2018 ACC/AHA Blood Cholesterol Guideline Quiz
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Questions and Answers

What are the three major classes of lipoproteins found in serum?

  • IDL, LDL, and VLDL
  • LDL, HDL, and VLDL (correct)
  • Chylomicrons, LDL, and HDL
  • Chylomicrons, IDL, and VLDL

Which classification of hyperlipoproteinemia is considered rare according to Fredrickson-LevyLees Classification?

  • Type IIa (LDL)
  • Type IIb (LDL + VLDL)
  • Type I (chylomicrons) (correct)
  • Type IV (VLDL)

What is the primary defect in familial hypercholesterolemia?

  • Inability to bind LDL to the LDL receptor (correct)
  • Overproduction of cholesterol
  • Deficiency of HDL cholesterol
  • Inability to bind VLDL to the receptor

Which lipoprotein class is most common in Type IIb hyperlipoproteinemia?

<p>LDL (A)</p> Signup and view all the answers

What is the primary characteristic of plasma lipoproteins?

<p>Spherical particles with phospholipid surfaces (A)</p> Signup and view all the answers

Which lipoprotein class is associated with a predisposition to coronary, cerebrovascular, and peripheral vascular arterial disease?

<p>LDL (D)</p> Signup and view all the answers

Which of the following is used to identify groups of patients qualifying for treatment with statins?

<p>Total cholesterol and statin benefit groups (D)</p> Signup and view all the answers

At what age should the ten-year risk for ASCVD be calculated in patients without ASCVD or LDL-C ≥ 190 mg/dL?

<p>40 (B)</p> Signup and view all the answers

For which group of patients can lifetime risk calculation be done?

<p>Patients age 20–39 with 10-year risk &lt; 7.5% (C)</p> Signup and view all the answers

Which component is NOT included in the estimator for calculating risk?

<p>Triglycerides (A)</p> Signup and view all the answers

What is a primary purpose of the 2018 ACC/AHA Blood Cholesterol Guideline regarding statin therapy?

<p>To reduce the 10-year risk of ASCVD in secondary intervention (C)</p> Signup and view all the answers

What is the primary consequence of a lack of LDL degradation by cells?

<p>Unregulated biosynthesis of cholesterol (B)</p> Signup and view all the answers

Which condition is associated with hypertriglyceridemia?

<p>Obesity (C)</p> Signup and view all the answers

What is a secondary cause of hypocholesterolemia?

<p>Malnutrition (B)</p> Signup and view all the answers

Which drug class is associated with causing hypercholesterolemia?

<p>Mirtazapine (D)</p> Signup and view all the answers

What condition can lead to low HDL levels?

<p>Myeloproliferative diseases (C)</p> Signup and view all the answers

Which disease is NOT associated with an increase in triglyceride levels?

<p>AIDS (A)</p> Signup and view all the answers

What symptoms might symptomatic patients with dyslipidemia complain of?

<p>Chest pain and palpitations (B)</p> Signup and view all the answers

Which of the following signs may indicate dyslipidemia in a patient?

<p>High BMI and high waist size (C)</p> Signup and view all the answers

Which of the following laboratory test results are commonly elevated in dyslipidemia?

<p>Elevations in total cholesterol, LDL, triglycerides (B)</p> Signup and view all the answers

How often should adults 20 years of age or older have a fasting lipoprotein profile measurement according to the text?

<p>Once every 5 years (A)</p> Signup and view all the answers

Which equation can be used for calculating VLDL levels based on triglyceride values?

<p>$VLDL = triglyceride/5$ (C)</p> Signup and view all the answers

What should be done if a nonfasted lipoprotein profile shows a total cholesterol ≥200 mg/dL or HDL-C <40 mg/dL?

<p>Order a fasting lipoprotein profile for follow-up (A)</p> Signup and view all the answers

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