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Arellano University

Aira C. Gonzales, PTRP

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spinal cord injury neurology anatomy medicine

Summary

This document provides an overview of spinal cord injury, including its anatomy, blood supply, and various neuron types and tracts. It also discusses autonomic neurons and crucial complications related to spinal cord injuries.

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SPINAL CORD INJURY I.​ INTRODUCTION A.​Anatomy: Spinal cord ⭐ -​ Continuation of medulla oblongata ⭐ -​ Carry signal from brain to body -​ Start: Medulla oblongata (MO) -​ En...

SPINAL CORD INJURY I.​ INTRODUCTION A.​Anatomy: Spinal cord ⭐ -​ Continuation of medulla oblongata ⭐ -​ Carry signal from brain to body -​ Start: Medulla oblongata (MO) -​ End: ⭐ ⭐ -​ Adult: L1 (below) ⭐ -​ Child: L3 (above) -​ Lumbar puncture/tap: between L3-L4 (d/t: widest space) ⭐ -​ Conus Medullaris - Tapered end of SC ; Upper motor neuron lesion (UMN) -​ Cauda Equina - “horse tail” -​ Collection of lumbosacral nerve roots descending to exit -​ Lower motor neuron (LMN) -​ Filum Terminale - Piamater prolongation ⭐ -​ Attachment: 1st coccygeal vertebral BELL MAGENDIE LAW ⭐ V - Ventral E - Efferent M - Motor D - Dorsal A - Afferent S - Sensory Central ​ Butterfly shape ​ Gray matter (d/t unmyelinated axon) Peripheral ​ White matter (d/t myelinated axon) Rexed Laminae I - Marginal / Lissaur’s tract (Fxn.: Pain, touch, & temp.) II - Substantia Gelatinosa (Fxn.: Pain, touch, & temp.) III & IV - Nucleus Proprius (Fxn.:PKV- Proprioception, tactile discrimination, & vibration) V - Noxious stimulus from viscera VI - Noxious stimulus from skin / Mechanoreceptor VII - Clarke’s Dorsal Nucleus (Fxn.: Balance) VIII & IX - Ant. Horn Cell (Fxn.: Motor) X - Central gray Commissure Aira C. Gonzales, PTRP ⭐ B.​Blood Supply Vertical Arteries (Main blood supply) 1.​ Anterior Spinal Artery (ASA) a.​ Composed of 1 b.​ Ant ⅔ of SC c.​ MC Infarction 2.​ Posterior Spinal Artery (PSA) a.​ Composed of 2 b.​ Post ⅓ of SC Ant. Spinal A. Infarction > Post. Spinal A. Infarction ⭐Segmental Arteries AKA: Radicular Artery -​ For enhancement of blood supply A.​Great Ant. Radicular Artery (GARA) -​ AKA: Artery of Adamkiewicz -​ Loc: Left and anterior -​ Level supply: T6-L3 or T12 -L2 -​ Lower half of SC (Supply) B.​ Watershed Zone -​ T4-T6 (above adamkiewicz) -​ Fewer segmental Arteries -​ Decrease blood supply C. NEURONS 1.​ Sensory Neuron (Ascending neuron) -​ 1st order : Dorsal root ganglion -​ 2nd order : Interneuron (post horn ➡ thalamus) -​ 3rd order : Thalamus ➡ Sensory cortex 2.​ Motor Neuron (Descending neuron) -​ 1st order : UMN (Cortex ➡ ant. horn) -​ 2nd order : Interneuron -​ 3rd order : LMN (Ant. horn ➡ Spinal nerves) 3.​ Interneuron “Intermediary” -​ Most numerous -​ Connects motor to motor -​ Connects Sensory to sensory -​ Connects motor to sensory Aira C. Gonzales, PTRP 4.