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Chapter 2 The Molecules of Cells اﻟﺟزﯾﺋﺎت اﻟﺧﻠوﯾﺔ PowerPoint® Lecture Presentations for 41 Slides...
Chapter 2 The Molecules of Cells اﻟﺟزﯾﺋﺎت اﻟﺧﻠوﯾﺔ PowerPoint® Lecture Presentations for 41 Slides This presentation is NOT an Biology Alternative to the textbook Eighth Edition Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings Neil Campbell and Jane Reece Lectures by Chris Romero, updated by Erin Barley with contributions from Joan Sharp This Presentation is NOT an Alternative to the Textbook! ھذه اﻟﺷراﺋﺢ ھﻰ ﻋرض ﻣﺑﺳط ﻣﺗرﺟم ﻟﻠﻣﺳﺎﻋدة وﻟﯾﺳت ﻋرض ﺗﻔﺻﯾﻠﻰ ﻟﻠﻣوﺿوﻋﺎت اﻟﻣﻘررة ﻓﻰ ھذا اﻟﻔﺻل وﯾﺟب اﻟرﺟوع اﻟﻰ اﻟﻛﺗﺎب اﻟﺟﺎﻣﻌﻲ ﻟﻠﻣﻘرر. !This Presentation is NOT an Alternative to the Textbook Introduction to organic compounds Carbon-based molecules are called organic compounds. Methane (CH4) is the simplest organic compound ﺗﺗﻛون اﻟﺟزﯾﺋﺎت اﻟﻣﺧﺗﻠﻔﺔ اﻟﻣوﺟودة ﻓﻲ اﻟﺧﻠﯾﺔ ﻣن ﻛرﺑون ﻣرﺗﺑط ﺑﻌﻧﺎﺻر أﺧرى ﻣﺛل اﻟﻣﯾﺛﺎن وھو أﺣد أﺑﺳط اﻟﻣرﻛﺑﺎت اﻟﻌﺿوﯾﺔ This Presentation is NOT an Alternative to the Textbook! – Carbon can bond to four other atoms and branch Life’s molecular to four directions. Itdiversity is based may form chains on or rings. theاﻟﻛرﺑون اﻟﺗﻔرع إﻟﻰ properties أﺧرى وﯾﺳﺗطﯾﻊ ﺑذﻟكof ذراتcarbon ﯾﺳﺗطﯾﻊ اﻟﻛرﺑون اﻻرﺗﺑﺎط ﺑﺄرﺑﻊ –.أرﺑﻌﺔ إﺗﺟﺎھﺎت ﻣﻛوﻧﺎ ﺳﻼﺳل أو ﺣﻠﻘﺎت – Compounds composed of only carbon and hydrogen are called hydrocarbons. ﯾﺳﻣﻰ ﻛل ﻣن اﻟﻣﯾﺛﺎن واﻟﻣرﻛﺑﺎت اﻟﻣؤﻟﻔﺔ ﻣن ﻛرﺑون وھﯾدروﺟﯾن ﻓﻘط – ﺑﺎﻟﮭﺎﯾدروﻛرﺑوﻧﺎت Ethane Methane This Presentation is NOT an Alternative to the Textbook! Functional groups: groups of atoms that participate in chemical reactions and determine the properties of organic compound. :ﺗﻌﻤﻞ اﻟﻤﺠﺎﻣﯿﻊ اﻟﻜﯿﻤﯿﺎﺋﯿﺔ اﻟﻤﺘﻤﯿﺰة ﻋﻠﻰ ﺗﺤﺪﯾﺪ ﺻﻔﺎت اﻟﻤﺮﻛﺒﺎت اﻟﻌﻀﻮﯾﺔ ﻣﺜﺎل ﻟﺬﻟﻚ This Presentation is NOT an Alternative to the Textbook! (4) classes Cells make a molecules of large huge number important to of large organisms: molecules from a اﻟﺟزﯾﺋﺎت اﻟﺣﯾوﯾﺔ smallﻣنset أﺻﻧﺎفofأرﺑﻌﺔsmall ھﻧﺎك molecules Carbohydrates* اﻟﻜﺮﺑﻮھﯿﺪرات Proteins* اﻟﺒﺮوﺗﯿﻨﺎت Lipids* (اﻟﻠﺒﯿﺪات )اﻟﺪھﻮن Nucleic acid* اﻷﺣﻤﺎض اﻟﻨﻮوﯾﺔ These are called large molecules or Macromolecules or Polymers This Presentation