DNA and RNA Synthesis

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Which Topoisomerase requires energy?

Topoisomerase I

Topoisomerase II (correct)

Topoisomerase III

Topoisomerase IV

RNA synthesis is known as

Transcription (correct)

Translation

Replication

Encoding

The purpose of single-strand DNA binding proteins like replication protein A is to

denature DNA making a replication "bubble"

Denature helix ahead of replication

keep single strand template open (correct)

Join Okazaki fragments

What polymerase replaces DNA polymerase alpha and replicates the leading strand?

Polymerase Epsilon Signup and view all the answers

What polymerase replaces DNA polymerase alpha and replicates the lagging strand?

Polymerase Delta Signup and view all the answers

Errors that escape proofreading are corrected by

Mismatch repair enzymes Signup and view all the answers

Base Excision Repair removes ___

Abnormal bases Signup and view all the answers

Each time a chromosome divides its telomere gets shorter. Short telomeres causes cellular _____

senescence Signup and view all the answers

What solves the end replication problem

Telomerase Signup and view all the answers

The promoter's function is the same in prokaryotes as it is in eukaryotes. That is it defines the Transcription Start Site, defines which DNA strand is the template, and the direction of transcription.

True Signup and view all the answers

RNA Polymerase terminates RNA synthesis when the newly made RNA folds into a

hairpin Signup and view all the answers

All three RNA polymerases (I,II,III) are sensitive and can be inhibited by

Actinomycin D Signup and view all the answers

Rifampin, a first-line antibiotic against TB, is able to bind eukaryotic RNA polymerases.

False Signup and view all the answers

The purpose of the Sigma factor is to help bacterial RNA polymerase recognize the promoter

True Signup and view all the answers

All RNAs require post-transcriptional processing

True Signup and view all the answers

After RNA pol I transcribes, RNases cut the precursor into 3 rRNAs. These are then exported to the cytoplasm. Why?

Because ribosomes are in the cytoplasm Signup and view all the answers

Nucleotidyl transferase adds CCA to

3' end Signup and view all the answers

Only RNA polymerase ___ transcripts are capped

II Signup and view all the answers

Abnormal hemoglobin in severe β(beta)- thalassemia caused by

splice site mutation Signup and view all the answers

splicing removes ____

introns Signup and view all the answers

A 7-methylguanosine-triphosphate cap protects the

5' end of eukaryotic mRNAs Signup and view all the answers

DNA and RNA Synthesis

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Questions and Answers

Which Topoisomerase requires energy?

RNA synthesis is known as

The purpose of single-strand DNA binding proteins like replication protein A is to

What polymerase replaces DNA polymerase alpha and replicates the leading strand?

What polymerase replaces DNA polymerase alpha and replicates the lagging strand?

Errors that escape proofreading are corrected by

Base Excision Repair removes ___

Each time a chromosome divides its telomere gets shorter. Short telomeres causes cellular _____

What solves the end replication problem

The promoter's function is the same in prokaryotes as it is in eukaryotes. That is it defines the Transcription Start Site, defines which DNA strand is the template, and the direction of transcription.

RNA Polymerase terminates RNA synthesis when the newly made RNA folds into a

All three RNA polymerases (I,II,III) are sensitive and can be inhibited by

Rifampin, a first-line antibiotic against TB, is able to bind eukaryotic RNA polymerases.

The purpose of the Sigma factor is to help bacterial RNA polymerase recognize the promoter

All RNAs require post-transcriptional processing

After RNA pol I transcribes, RNases cut the precursor into 3 rRNAs. These are then exported to the cytoplasm. Why?

Nucleotidyl transferase adds CCA to

Only RNA polymerase ___ transcripts are capped

Abnormal hemoglobin in severe β(beta)- thalassemia caused by

splicing removes ____

A 7-methylguanosine-triphosphate cap protects the

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