​ Autonomic Neurons -​ Carry neurons to: -​ Cardiac mm -​ Smooth mm -​ Visceral organs -​ *Involuntary mm* -​ Pre ganglionic -​ Brain / SC to ganglion -​ Post ganglionic -​ Ganglion to glands / organ D. TRACTS ⭐Lateral spinothalamic tract Ascending tracts 1.​ a.​ Fxn: Pain, Temp. 2.​ ⭐Ant spinothalamic a.​ Fxn: Touch, Pressure 3.​ ⭐Dorsal column a.​ Fxn: Proprio-kinesthesia-vibration (PKB) 4.​ Ant spinocerebellar & Post spinocerebellar a.​ Fxn: Balance 5.​ ⭐Spinotectal a.​ Fxn: Visual reflex 6.​ SpinoReticular a.​ Fxn: Wakefulness, “arousal” ⭐ Descending tracts 1.​ Lateral corticospinal tract a.​Fxn: Fine & skilled movement 2.​ ⭐Ant corticospinal a.​Fxn: Fine & skilled movement 3.​Tectospinal tract a.​Fxn: Visual reflex (efferent) 4.​Reticulospinal tract Aira C. Gonzales, PTRP 5.​ ⭐ a.​Fxn: UE/LE - stimulate / inhibit flexor & extensor Rubrospinal tract a.​Fxn: UE - flexion , LE - Extension 6.​ ⭐Vestibulospinal tract a.​Fxn: UE & LE - Extension b.​“Vextibulo” II. SPINAL CORD INJURY -​ Any insult to SC resulting to motor, sensory, and/or autonomic Fxn alteration A.​EPIDEMIOLOGY ​ Age: 16 - 30 y/o (average: 26y/o) ​ Sex: M>F ​ Time: July or during summer ​ Type: Tetraplegia (C5) > Paraplegia (T12) B.​ETIOLOGY -​ Traumatic 70% (more common) 1.​ MVA - MC cause ⭐ 2.​ Falls - MC among elders 3.​ Assaults/violence - GSW, Stabwounds 4.​ Sports - MC is diving -​ Non traumatic 1.​ Tumor or neoplasm 2.​ Toxins 3.​ infection 4.​ Congenital abnormalities -​ * SCIWORA* - “spinal cord injury without radiographic abnormalities” -​ Common: Pediatric pxs -​ Common cause: Improper handling falls C. CLINICAL SYNDROMES “Incomplete SCI” 1.​ Anterior cord syndromes ⭐ ⭐ -​ Worst prognosis -​ MOI: hyperflexion -​ S/sx: LE >UE -​ (-) Motor Fxn -​ (-) Pain & temp 2.​ Posterior cord syndromes Aira C. Gonzales, PTRP ⭐ ⭐ -​ Rarest ⭐ -​ MOI: hyperextension -​ S/sx: Abused joint “CHARCOT JOINT” -​ PKV: -​ (-) Proprioception -​ (-) Kinesthesia -​ (-) Vibration -​ Non traumatic cause a.​ Syphilis AKA: Tabes Dorsalis ⭐ -​ “sensory ataxia” -​ Cardinal signs: “RALI” -​ A. (+) Romberg sign -​ B. (+) Argyll robertson pupil -​ C. (+) Loss of reflexes -​ D. (+) Impaired sensation b.​ Subacute combined degeneration ⭐ ⭐ -​ Related to decrease or deficiency vit B12 (B12: produce myelin), also associated to “PERNICIOUS ANEMIA” (decrease B12) not direct will get SCI 3. Central Cord Syndromes ⭐ ⭐ -​ AKA: Walking SCI ⭐ -​ Most common incomplete SCI -​ Best prognosis ⭐ -​ MOI: Hyperextension or whiplash ⭐ (among drivers); ⭐ Cervical osteophyte (among Elders) -​ S/sx: UE > LE -​ (-) Motor Fxn -​ (-) Pain & temp. 4. Brown- Sequard cord -​ Half resection -​ MOI: Penetrating injuries, GSW, Stabwounds -​ S/sx: -​ Ipsi: (-) Motor, (-) PKV ⭐ -​ Contralateral: (-) Pain, (-) temp. Aira C. Gonzales, PTRP 5. Conus Medullaris Syndrome -​ UMNL -​ Spasticity -​ Hyperreflexive -​ Symmetrical 6. Cauda Equina Syndrome -​ LMNL -​ Flaccidity -​ Areflexive ⭐⭐⭐⭐ Conus Medullaris Cauda Equina Syndrome Paralysis Spastic Flaccid Bladder Spastic (reflexogenic Flaccid (areflexive bladder) bladder) Incontinence Urge incontinence Urinary retention Management 1.