Thyroid Drugs Part 1.docx

Thyroid Drugs \#\#\# \*\*Slide 1: Overview of Thyroid Hormones\*\* 1\. \*\*Which of the following thyroid hormones is more biologically active but less abundant in the bloodstream?\*\* \- A. T4 \- B. T3 \- C. Reverse T3 (rT3) \- D. Thyroglobulin \*\*Answer:\*\* B. T3【137†source】 2\. \*\*Wh...

Thyroid Drugs \#\#\# \*\*Slide 1: Overview of Thyroid Hormones\*\* 1\. \*\*Which of the following thyroid hormones is more biologically active but less abundant in the bloodstream?\*\* \- A. T4 \- B. T3 \- C. Reverse T3 (rT3) \- D. Thyroglobulin \*\*Answer:\*\* B. T3【137†source】 2\. \*\*What percentage of T4 is converted to T3 in peripheral tissues?\*\* \- A. 10% \- B. 20% \- C. 50% \- D. 80% \*\*Answer:\*\* D. 80%【137†source】 3\. \*\*Which enzyme is required for the conversion of T4 to T3 in peripheral tissues?\*\* \- A. Thyroid peroxidase \- B. Deiodinase \- C. Lipase \- D. Amylase \*\*Answer:\*\* B. Deiodinase【137†source】 \-\-- \#\#\# \*\*Slide 2: Thyroid Hormone Synthesis\*\* 1\. \*\*Thyroid hormone production begins with the uptake of which substance by the thyroid gland?\*\* \- A. Iodide \- B. Sodium \- C. Calcium \- D. Glucose \*\*Answer:\*\* A. Iodide【137†source】 2\. \*\*Which enzyme in the thyroid gland is responsible for converting iodide to iodine and facilitating hormone production?\*\* \- A. Deiodinase \- B. Thyroid peroxidase (TPO) \- C. Glutathione peroxidase \- D. Monoamine oxidase \*\*Answer:\*\* B. Thyroid peroxidase (TPO)【137†source】 3\. \*\*What thyroid hormone is formed by the combination of two diiodotyrosine (DIT) molecules?\*\* \- A. T3 \- B. T4 \- C. Reverse T3 \- D. Thyroglobulin \*\*Answer:\*\* B. T4【137†source】 \-\-- \#\#\# \*\*Slide 3: Thyroid Hormone Metabolism\*\* 1\. \*\*Most physiologically active thyroid hormone is derived from which hormone in the peripheral tissues?\*\* \- A. T4 \- B. T3 \- C. Reverse T3 \- D. TSH \*\*Answer:\*\* A. T4【137†source】 2\. \*\*Which of the following factors can affect thyroid hormone-binding proteins, reducing the availability of free T4 and T3?\*\* \- A. High stress \- B. Low calcium intake \- C. Decreased liver enzymes \- D. High sodium intake \*\*Answer:\*\* A. High stress【137†source】 3\. \*\*What percentage of T4 is bound to thyroid-binding globulin (TBG)?\*\* \- A. 30% \- B. 50% \- C. 70% \- D. 90% \*\*Answer:\*\* C. 70%【137†source】 \-\-- \#\#\# \*\*Slide 4: Hypothyroidism - Causes and Symptoms\*\* 1\. \*\*Which autoimmune disorder is a common cause of hypothyroidism?\*\* \- A. Graves\' disease \- B. Hashimoto\'s thyroiditis \- C. Addison\'s disease \- D. Cushing\'s syndrome \*\*Answer:\*\* B. Hashimoto\'s thyroiditis【137†source】 2\. \*\*Which of the following symptoms is commonly associated with hypothyroidism?\*\* \- A. Weight loss \- B. Heat intolerance \- C. Constipation \- D. Tachycardia \*\*Answer:\*\* C. Constipation【137†source】 3\. \*\*What is the most common cause of hypothyroidism worldwide?\*\* \- A. Iodine deficiency \- B. Radiation therapy \- C. Pituitary tumor \- D. Viral infection \*\*Answer:\*\* A. Iodine deficiency【137†source】 \-\-- \#\#\# \*\*Slide 5: Thyroid Function Tests\*\* 1\. \*\*Which of the following thyroid function tests is used as the primary screening tool for thyroid disorders?\*\* \- A. Free T4 \- B. TSH \- C. Free T3 \- D. Thyroglobulin antibodies \*\*Answer:\*\* B. TSH【137†source】 2\. \*\*In patients with primary hypothyroidism, what would you expect the TSH levels to be?\*\* \- A. Low \- B. Normal \- C. High \- D. Suppressed \*\*Answer:\*\* C. High【137†source】 3\. \*\*Which of the following tests can help diagnose autoimmune thyroid disorders like Hashimoto's thyroiditis?\*\* \- A. TSH receptor antibodies \- B. Anti-thyroglobulin and thyroid peroxidase (TPO) antibodies \- C. Free T3 \- D. Reverse T3 \*\*Answer:\*\* B. Anti-thyroglobulin and thyroid peroxidase (TPO) antibodies【137†source】 \-\-- \#\#\# \*\*Slide 6: Thyroid Hormones - Intracellular Action\*\* 1\. \*\*Which inflammatory markers can impair intracellular T3 production?\*\* \- A. CRP and ESR \- B. Platelet count and hemoglobin \- C. White blood cells and neutrophils \- D. Calcium and potassium \*\*Answer:\*\* A. CRP and ESR【137†source】 2\. \*\*Which enzyme plays a major role in converting T4 to T3 within peripheral tissues?\*\* \- A. D2 (Type 2 deiodinase) \- B. TPO \- C. Amylase \- D. Alkaline phosphatase \*\*Answer:\*\* A. D2 (Type 2 deiodinase)【137†source】 3\. \*\*In states of illness or inflammation, the body preferentially converts T4 into which inactive thyroid hormone?\*\* \- A. T3 \- B. Reverse T3 (rT3) \- C. Thyroglobulin \- D. TSH \*\*Answer:\*\* B. Reverse T3 (rT3)【137†source】