Tutorial 4 - Proteins & Amino Acids PDF

Summary

This tutorial covers proteins and amino acids, including their structure, properties, and metabolism. It presents practice questions on topics such as dietary protein digestion, disease, and metabolic functions.

Full Transcript

TUTORIAL 4 (PROTEINS & AMINO ACIDS) Semester 1, 2024/2025 DR. MARIATI BT ABDUL RAHMAN Department of Craniofacial Diagnostics and Biosciences, Faculty of Dentistry, UKM 1. Describe 4 organizational levels of the structure of protein...

TUTORIAL 4 (PROTEINS & AMINO ACIDS) Semester 1, 2024/2025 DR. MARIATI BT ABDUL RAHMAN Department of Craniofacial Diagnostics and Biosciences, Faculty of Dentistry, UKM 1. Describe 4 organizational levels of the structure of proteins. 2. Describe the differences between myoglobin and haemoglobin. 3. What are the classes of antibodies? 4. A patient complains about the bleeding of his gum whenever he brushes his teeth. He mentioned that he is on a high protein diet in the last 6 months and hates fruits and vegetables. What is the cause of his bleeding gums? A. He is using a toothbrush with hard bristles. B. He suffers from scurvy. C. His flossing techniques is wrong. D. He suffers from osteogenesis imperfecta. 5. Classify amino acids in terms of its properties, its synthesis in the body and its metabolic fate. Explain each terminology with examples. 6. Briefly describe how 10 non essential amino acids are synthesized in our body. 7. Describe the process of dietary protein digestion and absorption. 8. Describe the concept of amino acid pool and protein turnover. 9. Explain the meaning of transamination, oxidative deamination & decarboxylation with examples. 10.Explain the metabolism of ammonia using a diagram. 1 11.List out the sources of ammonia in the body and explain how ammonia is transported. 12.Explain how ammonia effects the brain. 13.Explain what are the causes of hyperammonaemia. 14.Explain the urea cycle and how it is regulated. 15.Differentiate the difference between purely glucogenic, purely ketogenic and both ketogenic and glucogenic amino acids. 16.Explain the causes of these diseases: Phenylketonuria, alkaptonuria, tyrosinemia & maple syrup urine diseases. 17.Explain the inter-organ exchange of amino acids during fed and fasting state. 18.Explain what is nitrogen balance, and give examples of positive and negative nitrogen balance. 1. 2. 3. 4. 5. 6.. 7. 2

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