​ Pubic hair pulling 1.​ Crede maneuver 2.​ Abdominal stroking (pushing the abdomen 3.​ Suprapubic tapping inward & downward) 2.​ Valsalva maneuver Erection Reflexogenic Psychogenic “mental imagery” (common: S2-S4 lesions) Ejaculation (+) Needs more stimulation (+) D. CLINICAL MANIFESTATION -​ ⭐ 1.​ Spinal Shock Areflexia followed by SCI -​ Duration: 1 day to 3 days -​ (-) BULBOCAVERNOSUS REFLEX ⭐ -​ S: Pinch glands penis / clitoris or pull the Foley catheter -​ R: Anal sphincter contraction -​ ⭐ 2.​ Spasticity Probable to have: -​ Scoliosis -​ Hip dislocation Aira C. Gonzales, PTRP -​ Management: -​ Pharmacologic: -​ Baclofen -​ Dianzopen -​ Dantrolene sodium -​ Intrathecal injections -​ Peripheral nerve blocks -​ Surgery: Resection: -​ Myelotomy SC -​ Myotomy Muscle -​ Neurectomy Nerve -​ Rhizotomy Nerve root -​ Tenotomy Tendon 3.​ Autonomic dysreflexia ⭐ -​ MC occurred in T6 or above T6 (cut of parasympathetic activity) -​ Stimulus: bladder distention “noxious stimulus” - activate sympathetic -​ Response: release of parasympathetic activity -​ S/sx: -​ Increase BP -​ Decrease HR -​ Vasoconstrict (Below) -​ Vasodilation (Above) -​ 4ps -​ Pounding headache -​ Profuse sweating -​ Piloerection -​ “peys” face flushing -​ ⭐ -​ Management: Elevate head / “upright sitting” (standard mx) -​ Check bladder -​ Check other irritantants -​ Call the emergency 4.​ Orthostatic Hypotension (OH) -​ Stimulate: Elevate head -​ Response: decrease BP -​ Management: “”TAE CO” -​ Tilt table -​ Ankle pumps -​ Elevate legs -​ Compression stockings Aira C. Gonzales, PTRP 5.​ Respiratory Impairments -​ C4 above -​ Management: “MPG” -​ Mechanical ventilator -​ Phrenic nerve (C4-C5) stimulator ⭐ -​ Glossopharyngeal breathing -​ Assisted coughing: SUPINE ⭐ E. COMPLICATIONS 1.​ Heterotopic ossification (HO) -​ MC: ⭐ -​ SCI: Hip > knee > shoulder > elbow -​ CVA/TBI: Shoulder -​ BURNS: Posterolateral elbow -​ Increased Risk to occur HO: FORCEFUL PROM EXERCISES w/ px’s SPASTICITY 2.​ Fractures and osteoporosis -​ MC: supracondylar (distal femur)⭐ -​ Management: weight bearing (WOLFF’S LAW) 3.​ Pressure Ulcers / Bedsores -​ MC sites: -​ Supine - Sacrum -​ Sitting - Ischial tuberosity -​ Side lying - lateral malleolus -​ Infant - occiput -​ Management -​ Turning every 2 hours -​ Pressure relief activities -​ Interval: 15-30 mins -​ Duration: 13 - 30 secs 4.​ Deep Vein Thrombosis (DVT) ⭐ ⭐ -​ MC cause: Immobility ⭐ -​ MC complication: Pulmonary infarction -​ Special test: Homan’s test -​ VIRCHOW’S TRIAD: “hiv” ⭐ ⭐ -​ Hypercoagulability ⭐ -​ Intimal wall damage ⭐ -​ Venous stasis -​ Pharmacological management -​ Heparin & Warfarin Aira C. Gonzales, PTRP 5.