Treatment of Cough PDF
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Summary
This document provides an overview of different treatments for coughs, including antitussives, expectorants, and mucolytics. It also covers the mechanisms of action and common uses of these medications. The information is presented in a detailed manner suitable for a medical or pharmaceutical context.
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1) Antitussives (cough centre suppressants) Drugs suppress cough & produces symptomatic relief MOA Mainly suppress cough center in medulla (both central & peripheral effects) E.g., Opoid drugs (codeine, pholcodeine, noscapine, dextromethorphan) Opioid = most effective for cough i...
1) Antitussives (cough centre suppressants) Drugs suppress cough & produces symptomatic relief MOA Mainly suppress cough center in medulla (both central & peripheral effects) E.g., Opoid drugs (codeine, pholcodeine, noscapine, dextromethorphan) Opioid = most effective for cough i) Codeine Codeine= prodrug metabolized to morphine It is an alkaloid found in Opium poppy plant Has less addiction resp. centre depressant ↓ Has useful antitussive action at low doses (
