Anatomy - MSK MCQ (MD2)

Which of the following statements regarding the notochord's role in vertebral development is NOT correct?

During which stage of vertebral development do the paired primary centres of chondrification first form, and what do they differentiate into?

A neonate presents with scoliosis. Imaging reveals hemivertebrae. Which developmental error most likely caused this condition?

A mutation in Hox10 expression results in which of the following skeletal abnormalities?

In the vertebral development process, failure of segmentation during which stage is most likely to result in block vertebrae?

During the mesenchymatous stage, sclerotome cells migrate to form which of the following vertebral structures?

The presence of interlaminar and neurocentral cartilage growth plates is characteristic of which stage of vertebral column development?

Which vertebral element contributes to the formation of the zygapophyseal joints and mammillary processes?

A 12-year-old patient has vertebral anomalies due to a lack of bone deposition at the site of the nucleus pulposus. What is the most likely congenital condition?

Which process drives the re-segmentation of somites during vertebral development?

Which of the following accurately describes the mesenchymatous stage of vertebral development?

Which vertebral anomaly arises due to a failure of one cartilage centre to develop during the cartilaginous stage?

The intervertebral discs align with which developmental structure during the cartilaginous stage?

During vertebral segmentation, what defines the location of a vertebral segment?

A patient is diagnosed with butterfly vertebra. What developmental abnormality most likely caused this condition?

Which vertebral structures form directly from the costal element during development?

How does the notochord contribute to vertebral development during the cartilaginous stage?

Which of the following is a direct consequence of Hox10 gene deletion in vertebral development?

Which of the following statements regarding the notochord’s role in vertebral development is NOT correct?

What is the significance of neurocentral cartilage growth plates in vertebral development?

In the osseous stage, which process contributes to the continuation of vertebral growth beyond birth?

What is the primary clinical manifestation of block vertebra?

What distinguishes the neural arch element in vertebral development?

What distinguishes the mesenchymatous stage from the cartilaginous stage in vertebral development?

During the osseous stage, which process is responsible for continuing vertebral growth after birth?

Which Hox gene expression error is associated with lumbar-isation of thoracic vertebrae?

What developmental process ensures nerve roots exit between vertebrae?

Failure of segmentation during which stage contributes to block vertebra?

Which vertebral structure forms exclusively from the costal element?

What clinical condition may result from the persistence of neurocentral cartilage after 8 years of age?

A neonate presents with thoracic ribs extending into the lumbar region. Which developmental process is most likely disrupted?

What is the role of the nucleus pulposus in intervertebral disc function?

Which of the following secondary ossification centres is responsible for increasing vertebral height during puberty?

Which condition results from excess nucleus pulposus formation during development?

What distinguishes vertebral growth plates from epiphyseal plates in long bones?