Podcast
Questions and Answers
What is the role of nucleoside analogs in blocking DNA replication?
What is the role of nucleoside analogs in blocking DNA replication?
- They slow the division of rapidly growing cells and viruses by promoting DNA replication
- They block DNA replication by inhibiting the incorporation of certain nucleoside analogs (correct)
- They have no impact on DNA replication or cell division
- They enhance DNA chain growth by incorporating modified nucleosides
Which of the following is a correct statement about topoisomerase inhibitors?
Which of the following is a correct statement about topoisomerase inhibitors?
- Fluoroquinolones are used as antibiotics to inhibit prokaryotic topoisomerase II (correct)
- Nalidixic acid and ciprofloxacin are used as anti-cancer treatments to inhibit eukaryotic topoisomerase II
- Daunorubicin and doxorubicin are used as antiviral agents to inhibit prokaryotic topoisomerase II
- Etoposide and teniposide are used as antibiotics to inhibit eukaryotic topoisomerase II
Which nucleoside analog is used in HIV treatment?
Which nucleoside analog is used in HIV treatment?
- 2′,3′-dideoxyinosine ([ddI]) or didanosine
- Adenine arabinoside (araA)
- Cytosine arabinoside (araC)
- AZidoThymidine (AZT) or zidovudine (correct)
How are thymine dimers eliminated from DNA?
How are thymine dimers eliminated from DNA?
What pathology is associated with defective repair of thymidine dimers?
What pathology is associated with defective repair of thymidine dimers?
Which of the following is an inhibitor of eukaryotic topoisomerase II used in anti-cancer treatment?
Which of the following is an inhibitor of eukaryotic topoisomerase II used in anti-cancer treatment?
What modification in the sugar portion of the nucleoside can block DNA replication and slow the division of rapidly growing cells?
What modification in the sugar portion of the nucleoside can block DNA replication and slow the division of rapidly growing cells?
What is the genetic disease characterized by extreme sensitivity to sunlight, skin freckling, ulcerations, and skin cancer?
What is the genetic disease characterized by extreme sensitivity to sunlight, skin freckling, ulcerations, and skin cancer?
Which nucleoside analog is used as an antiviral agent against herpes?
Which nucleoside analog is used as an antiviral agent against herpes?
What is the role of fluoroquinolones such as ciprofloxacin?
What is the role of fluoroquinolones such as ciprofloxacin?