​ Cardiopulmonary complications -​ Heart: Arrhythmia -​ Lungs: Pneumonia (MC cause of death) ⭐⭐ -​ 2nd MC cause of death: heart dse -​ 3rd MC cause of death: septicemia -​ MC complication: pulmo -​ Pneumonia -​ Atelectasis -​ Obstructive sleep apnea (OSA) -​ Management: -​ Intubation -​ Tracheostomy III. SCI ASSESSMENT A.​ASIA SCALE (American Spinal Cord Injury Association) Classification: SENSORY MOTOR A - Complete (-) (-) B- Sensory (+) SSS (-) incomplete C - Motor (+) SSS (+) VAC incomplete MMT: >50% (0-2/5) D - Motor (+) SSS (+) VAC incomplete MMT: >50% (3-5/5) E - Normal ⭐ N N Criteria for Sacral Sparing Sensory 1.​ Deep Anal Pressure (DAP) (S4-S5) 2.​ Light touch & Pressure (S4-S5) Motor 1.​ Voluntary Anal Contraction (VAC) a.​ Put finger to px’s anus and ask to contract *Complete SCI = (-) Sacral Sparing* *Incomplete SCI = (+) Sacral Sparing* Aira C. Gonzales, PTRP Scoring: Sensory: 2 - Normal 1 - Impaired / Altered 0 - Absent -​ Modalities: -​ Light touch (brush , cotton) -​ Pinprick (pointy end, paper clip) Motor - MMT 5 - Normal (N) = Full ROM w/ max. Resistance 4 - Good (G) = Full ROM w/ moderate resistance 3 - Fair (F) = Full ROM w/ against gravity 2 - Poor (P) = Active motion w/ gravity eliminated 1 - Trace (T) = Visible cxn 0 - zero (Z) = Absent / no cxn B. LEVEL OF CLASSIFICATION: ​ Sensory level (SL) - most caudal segment w/ normal sensation ​ Motor level (ML) - most caudal segment w/ at least ⅗ MMT w/ 5/5 MMT above the level ○​ NOTE: If there’s no corresponding myotome applicable, ○​ Myotome = Dermatome ​ Neurologic level of injury (NLI) - most caudal segment w/ normal sensation & motor. Sample 1: -​ Sensory: (L) ® Motor: (L) ® -​ C5 2 2 C5 5 5 -​ C6 2 2 C6 5 5 -​ C7 2 0 C7 4 3 -​ C8 1 0 C8 2 3 -​ SL: L = C7 ML: L = C7 -​ R = C6 R = C7 -​ Final = C6 Final = C7 -​ NLI = C6 Sample 2: -​ Sensory: (L) ® Motor: (L) ® -​ T11 2 2 T11 (-) (-) -​ T12 1 2 T12 (-) (-) -​ L1 0 0 L1 0 0 -​ SL: L = T11 ML: L = T11 -​ R = T12 R = T12 -​ Final = T11 Final = T11 -​ NLI = T11 Aira C. Gonzales, PTRP Sample 3: -​ Sensory: (L) ® Motor: (L) ® -​ C6 2 2 C6 5 5 -​ C7 1 2 C7 5 5 -​ C8 1 1 C8 3 2 -​ T11 0 1 T11 0 4 -​ SL: L = C6 ML: L = C8 -​ R = C7 R = C7 -​ Final = C6 Final = C7 -​ NLI = C6 C. DERMATOMES ⭐ Computations: ​ Number of strips - x 28 ​ Maximum score - x 2 ​ Number of modalities (Light touch & pp) - x 2 ​ Laterality - x 2 ​ PERFECT SCORE (MAXIMUM): 224 ⭐ Sample 1: ​ nipple - N (T4) ​ Medial knee - impaired (L3) ​ S4 - S5 - 0 -​ Solution: -​ *Per segment -​ C2 - C8 = 7 x 2 x 2 x 2 = 56 -​ T1 - T4 = 4 x 2 x 2 x 2 = 32 -​ T5 - T12 = 8 x 1 x 2 x 2 = 32 -​ L1 - L3 = 3 x 1 x 2 x 2 = 12 -​ Total: 132 -​ Or -​ C2 - T4 = 11 x 2 x 2 x 2 = 88 -​ T5 - L3 = 11 x 1 x 2 x 2 = 44 -​ Total: 132 Sample 2: ​ 6th ICS to umbilicus - impaired by ​ Below T10 - Absent -​ Solution: -​ C2 - C8 = 7 x 2 x 2 x 2 = 56 -​ T1 - T5 = 5 x 2 x 2 x 2 = 40 -​ T6 - T10 = 5 x 1 x 2 x 2 = 20 -​ Total: 116 Aira C. Gonzales, PTRP Sample 3: ​ Inguinal - normal ​ Dorsum of the foot - impaired -​ Solution: -​ C2 - C8 = 7 x 2 x 2 x 2 = 56 -​ T1 - T12 = 12 x 2 x 