2nd Year Clinical Bacteriology Antibacterial Drugs Quiz
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Questions and Answers

Which type of antibiotics stop bacterial growth but do not kill the bacteria?

  • Antibiotic resistant
  • Bactericidal
  • Bacteriolytic
  • Bacteriostatic (correct)
  • What is the mechanism of action of Rifampicin among the following choices?

  • DNA synthesis inhibition
  • Cell wall synthesis inhibition
  • Protein synthesis inhibition (correct)
  • Cell membrane disruption
  • In antimicrobial susceptibility testing, which type of antibiotic interaction results in one drug interfering with the activity of another?

  • Synergistic
  • Antagonistic (correct)
  • Indifferent
  • Additive
  • What is the purpose of testing antibiotic combinations?

    <p>For better treatment outcomes</p> Signup and view all the answers

    Which antibiotic is known for causing teeth staining and should not be given in excess?

    <p>Tetracycline</p> Signup and view all the answers

    What is the purpose of serially distributing the concentration of antibiotics in MACROBROTH / TUBE DM?

    <p>To create varying concentrations for different bacterial strains</p> Signup and view all the answers

    Which method employs boring holes onto agar for the diffusion of antibiotics?

    <p>AGAR CUP DIFFUSION METHOD</p> Signup and view all the answers

    What is the main difference between AGAR CYLINDER DIFFUSION METHOD and MICROTUBE DILUTION METHOD?

    <p>Method of dispensing antibiotics</p> Signup and view all the answers

    Which bacterium is represented by the code 29212 in the ATCC listing?

    <p>Enterococcus foecalis</p> Signup and view all the answers

    What is the purpose of using a tray with antibiotics and alamar Blue indicator in the ALAMAR SYSTEM?

    <p>To measure antibiotic susceptibility visually</p> Signup and view all the answers

    What is the standard inoculum size used in MACROBROTH / TUBE DM?

    <p>$5x10^5$ CFU/mL</p> Signup and view all the answers

    In the Kirby-Bauer disk diffusion test, standardized suspensions of organisms are inoculated onto which type of agar?

    <p>Mueller-Hinton agar</p> Signup and view all the answers

    What is the purpose of incubating the agar plate upside down during the Kirby-Bauer disk diffusion test?

    <p>To prevent the agar from drying out</p> Signup and view all the answers

    Which bacteria require incubation at 35°C for 16-18 hours during the Kirby-Bauer disk diffusion test?

    <p>Enterobacteriaceae</p> Signup and view all the answers

    What is used to standardize the pure inoculum in the Kirby-Bauer disk diffusion test?

    <p>Mcfarland standard</p> Signup and view all the answers

    How are antibiotic discs impregnated with paper discs transferred aseptically during the Kirby-Bauer disk diffusion test?

    <p>Using forceps with proper distance maintained between each disc</p> Signup and view all the answers

    How is antimicrobial susceptibility interpreted after measuring the zone of inhibition in the Kirby-Bauer disk diffusion test?

    <p>Using a ruler to measure in millimeters and comparing to CLSI table</p> Signup and view all the answers

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