HUBS1416 Neurotransmitters & Receptors PDF

HUBS1416 Learning objectives Neurotransmitters & Receptors AND Integration of Electrical Signals  Give the major roles of each neurotransmitter mentioned in the lecture and briefly explain their involvement in disease  Briefly explain the ways in which neurotransmitters and/or their int...

HUBS1416 Learning objectives Neurotransmitters & Receptors AND Integration of Electrical Signals  Give the major roles of each neurotransmitter mentioned in the lecture and briefly explain their involvement in disease  Briefly explain the ways in which neurotransmitters and/or their interaction with their receptors can be manipulated for therapeutic effects  Describe the ways in which the removal of neurotransmitters from the synaptic cleft can be manipulated with drugs  Identify the ways in which analgesia can be achieved  Identify the main neurotransmitter for each division of the autonomic nervous system & use your knowledge of the parasympathetic and sympathetic functions to determine the effects these neurotransmitters provide  List the major adrenergic and cholinergic receptor subtypes  Know the main functions (those identified in the lecture) that each receptor sub-type for noradrenaline and acetylcholine are responsible for  Use your knowledge of the noradrenaline and acetylcholine receptor subtypes to predict the effect of activating or blocking these receptors & what effect would be seen with excess or inadequate amounts of neurotransmitter  Explain the concepts of inhibitory and excitatory signals & neurotransmitters and compare this to an inhibitory and excitatory neurons  Explain the ways in which neurons can interact with each other to achieve coordinated & complex control of the various body systems  Describe the components of a reflex arc using the provided examples  Describe the purpose and mechanism of the provided example reflexes  Explain how reflex testing can be used diagnostically  Explain, in simple terms, how/why a simple reflex response can provide information about the functioning of both peripheral and central neurons  Explain why some reflexes are present in infancy and disappear as we mature, while some reflexes are absent in infancy, and appear as we mature  Use your knowledge from this topic to explain the underlying pathophysiology in relevant clinical situations & possible effective therapeutic interventions