Cell and Molecular Biology Study Guide PDF

### **Look at general Photos** ### **Chapter 13: Cytoskeleton** 1. - i. - - 2. - - - 3. - - 4. - - ### **Chapter 15: Extracellular Matrix (ECM)** 1. - i. ii. - 2. - iii. iv. - v. ### **Chapter 16: Cell Signaling** - 1. - -...

### **Look at general Photos** ### **Chapter 13: Cytoskeleton** 1. - i. - - 2. - - - 3. - - 4. - - ### **Chapter 15: Extracellular Matrix (ECM)** 1. - i. ii. - 2. - iii. iv. - v. ### **Chapter 16: Cell Signaling** - 1. - - i. ii. - 2. - iii. iv. v. 1. - vi. 3. - ### **Chapter 17: Cell Cycle** 1. - i. ii. 1. iii. iv. v. vi. vii. - viii. ix. 2. - x. xi. - xii. ### **Chapter 13: Cytoskeleton** 1. - - - 2. - - - 3. - - 4. - - ### **Chapter 15: ECM** 1. - - ### **Chapter 13: Cytoskeleton** 1. - i. ii. iii. - - 2. - - - 3. - - 4. - - - ### **Chapter 15: ECM** 1. - - - 2. - - - ### **Chapter 16: Cell Signaling** 1. - - - 2. - - - 3. - - ### **Chapter 17: Cell Cycle** 1. - - - 2. - - - 3. - - **Study Guide** --------------- ### **Chapter 13: Cytoskeleton (Sections 13.1--13.5)** #### **Key Concepts:** 1. - - - - - 2. - - - - - - - - 3. - - 4. - - - - - - ### **Chapter 15: Extracellular Matrix (ECM) (Section 15.2)** #### **Key Concepts:** 1. - - - - - - - - 2. - - - ### **Chapter 16: Cell Signaling (Sections 16.1--16.5)** #### **Key Concepts:** 1. - 2. - - 3. - - 4. - - 5. - ### **Chapter 17: Cell Cycle (Sections 17.1 and part of 17.2)** #### **Key Concepts:** 1. - - 2. - - - - - - 3. - - Know what the filaments are for G-actin, formin, Focal adhesions, integrins, stress fibers Cell cell junctions- adherens junctions and cadherins Considered one sarcomere- actin(thin) and myosin(thick) These things can slide past I band- region where they slide past each other M Line- anchor both sides together A band- entire filament where the regions are overlapping H zone - in the middle not overlapping Z disc- on the edge holding things together Myosin walks on actin and are ATP powered In the absence of Calcium there is no contraction or binding In the presence in the ER of muscle cells Ca binds to TNC and contracts Why are both calcium and ATP needed? Everytime one of the heads move they need atp to hold the tension in the muscle cell - - **Nerve impulse also increase nevere impulses** GTP and GDP Dyein(minus)and Kinesin(plus) for microtubules Motor proteins require atp Lamins and keratin Central Rod domain Intermediate filaments - - ECM- extracellular matrix Cell- matrix interaction Gly-x-Y- proline and hydroxyproline need vitamin C Scurvy Disaccharides Fiber necktin binds to adhesion proteins - Binding cells to the ecm and they bind to collagen etc Actin Integrin= focal adhesion IF-integrin= Hemidesmosome Signaling- Each monomer is one continues protein RAS FOXO- no signal =no happens no recruiting station without dimerization which makes it inactive Cell division- Restriction point in mammals START in yeast Know cyclin levels RB is a tumor suppressor and when it is phosphorylated it comes off and is regulated by CDK Signaling pathways- G- proteins- transmit the signal PIPS- are not proteins but are lipids found in the plasma membrane and recruited to the second green head group in slide 19 Inegrins can be a receptor for attaching to the ECM Capping proteins stabilize microfilaments