and maintenance
  • To ensure the accuracy of scientific results
  • To comply with the 3R's principle
  • What is the main purpose of the Animal Scientific Procedures Act 1986?

  • To encourage the development of non-animal testing methods
  • To regulate and protect animals used in scientific procedures (correct)
  • To provide funding for animal research projects
  • To promote the use of animals in scientific studies
  • What is the status of humans under the Animal Scientific Procedures Act 1986?

  • They are protected under ASPA
  • They are exempt from ASPA (correct)
  • They are only protected during certain stages of development
  • They are not mentioned in ASPA
  • At what point are fish and amphibia protected under the Animal Scientific Procedures Act 1986?

    <p>Once they can feed independently</p> Signup and view all the answers

    Why might ASPA not apply to certain individuals or organizations?

    <p>Because they are not using animals for scientific purposes</p> Signup and view all the answers

    What is the primary reason for avoiding unnecessary pain and suffering in animal research?

    <p>To avoid changing the system being investigated</p> Signup and view all the answers

    What is the minimum requirement for an animal to be considered for re-homing?

    <p>The animal must be in good health and pose no human health risks</p> Signup and view all the answers

    What is the maximum level of pain, suffering, or distress that a procedure can cause before it is classified as severe?

    <p>Long-lasting severe pain, suffering, or distress</p> Signup and view all the answers

    What is the purpose of a Project Licence in animal research?

    <p>To outline the project goals and methods</p> Signup and view all the answers

    What is the main principle behind the 'Replacement' aspect of the 3R's in animal research?

    <p>Replacing animals with alternative models or methods</p> Signup and view all the answers

    What is the fate of an animal that has undergone a 'non-recovery' procedure?

    <p>The animal is humanely killed after the procedure</p> Signup and view all the answers

    Study Notes

    Ethics in Animal Research

    • Unnecessary infliction of pain or suffering is avoided for ethical reasons and to maintain a positive public image of research.

    The 3Rs in Animal Research

    • Reduction: minimize the number of animals used
    • Refinement: minimize suffering and improve animal welfare
    • Replacement: replace animals with alternative methods or models

    Animal Scientific Procedures Act (ASPA) 1986

    • Legislation protecting animals used in scientific studies
    • Applies to the use of animals for scientific purposes, not for non-scientific reasons

    Protected Animals

    • All living vertebrates, except humans
    • Cephalopods (e.g., octopuses, squids)
    • Fish and amphibians: protected once they can feed independently
    • Cephalopods: protected from the point of hatching
    • Embryonic and foetal forms of mammals, birds, and reptiles: protected during the last third of gestation or incubation

    Procedure Classifications

    • Regulated procedure: equivalent to or greater than the pain caused by inserting a hypodermic needle
    • Non-recovery: procedure under general anesthesia from which the animal will not recover consciousness
    • Mild: short-term mild pain, suffering, or distress
    • Moderate: short-term moderate pain, suffering, or distress, or long-lasting mild pain, suffering, or distress
    • Severe: severe pain, suffering, or distress, or long-lasting moderate pain, suffering, or distress

    Licensing

    • Project licence: outlines project goals, methods, locations, number of animals, and types of regulated procedures
    • Personal licence: outlines individual permissions within a project

    Animal Fates

    • Humanely killed
    • Re-used (only if same results cannot be obtained from a naive animal)
    • Re-homed (must be in good health, pose no human health risks, and have undergone an approved socialisation scheme)
    • Setting free

    Penalties for Non-Compliance

    • Temporary withdrawal of licence
    • Permanent withdrawal of licence
    • Financial penalty
    • Jail sentence

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    Description

    Learn about the principles guiding animal research, including the 3Rs of Reduction, Refinement, and Replacement, and the Animal Scientific Procedures Act 1986 (ASPA) that regulates animal use in scientific studies and testing. Understand the importance of ethical considerations in animal research and testing.

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