Topical Anesthetics Study Guide PDF

Summary

This document provides a detailed overview of various topical anesthetics, including Benzocaine, Lidocaine, and others. It covers key aspects such as drug properties, dosage, onset, duration, and related considerations, making it a valuable resource for pharmacology students and healthcare professionals reviewing topical anesthetics.

Full Transcript

Topical Anesthetic Benzocaine Ester-metabolized in blood * by enzyme plasma * Class C drug No close-absorbed in cardiovascular system max * Benzocaine FDA for Methemoglobinemia &...

Topical Anesthetic Benzocaine Ester-metabolized in blood * by enzyme plasma * Class C drug No close-absorbed in cardiovascular system max * Benzocaine FDA for Methemoglobinemia & Spray-Warning by Onset 30 sec - 2 min Duration 5-15 min Anbeso-given to babies Butacaine Sulfate * EMLAD Ointment Prilocaine Lidocaine Dose Sml of 4% solution : onset 1hr Duration 2-3 his Penetrate intact Skin DyDonine Hydrochloride Anesthetize skin prior to IV insertion * Ketone& 200mg max close Onset : Slow up to 10 minutes Oragix Duration : up to an hour & Class B A Max S cartridges Liquid of room temp get on tissue , Lidocaine 20 min average 14-31 min Amice Lidocaine / Prilocaine 2 SY.. AMIDES ! * Most common form thats & an ointment Use on abraded ulcerated tissues Water Soluble Tetracaine Hydrochloride Ester 2% topical preparation * Most potent topical Slow onset 20 min - High risk of toxicity Duration 45 min = Rapidly absorbed in tissue Cetacaine 20 my max close * Topicals more concentrated be they have to diffuse penetrate tissues& * * Unmetered benzocaine spray = Too much (methemoglobinemia) & first 2-3mm Blocking nerve conduction * Concentrations of topicals are higher than those used for injection * Prilocaine biotransformed where ? Lungs + Liver * Lidocaine biotransformed where ? Liver & * Excretion & takes place where? Kidneys * Absolute contraindication of Oraquix? Previous reaction to amide anesthetics

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