White Blood Cell Disorders PDF

411 Oral Medicine, Diagnosis & Periodontology I Note : students are responsible for any material given in the lectures and sections even if not mentioned in the handouts Textbook: Burkets Oral Medicine 12th edition  White blood...

411 Oral Medicine, Diagnosis & Periodontology I Note : students are responsible for any material given in the lectures and sections even if not mentioned in the handouts Textbook: Burkets Oral Medicine 12th edition  White blood cell disorders Dr. Amira Abdelwhab Lecturer od Oral Medicine, Diagnosis and Periodontology  Neutrophils 70% Granular cells Eosinophils White blood cells Basophils Lymphocytes (B &T) Non granular Monocytes Quantitative disorders Qualitative disorders Agranulocytosis Multiple Myeloma Cyclic neutropenia Leukemia Infectious mononucleosis Agranulocytosis No neutrophils are found in peripheral circulation Etiology 1- Idiopathic 2- Secondary to drugs, irradiation……  Neutrophils Granular cells Eosinophils Basophils  Neutrophils Granular cells Eosinophils Basophils  Clinical features Age : adults Gender: F>>M High fever, chills, fatigue and sore throat Infection is a characteristic feature affecting mouth, GIT, GUT, RT and skin  Oral features 1. Oral ulcerations particularly gingiva and palate. The ulcers are Large Deep Irregular Necrotic Painful No inflammatory halo at margins Covered by pseudomembrane 2. Secondary fusospirochetal infection 3. Regional lymphadenopathy  Lab. findings CBC: Absence of granulocytes Total WBCs