is NOT an Alternative to the Textbook! Polymers are broken down to smaller molecules called monomers by a process, hydrolysis (addition of water molecule) 1 2 3 4 Polymer Addition of water molecule 1 2 3 This Presentation is NOT an Alternative to the Textbook! monomer Dehydration reactions build a polymer chain ﺑﻧﺎء ﺳﻠﺳﻠﺔ ﺑوﻟﯾﻣﯾر ﺑﺗﻔﺎﻋﻼت ﻧزع اﻟﻣﺎء Short polymer Monomer ﺑوﻟﯾﻣﯾر ﻗﺻﯾر ﻣوﻧﯾﻣﯾر ﻏﯾر ﻣرﺗﯾط Dehydration Reaction ﺗﻔﺎﻋل ﻧزع اﻟﻣﺎء Longer polymer ﺑوﻟﯾﻣﯾر طوﯾل This Presentation is NOT an Alternative to the Textbook! 1- Carbohydrates اﻟﻜﺮﺑﻮھﯿﺪرات The term carbohydrate was originally used to describe compounds that had the formula CH2O. Carbohydrates range from small simple sugars (monosaccharides) to large complex sugars (polysaccharides) ﺗﺗﻧوع اﻟﻛرﺑوھﯾدرات ﻓﻲ اﻟﺣﺟم ﺑداً ﺑﺟزﯾﺋﺎت اﻟﺳﻛر اﻟﺑﺳﯾطﺔ اﻟﺻﻐﯾرة )اﻟﺳﻛرﯾﺎت اﻷﺣﺎدﯾﺔ( وﺣﺗﻰ اﻟﺳﻛﺎﻛراﻟﻛﺑﯾرة (اﻟﻣﻌﻘدة (اﺳﻛﺎﻛراﻟﻣﺗﻌددة Carbohydrates contain (3) major categories of molecules: monosaccharides, disaccharides, and polysaccharides. This Presentation is NOT an Alternative to the Textbook! 1- Carbohydrates اﻟﻜﺮﺑﻮھﯿﺪرات Carbohydrates range from small sugars (monosaccharides) to large sugars (polysaccharides) ﺗﺘﻨﻮع اﻟﻜﺮﺑﻮھﯿﺪرات ﻓﻲ اﻟﺤﺠﻢ ﺑﺪاً ﺑﺠﺰﯾﺌﺎت اﻟﺴﻜﺮ اﻟﺼﻐﯿﺮة )اﻟﺴﻜﺮﯾﺎت اﻷﺣﺎدﯾﺔ( وﺣﺘﻰ (اﻟﺴﻜﺎﻛﺮاﻟﻜﺒﯿﺮة (اﻟﺴﻜﺎﻛﺮاﻟﻤﺘﻌﺪدة This Presentation is NOT an Alternative to the Textbook! Monosaccharides are the fuels for cellular work have a Monosaccharides formula that contains hydroxylare the group simplest (OH) and a carbonyl group carbohydrates (CO) and is a multiple of CH2O. Sugar monosaccharides include: Glucose – Fructose – Galactose – Ribose (in RNA) & Deoxyribose (DNA). Glucose and fructose are isomers that contain the same number of atoms (6 carbon long) but in different arrangements. ﯾﺗﻧوع اﻟﮭﯾﻛل اﻟﻛرﺑوﻧﻲ ﻟﻠﺳﻛﺎﻛر اﻷﺣﺎدﯾﺔ ﻓﻲ طوﻟﮫ ﻓﻣﺛﻼ ﯾﺑﻠﻎ طول ﻛل ﻣن ﺳﻛر اﻟﺟﻠوﻛوز وﺳﻛر اﻟﻔروﻛﺗوز ﺳﺗﺔ ذرات ﻛرﺑون وﻟﻛن ﻓﻰ ﺗرﺗﯾب ﻣﺧﺗﻠف This Presentation is NOT an Alternative to the Textbook! www.sparknotes.com Two monosaccharides are linked to form a disaccharide. Examples of Disaccharides: Sucrose (table sugar or cane sugar) : glucose + fructose Maltose : glucose + glucose Lactose (milk