2 x 2 = 96 -​ L1 - L5 = 5 x 1 x 2 x 2 = 20 -​ Total: 172 -​ / 2 unilateral = 86 *132 / 2 (unilateral) = 66 D. MYOTOMES ⭐ Computations: ​ Muscle group - x 10 ​ Maximum score - x 5 ​ Laterality - x 2 ​ Total = 100 Sample 1: ​ Wrist extension - Normal (C6) ​ Wrist flex & elb ext - fair (C7) ​ Finger flex - Fair (C8) ​ Finger abd - poor (t1) -​ Solution: -​ C5 - C6 = 2 X 5 X 2 = 20 -​ C7 - C8 = 2 X 3 X 2 = 12 -​ T1 = 1 X 2 X 2 = 4 -​ L2 = 0 -​ L3 = 0 -​ L4 = 0 -​ L5 = 0 -​ S1 = 0 -​ TOTAL: 36 Sample 2: ​ Elb ext - Normal (C7) ​ Knee ext below - absent (L3) ​ The rest - Fair (L4) -​ Solution: -​ C5, C6, C7 = 3 X 5 X 2 = 30 -​ C8 , T1= 3 X 3 X 2 = 18 -​ L2 = 0 -​ L3 = 0 -​ L4 = 0 -​ L5 = 0 -​ S1 = 0 -​ TOTAL: 48 Aira C. Gonzales, PTRP IV. SCI REHABILITATION A.​Crutch walking muscles ⭐ 1.​ Latissimus dorsi -​ Exercise: SEATED PUSH UP ⭐ 2.​ Lower trapezius -​ Action: Depression ⭐ 3.​ Deltoid -​ Most important muscle for wheelie 4.​ Pectoralis Minor ⭐ 5.​ Pectoralis Major -​ Most important muscle for using parallel bars and handrails ⭐ -​ FADER ⭐ 6.​ Triceps brachii -​ Shoulder extensors, ER, Ant deltoid = Locking of elbow ⭐ 7.​ Anconeus -​ Elbow extension Initiator 8.​ Wrist extensors 9.​ Finger flexors (FDS & FDP) 10.​ Thumb flexors B.​Orthosis & AD ​ Upper extremity ○​ C1 - C4 = AFO (Arm Forearm Orthosis) ○​ C1 - C5 = Long Opponents ○​ C1 - C6 = RHS (Resting Hand Splint) ○​ C5 = BFO (Balance Forearm Orthosis) - For feeding ⭐ ○​ C6 = Flexor Hinge ○​ C5 - C7 = Universal Cuff ○​ C6 - C7 = Short Opponents ○​ C8 - T1 = Lumbrical Bar ​ Lower extremity ○​ T1 - T12 = KAFO w/ walker ⭐ ○​ L1 L3 = KAFO w/ crutches (lofstrand) ○​ L4 - L5 = AFO w/ crutches (lofstrand) or quad cane C.​Functional goals ​ C1 - C3 = “MPG” ​ Mechanical vent ​ Phrenic nerve stimulator ​ Glossopharyngeal breathing ​ C4 = “HNP” ○​ Head, mouth, tongue, chin, ⭐ sip & puff wheelchair control Aira C. Gonzales, PTRP ○​ No UE Fxn ⭐ ○​ Powered mobile arm support ​ C5 =“JOB” ○​ Joystick wheelchair control ○​ Oblique handrim wheelchair ⭐ ○​ Balance FA orthosis (BFO) - feeding ​ C6 “VAST” ○​ Vertical handrim wheelchair ⭐ ○​ ADL transfer w/ AD (sliding board , handrails, overhead trapeze) ⭐ ○​ Self care & driving w/ AD ○​ Tenodesix - ⭐ selective stretching ( Avoid: wrist & finger extension) ​ ⭐ ⭐ C7 - Friction handrim wheelchair ⭐ ○​ Self ROM (7) ○​ ADL independent w/o AD ​ Driving ​ Transfer ​ Feeding ​ Toileting ​ ⭐ C8 - Standard (8) wheelchair ○​ Self care (8) w/o AD ○​ Wheelies (8) *ADL Transfer* *Self care* *Driving* W/ - C6 W/ - C6 w/ - C6 W/o - C7 W/o - C8 w/o - C7 ​ T4 -T6 ○​ Physiologic standing ​ T6 - T9 ○​ Swing to gait ​ T9 - T12 ○​ Household ambulation ​ T12 - L2 ○​ Swing through gait ​ L2 - L3 ○​ Functional ambulation ​ L4 - L5 ○​ Community ambulation Conflicts: Book review!! 1.​ Drive(5) - C5 2.​ Hygiene (7) (dress & bathe) - C7 3.​ Community ambulation - L3 “communithree” Aira C. Gonzales, PTRP

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