Pediatric and Geriatric Considerations PDF

Summary

This document discusses pediatric and geriatric immunity. Pediatric immunity benefits from maternal antibodies initially, while geriatric immunity shows decreased T-cell activity and antibody response.

Full Transcript

Pediatric and Geriatric Considerations Pediatric Immunity Sufficient IgM but deficient IgG & IgA responses Maternal antibodies provide protection within the fetal circulation and during the first months of life Geriatric Immunity Decreased T-cell activity (Thymus size is 15% of its maximum size) Th...

Pediatric and Geriatric Considerations Pediatric Immunity Sufficient IgM but deficient IgG & IgA responses Maternal antibodies provide protection within the fetal circulation and during the first months of life Geriatric Immunity Decreased T-cell activity (Thymus size is 15% of its maximum size) Thymic hormone production drops, as does the organ’s ability to mediate T-cell differentiation Decreased antibody response to antigens

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