Mpox: Risk, Management and Vaccination PDF

Med22 ! https://youtu.be/ev919yS8sv0?si=jT5KvBxtLi72eNgX ‫ﺣﻠﻮ و ﺗﻘﺮﯾﺒﺎ ﺷﺎﻣﻞ‬ We will study the monkeypox lecture " instead of the COVID lectures due to it being a new topic and because it has caused a recent outbreak. ...

Med22 ! https://youtu.be/ev919yS8sv0?si=jT5KvBxtLi72eNgX ‫ﺣﻠﻮ و ﺗﻘﺮﯾﺒﺎ ﺷﺎﻣﻞ‬ We will study the monkeypox lecture " instead of the COVID lectures due to it being a new topic and because it has caused a recent outbreak.  mm Means classes or subclasses of the virus itself G As smallpox from the same group recent ‫اﻟﻲ ﻋﻤﻠﺖ ﻟﻨﺎ‬ outbreak They are important because they describe the behavior of the disease.  ‫) ‪It’s a zoonotic disease ( from animal to human‬‬ ‫اﻟﺤﯿﻮاﻧﺎت اﻟﻲ ﯾﺴﻮو ﻋﻠﯿﮭﺎ ﺗﺠﺎرب ﻣﻨﮭﺎ اﻟﻘﺮود‬ ‫ﻓﺎﻛﺘﺸﻔﻮا ﻓﻲ ﺑﻌﻀﮭﻢ ذا اﻟﻔﯿﺮوس و طﻠﻌﻠﻨﺎ ﻓﻲ اﻟﺨﻤﺴﯿﻨﺎت‬ ‫ﻟﻤﺎ اﻧﺘﮭﺖ ﻓﺘﺮة اﻟﺘﻄﻌﯿﻢ و اﻧﺘﮭﻰ اﻧﺘﺸﺎر ‪small pox‬‬ ‫‪ virus‬ﻟﻘﻮا ان ﺣﺎﻻت ‪ mpox‬ﺑﺘﺰداد‬ ‫ﻻن ‪small pox vaccine suppress and limit‬‬ ‫‪the infectivity of Mpox virus‬‬ ‫اول ﻛﺎن ‪ behavior‬ﺣﻘﻮ و اﻧﺘﺸﺎره ﻣﺨﺘﻠﻒ اول ﻛﺎن‬ ‫ﻋﻦ طﺮﯾﻖ ‪ animals‬اﻻن اﺻﺒﺢ ﺣﺘﻰ ‪Sexually‬‬ ‫‪ transmitted‬او ﻋﻦ طﺮﯾﻖ اﻟﻤﻼﻣﺴﺔ‬  started zoonotic Transmission: as then contact and even STD Mpox spreads through close contact with an infected person or animal, or with material contaminated with the virus. Human-to-human transmission occurs through: main Direct contact with infectious skin or mucocutaneous lesions G* Respiratory droplets during prolonged face-to-face contact * Fomites (e.g., contaminated clothing or linens) & Animal-to-human transmission can happen through: Bites or scratches from infected animals Preparation or consumption of bushmeat  pastule or crust ‫ھﻮا ﯾﺴﻮي ﻓﻲ اﻟﺠﻠﺪ‬ ‫ف ﻋﻦ طﺮﯾﻖ اﻟﻤﻼﻣﺴﺔ ﯾﻨﺘﺸﺮ ﻣﻦ ﺷﺨﺺ‬ ‫ﻟﺸﺨﺺ‬ ‫ﺗﺤﺖ ﺣﻨﺸﻮف‬ ‫ ﻣﻮﺟﻮد ﻟﻼن ﯾﻌﻨﻲ ﯾﻤﻜﻦ اي ﺷﺨﺺ ﯾﺼﺎب ﺑﯿﮫ ﻣﻦ‬zoonotic ‫اﻻﻧﺘﻘﺎل‬ animal that is infected then they handle animals ‫زي ﻟﻤﺎ ﯾﺠﺮح اﻟﺸﺨﺺ ﻧﻔﺴﮫ‬ But MAINLY NOWDAYS is through human to human direct contact ( important ) ‫ﺗﺤﺐ ﺗﺴﺄل ﻋﻠﯿﮫ‬  manto human 2 ws.es It only illustrates the evolution of the virus and the mode of transmission Threw Human immunodeficiency virus -1 group M Rabies is only present a in animals so its transmission Ebola used to be zoonotic It strictly became human to human only is from animal to human not but it passed in these stages from human to human. till it became from human to human  C distinct ddx pito chicken measles Picture of any virus illnes  sinceitbecame sexually ‫ﻣﺎ ﯾﻜﻮن ﻣﻌﺪي ﻟﻤﺎ ﺗﻜﻮن ﻓﻲ‬ thepapules transmitted ‫ذي اﻟﻤﺮﺣﻠﺔ‬ couldbeinvaginaanus is couldbemistakenfor STDhopesetc other it involves Edina  Swab from pus in the pustule and if there isn’t any pus we could do debriment from anus Gold standard for diagnosis  Live attenuated vaccine mm We did modifications of the old smallpox vaccine It is usually 2 doses and only for high risk people Important And we gave it as pre exposure prophylaxis 1st dose It must be within 4 days of exposure + then after 14 days we give the other dose ‫ ﺷﺎﻛﻚ اﻧﮫ‬exposed Still zoonotic but it’s mostly transmitted through human to human direct contact & sexually even If I want to declare any disease as public health emergency ? I must have the answers for these questions They found out that the mortality from the strain that is mainly transmitted human to human is more significant than the zoonotic u one ‫ﻧﺤﻦ ﻋﺎرﻓﯿﻨﮫ ﻣﻦ اﻟﺨﻤﺴﯿﻨﺎت‬ YES, if it reaches multiple Countries, it’s is significant A lot of Mpox cases could be underreported because they don’t diagnose it due to the lack of PCR as a diagnostic tool in many countries This picture shows where is each clade is more endemic ‫ ﻣﻨﺘﺸﺮة اﻛﺜﺮ ﻓﯿﻦ ﺑﺲ ﻧﻌﺮف‬clade ‫ﻣﺎ ﯾﮭﻤﻨﺎ ﻧﻌﺮف اي‬ Why it is more prevalent in a particular country? The theory behind it to develop health programs How the transmission occurs? ‫ اﻋﺘﻘﺪ ﺧﻼص ﻋﺮﻓﺘﻮ ﻛﯿﻒ اﻟﺴﺆال ﺣﯿﺠﻲ‬:! ‫اﻟﺪﻛﺘﻮرة‬ Who the high risk individuals are (ex: farmers in human to human through ) ‫ﻋﺪﺗﮫ ﻟﻜﻢ ﻛﻢ ﻣﺮه‬ Africa or transmission through sexual contact in (direct contact Europe It’s not only a pustule that comes and goes It is sth more concerning The doctor didn’t go through the rest of the slides, and I believe they’re just a review of what was already discussed earlier. You might want to take a look at them, they summarize everything