2018 ACC/AHA Blood Cholesterol Guideline Quiz
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Questions and Answers

What are the three major classes of lipoproteins found in serum?

  • IDL, LDL, and VLDL
  • LDL, HDL, and VLDL (correct)
  • Chylomicrons, LDL, and HDL
  • Chylomicrons, IDL, and VLDL
  • Which classification of hyperlipoproteinemia is considered rare according to Fredrickson-LevyLees Classification?

  • Type IIa (LDL)
  • Type IIb (LDL + VLDL)
  • Type I (chylomicrons) (correct)
  • Type IV (VLDL)
  • What is the primary defect in familial hypercholesterolemia?

  • Inability to bind LDL to the LDL receptor (correct)
  • Overproduction of cholesterol
  • Deficiency of HDL cholesterol
  • Inability to bind VLDL to the receptor
  • Which lipoprotein class is most common in Type IIb hyperlipoproteinemia?

    <p>LDL</p> Signup and view all the answers

    What is the primary characteristic of plasma lipoproteins?

    <p>Spherical particles with phospholipid surfaces</p> Signup and view all the answers

    Which lipoprotein class is associated with a predisposition to coronary, cerebrovascular, and peripheral vascular arterial disease?

    <p>LDL</p> Signup and view all the answers

    Which of the following is used to identify groups of patients qualifying for treatment with statins?

    <p>Total cholesterol and statin benefit groups</p> Signup and view all the answers

    At what age should the ten-year risk for ASCVD be calculated in patients without ASCVD or LDL-C ≥ 190 mg/dL?

    <p>40</p> Signup and view all the answers

    For which group of patients can lifetime risk calculation be done?

    <p>Patients age 20–39 with 10-year risk &lt; 7.5%</p> Signup and view all the answers

    Which component is NOT included in the estimator for calculating risk?

    <p>Triglycerides</p> Signup and view all the answers

    What is a primary purpose of the 2018 ACC/AHA Blood Cholesterol Guideline regarding statin therapy?

    <p>To reduce the 10-year risk of ASCVD in secondary intervention</p> Signup and view all the answers

    What is the primary consequence of a lack of LDL degradation by cells?

    <p>Unregulated biosynthesis of cholesterol</p> Signup and view all the answers

    Which condition is associated with hypertriglyceridemia?

    <p>Obesity</p> Signup and view all the answers

    What is a secondary cause of hypocholesterolemia?

    <p>Malnutrition</p> Signup and view all the answers

    Which drug class is associated with causing hypercholesterolemia?

    <p>Mirtazapine</p> Signup and view all the answers

    What condition can lead to low HDL levels?

    <p>Myeloproliferative diseases</p> Signup and view all the answers

    Which disease is NOT associated with an increase in triglyceride levels?

    <p>AIDS</p> Signup and view all the answers

    What symptoms might symptomatic patients with dyslipidemia complain of?

    <p>Chest pain and palpitations</p> Signup and view all the answers

    Which of the following signs may indicate dyslipidemia in a patient?

    <p>High BMI and high waist size</p> Signup and view all the answers

    Which of the following laboratory test results are commonly elevated in dyslipidemia?

    <p>Elevations in total cholesterol, LDL, triglycerides</p> Signup and view all the answers

    How often should adults 20 years of age or older have a fasting lipoprotein profile measurement according to the text?

    <p>Once every 5 years</p> Signup and view all the answers

    Which equation can be used for calculating VLDL levels based on triglyceride values?

    <p>$VLDL = triglyceride/5$</p> Signup and view all the answers

    What should be done if a nonfasted lipoprotein profile shows a total cholesterol ≥200 mg/dL or HDL-C <40 mg/dL?

    <p>Order a fasting lipoprotein profile for follow-up</p> Signup and view all the answers

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