Biopharmaceutics And Pharmacokinetics (VIOLET PACOP) PDF

Biopharmaceutics and Pharmacokinetics (VIOLET PACOP) 1. It is the ability of a drug to exist in two or more crystalline form: A. Chirality B. Polymorphism C. Stereoisomerism D. A and C E. None of these 2. Arrange the following dosage for...

Biopharmaceutics and Pharmacokinetics (VIOLET PACOP) 1. It is the ability of a drug to exist in two or more crystalline form: A. Chirality B. Polymorphism C. Stereoisomerism D. A and C E. None of these 2. Arrange the following dosage forms from highest to lowest dissolution rate: I. Solution III. Suspension II. Capsule IV. Tablet A. I, II, III, IV B. I, III, II, IV C. IV, III, II, I D. IV, II, III, I E. None of these 3. All of the following statements aretrye regarding particle size of a drug, EXCEPT: A. Reducing the particle size can decrease the surface are the molecule exposed to the solvent. B. Reduction of paticle size can be achieved by micronisation using jet mill, spray drying and air attrition methods. C. The dissolution of some drugs available in the market has been improved by reducing the particle size. D. Reducing the particle size of a drug may increase drug absorption. E. None of these 4. Which of the following may increase drug dissolution rate? I. Too muh binder II. Insoluble diluents III. High amount of lubricants A. I only B. I and II C. II and III D. I, II, AND III E. None of these 5. Which of the following is not true regarding the purpose of tablet coating? A. Improves palatability B. Improve aesthetic value of tablet C. Improve stability D. Improve in-vivo degradation E. None of these 6. A surface active agent that facilitates the absorption of lipophilic drug or water insoluble drugs A. Bile B. Albumin C. Renin D. Gastric acid E. None of these 7. Phase 2 metabolism that protects the body against chemically reactive metabolites A. Sulfate conjugation B. Glutathione conjugation C. Methylation D. Acetylation E. Glycine conjugation 8. All of the following listed below are processes of drug excretion, EXCEPT: A. Glomerular filtration B. Active secretion C. Tubular secretion D. Tubular reabsorption E. None of these 9. It is the basic functional unit of the kidney A. Glomerulus B. Loop of henle C. Nephron D. Collecting tubule  E. None of these 10. Creatinine clearance of a patient with kidney failure A. 60-89 mL B. 30-59 mL C. 15-29 mL D.