sugar) : glucose + galactose This Presentation is NOT an Alternative to the Textbook! Polysaccharides are complex carbohydrates composed of numerous monosaccharides combined through the loss of water molecules. Starch and glycogen are polysaccharides composed of glucose monomers. اﻟﻧﺷﺎ واﻟﺟﻠﯾﻛوﺟﯾن ﻋﺑﺎرة ﻋن ﺳﻛرﻣﺗﻌدد ﺗﺧزﯾﻧﻲ (ﻟﻠطﺎﻗﺔ( وﯾﺗﻛون ﻣن ﻣوﻧﯾﻣﯾرات ﺟﻠوﻛوز Starch & glycogen are used by plants & animal for energy (storage carbohydrates). اﻟﻧﺷﺎ ﯾوﺟد ﻓﻲ اﻟﻧﺑﺎت واﻟﺟﻠﯾﻛوﺟﯾن ھو اﻟﻧﺷﺎ اﻟﺣﯾواﻧﻰ وﯾﺳﺗﺧدم ﻛﻠﯾﮭﻣﺎ ﻛﻣﺻدر ﻟﻠطﺎﻗﺔ Cellulose and chitin are polysaccharides which form plant cell walls and insects exoskeleton (protective polysaccharides). اﻟﺳﯾﻠﯾﻠوز ﻋﺑﺎرة ﻋن ﺳﻛر ﻣﺗﻌدد ﯾﻛون ﺟدر اﻟﺧﻼﯾﺎ ﻓﻲ اﻟﻧﺑﺎﺗﺎت و اﻟﻛﯾﺗﯾن ﻋﺑﺎرة ﻋن ﺳﻛر ﻣﺗﻌدد.(ﯾدﺧل ﻓﻰ ﺗرﻛﯾب اﻟﮭﯾﺎﻛل اﻟﺧﺎرﺟﯾﺔ ﻟﻠﺣﺷرات واﻟﻘﺷرﯾﺎت )ﻓﻰ اﻟﺣﻣﺎﯾﺔ This Presentation is NOT an Alternative to the Textbook! Lipids Lipids Lipids include are a group fats, of naturally which occurring are mostly molecules are a group of naturallyenergy-storage occurring molecules thatmolecules اﻟﻠﺒﯿﺪات include fats are a group of naturally occurring molecules that include fats, waxes are a group of naturally occurring molecules that include fats, waxes, sterols are a group of naturally occurring molecules that include fats, waxes, sterols, fat-soluble vitamins are a group of naturally occurring molecules that include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E, and, K), triglycerides are a group of naturally occurring molecules that include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E, and, K), triglycerides, phospholipids are a group of naturally occurring molecules that include fats, waxes, sterols, This Presentation is NOT an Alternative to the Textbook! fat-soluble vitamins (such as vitamins A, D, E, and, K), triglycerides, phospholipids. The main biological functions of lipids include storing energy, signaling, and acting as structural components of cell membranes Lipids composed largely of carbon and hydrogen. Lipids contain twice the energy as a polysaccharide has. اﻟﻠﺒﯿﺪات ھﺎﻣﺔ ﻓﻲ ﺗﺨﺰﯾﻦ اﻟﻄﺎﻗﺔ ﺣﯿﺚ ﺗﺤﺘﻮى ﻋﻠﻰ ﺿﻌﻒ اﻟﻄﺎﻗﺔ اﻟﻤﻮﺟﻮدة ﺑﺎﻟﺴﻜﺮﯾﺎت اﻟﻌﺪﯾﺪة Lipids do not mix with