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San Lorenzo Ruiz College of Ormoc, Inc.

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pharmacology drug action medicine biology

Summary

This document contains multiple-choice questions about pharmacology. The questions cover topics such as drug action on voltage-gated ion channels, tubulin binding, and targeting of specific proteins in the heart. The questions also delve into the science of pharmacodynamics.

Full Transcript

Voltage-gated ion channels serve as site of actions for drugs such as I. Diltiazem and Nifedipine II.Lidocaine and Procaine III.Captopril and Losartan a.I only b.I and II c.III only d.I and III e.I, II, and III Drugs with mechanism of action that involves Tubulin-binding leading to l...

Voltage-gated ion channels serve as site of actions for drugs such as I. Diltiazem and Nifedipine II.Lidocaine and Procaine III.Captopril and Losartan a.I only b.I and II c.III only d.I and III e.I, II, and III Drugs with mechanism of action that involves Tubulin-binding leading to loss of function of the structural protien include a.Cyclosporine b.Neostigmine c.Colchicine d.Glibenclamide e.Metformin What type of protien is primarily targeted by Digitalis glycosides when they exert their effect on the heart? a.Receptors b.Ion channels c.Enzymes d.Transporters e.Structural protiens Cyclic Adenosine Monophophate (cAMP) is generated as a secondary messenger by the action of the enzyme Adenylyl Cyclase. The substrate for the synthesis of cAMP is a.AMD b.ADP c.ATP d.GTP e.Adenosine Which of the following features cahracterize nicotinic, GABA-A, and Glutamate receptors? a.They control the movements of ions and out of the cell b.Their action is mediated by secondary messengers c.They all have excitatory effect on the cell membrane d.They are located on the cytoplasm Stimulation of Beta-adrenoceptor, a G- protien-linked receptor involves a generation of a secondary messenger known as a.IP3 b.cGTP c.DAG d.cAMP e.Calcium ions Pharmacodynamics Pharma acodynamics is A.. T A The science ence that examines the interrelationship he scie ationshiip of interrela of the physicochemical physsicocchemical properties properties of of the the drug druug and and the e route of administration on the rate and extent of systemic systemiic circulation circulation n B. The sscience cience of of the kinetics kin netics of drug drug absorption, abso orption, distribution distribu n and ution and elimination elimiination n The C. Th part he pa pharmacology, rmacologyy, which deals art of phar deals with h what what a drug rug does dr oes to the body do D. The scscience, cience, which dealss with tthe physicochemical he physicoochemical properties prroperties of of the drug that thaat allow it to o be be designed desig gned dosage into d forms osage form ms and E. A and B Lanoxin acts on which of the following. A.Na/K ATPase pump B.Na/H ATPase pump C.H/K ATPase pump D.Na/Ca ATPase pump E.None of the above

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