23 Questions
What are the three major classes of lipoproteins found in serum?
LDL, HDL, and VLDL
Which classification of hyperlipoproteinemia is considered rare according to Fredrickson-LevyLees Classification?
Type I (chylomicrons)
What is the primary defect in familial hypercholesterolemia?
Inability to bind LDL to the LDL receptor
Which lipoprotein class is most common in Type IIb hyperlipoproteinemia?
LDL
What is the primary characteristic of plasma lipoproteins?
Spherical particles with phospholipid surfaces
Which lipoprotein class is associated with a predisposition to coronary, cerebrovascular, and peripheral vascular arterial disease?
LDL
Which of the following is used to identify groups of patients qualifying for treatment with statins?
Total cholesterol and statin benefit groups
At what age should the ten-year risk for ASCVD be calculated in patients without ASCVD or LDL-C ≥ 190 mg/dL?
40
For which group of patients can lifetime risk calculation be done?
Patients age 20–39 with 10-year risk < 7.5%
Which component is NOT included in the estimator for calculating risk?
Triglycerides
What is a primary purpose of the 2018 ACC/AHA Blood Cholesterol Guideline regarding statin therapy?
To reduce the 10-year risk of ASCVD in secondary intervention
What is the primary consequence of a lack of LDL degradation by cells?
Unregulated biosynthesis of cholesterol
Which condition is associated with hypertriglyceridemia?
Obesity
What is a secondary cause of hypocholesterolemia?
Malnutrition
Which drug class is associated with causing hypercholesterolemia?
Mirtazapine
What condition can lead to low HDL levels?
Myeloproliferative diseases
Which disease is NOT associated with an increase in triglyceride levels?
AIDS
What symptoms might symptomatic patients with dyslipidemia complain of?
Chest pain and palpitations
Which of the following signs may indicate dyslipidemia in a patient?
High BMI and high waist size
Which of the following laboratory test results are commonly elevated in dyslipidemia?
Elevations in total cholesterol, LDL, triglycerides
How often should adults 20 years of age or older have a fasting lipoprotein profile measurement according to the text?
Once every 5 years
Which equation can be used for calculating VLDL levels based on triglyceride values?
$VLDL = triglyceride/5$
What should be done if a nonfasted lipoprotein profile shows a total cholesterol ≥200 mg/dL or HDL-C <40 mg/dL?
Order a fasting lipoprotein profile for follow-up
Test your knowledge on the 2018 ACC/AHA Blood Cholesterol Guideline, including the components of the estimator and statin benefit groups identified in the guideline. Explore groups of patients who qualify for treatment with statins to reduce the 10-year risk of ASCVD.
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