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This document appears to be a set of questions on pathophysiology, covering endocrine and neurological topics. Questions include topics on various conditions and their components including treatment and diagnosis.

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40 items ENDOCRINE CONDITIONS 1. Study the characteristics of hormones and the functions of hormones as chemical messengers a. Need to know 4 important things b. ch40 2. Study the factors affecting response of a target cell to a hormone a. Apply this clinically b....

40 items ENDOCRINE CONDITIONS 1. Study the characteristics of hormones and the functions of hormones as chemical messengers a. Need to know 4 important things b. ch40 2. Study the factors affecting response of a target cell to a hormone a. Apply this clinically b. Specifically how this can manifest as a pt with hormone deficiency c. Know 3 things d. Ch40 3. Study the mechanisms of hormone receptor interactions a. Specifically cell surface receptor sites b. Messenger mechanisms and hormone intracellular receptor complexes 4. Study the hypothalamic pituitary and organ pathways a. Read up on fig 40-3 5. Study the feedback mechanisms a. Think of specific examples for these diff pathways and apply clinically b. Read up on: Thyroid hormones, follicle stimulating hormone and ovum development 6. Study the types of diabetes melitus a. Pathogenesis of each 7. Study the different diagnostic tests for diabetes melitus a. Significance of those tests (each) 8. Study the clinical manifestations of diabetes melitus a. what are the 3Ps b. Seizures and coma 9. Study the microvascular and macrovascular complications of diabetes melitus a. How to educate pts regarding future consequences from these complications 10. Study the laboratory criteria for diabetes melitus a. Look up chart 41-4 11. Study cushing syndrome a. causes b. Manifestations c. Management 12. Study the categories of endocrine disorders a. Think of specific examples for each category 13. Study gigantism versus acromegaly a. Causes b. Manifestations 14. Study hyperthyroidism, graves disease and thyroid storm a. Causes b. Manifestations c. Management 15. Study adrenal gland a. Parts b. Zones c. Different hormones produced by the parts and zones NEUROLOGICAL CONDITIONS 16. Study neurons and action potential a. Synaptic transmission b. Messenger molecules c. Excitatory and inhibitory postsynaptic potentials d. Neurotransmitters: i. amino acids- gaba ii. Neuropeptides- endorphins and enkephalins iii. Monoamines- serotonin, dopamine, norepinephrine and epinephrine 17. Study and differentiate: a. post herpetic neuralgia b. migraine headache c. complex regional pain syndrome d. trigeminal neuralgia e. www.ninds.nih.gov/health-information/disorders/complex-regional-pain-syndrome #:~:text=Complex%20regional%20pain%20syndrome%20 18. Study deep pain in children a. How to assess and manage pain in children 19. Study myasthenia gravis a. Etiology b. Pathogenesis c. Clinical manifestations d. Diagnosis e. Treatment f. Look at fig 15-7 20. Study and differentiate: a. multiple sclerosis b. Guillain-Barre syndrome c. Myasthenia gravis d. Cerebellar damage 21. Study parkinson's disease a. Etiology b. Pathogenesis c. Clinical manifestations d. Tx e. Look up table 15-1 and fig 15-12 22. Study amyotrophic lateral sclerosis ALS- new gehrig's disease a. Etiology b. Pathogenesis c. Clinical manifestation d. tx 23. Study multiple sclerosis a. Etiology b. Pathogenesis c. Clinical manifestations d. Course e. Diagnosis f. Treatment 24. Study and differentiate: a. Central cord syndrome b. brown sequard syndrome c. Anterior cord syndrome d. Conus medullaris syndrome e. Autonomic dysreflexia 25. Study coup versus contrecoup injury 26. Study cerebral edema a. differentiate i. Vasogenic edema ii. cytotoxic edema 27. Study and differentiate: a. Epidural hematoma b. Subdural hematoma c. Intraparenchymal hematoma d. Intraventricular hematoma 28. Study intraocular pressure and glaucoma a. Control of intraocular pressure b. Primary open angle glaucoma c. Angle closure glaucoma d. Include: i. Etiology ii. Manifestations iii. Diagnosis iv. Tx 29. Study and differentiate: a. Acute otitis media b. Acute Vestibular neuronitis c. Benign paroxysmal positional vertigo BPPV d. Study Meniere's disease e. Vestibular Neuronitis - StatPearls - NCBI Bookshelf (nih.gov) 30. Study everything about diabetic retinopathy 31. Study a. anterior basilar skull fracture b. Cerebrospinal fluid leak c. How to assess for the presence of CSF leak 32. Study the different combinations of increased or decreased: a. thyroid stimulating hormone (THS) b. serum p3 c. Serum p4 d. their clinical significances (what disease conditions would be seen if u have changes in the three diff hormones) 33. Study hyperthyroidism and its manifestations 34. Study hyperthyroidism and its diagnostic laboratory and imaging tests 35. Study hyperthyroidism a. its pharmacologic medical care and b. non pharmacological nursing care 36. Study type 2 diabetes mellitus and its laboratory tests a. Significance of each test 37. Study the microvascular and macrovascular complications of type 2 diabetes mellitus a. How to prevent or minimize these from occurring or worsening (prevention) 38. Study the manifestations of increased intracranial pressure 39. Study: a. different levels of consciousness b. Glasgow coma score c. Corticate and cerebrate posturing d. Oculocephalic reflex e. Vestibulo ocular reflex f. Corneal reflex g. Pupillary response types h. Gag reflex i. Babinski reflex j. Crass night reflex? k. Cronus reflex l. Hoffman reflex m. Cushing type n. If the reflex is abnormal, something is wrong with the pt. What is the part of the nervous system that could be diseased? Some of these are focusing on the brain and some on the lower parts like spinal cord (upper and lower motor neuron lesions) 40. Study glaucoma a. Etiology b. Types c. Diagnosis d. Tx e. complications

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