water (insoluble in water = hydrophobic) ( اﻟﻠﺒﯿﺪات ھﻲ ﻣﺮﻛﺒﺎت ﻻ ﺗﺨﺘﻠﻂ )ﻻ ﺗﺬوب( ﻓﻲ اﻟﻤﺎء )ﻛﺎرھﺔ ﻟﻠﻤﺎء 3 types of lipids: ﺛﻼث أﻧواع ﻣن اﻟﻠﺑﯾدات LIPIDS اﻟﻠﺑﯾدات True Fats Phospholipids Steroids اﻟدھون اﻟﺣﻘﯾﻘﯾﺔ اﻟدھون اﻟﻔﺳﻔورﯾﺔ اﻻﺳﺗﯾروﯾدات Copyright © 2009 Pearson Education, Inc. This Presentation is NOT an Alternative to the Textbook! Fats are large lipids made from glycerol and fatty acids. Fats main function is energy storage. اﻟدھون )اﻟﺳﻣن واﻟزﺑدة واﻟزﯾت( ﻧوع ﻣن اﻟﻠﺑﯾدات ﻣﻛوﻧﺔ ﻣن ﺟﻠﯾﺳﯾرول وأﺣﻣﺎض دھﻧﯾﺔ Example: Triglycerides اﻟدھون اﻟﺛﻼﺛﯾﺔare fat molecules consist of one glycerol molecule linked to three fatty acids اﻟدھن اﻟذى ﯾﺣﺗوى ﻋﻠﻰ ﺟﻠﯾﺳﯾرول ﻣرﺗﺑط ﺑﺛﻼث أﺣﻣﺎض دھﻧﯾﺔ ﻋﺎدة ﻣﺎ ﺗﺳﻣﻰ ھذة اﻟدھون ﺑﺎﻟﺟﯾﻠﯾﺳرﯾدات اﻟﺛﻼﺛﯾﺔ ﺑﺳﺑب ھذا اﻟﺗرﻛﯾب In human body, high levels of triglycerides in the bloodstream have been linked to arteriosclerosis ﺗﺻﻠب اﻟﺷراﯾﯾنand, by time, the risk of heart disease أﻣراض اﻟﻘﻠبand stroke اﻷزﻣﺔ اﻟﻘﻠﺑﯾﺔ This Presentation is NOT an Alternative to the Textbook! Glycerol C3H5O3 A Triglyceride molecule made from glycerol and 3 fatty acids ﺟزﯾﺊ دھن ﻣﻛون ﻣن ﺟﯾﻠﯾﺳرول وﺛﻼث أﺣﻣﺎض دھﻧﯾﺔ 3 fatty acids C55H98O6 This Presentation is NOT an Alternative to the Textbook! C55 H98 O6 This Presentation is NOT an Alternative to the Textbook! Fatty acidsFatty acids, are made of a hydrocarbon chainFatty acids, are made of a hydrocarbon chain that terminates with a carboxylic acid group.The fatty acid structure is one of the most fundamental categories of biological lipids, and is commonly used as a building-block of more structurally complex lipids. Fatty acids are either: 1) Saturated fatty acids دھون ﻣﺷﺑﻌﺔ * The hydrocarbon chain without double bond (=). * Solid at room temperature. * High melting point. * Occur in most animal fats. 2) Unsaturated fatty acids دھون ﻏﯾر ﻣﺷﺑﻌﺔ * The hydrocarbon chain contain one or more double bonds. * Liquid at room temperature. * Low melting point. This Presentation is NOT an Alternative to the*Textbook! Occur in most plant cells. Phospholipids are class of lipids structurally similar to fats and a major (key) component of biological membranes (cell membranes) اﻟﻠﺑﯾدات اﻟﻔﺳﻔورﯾﺔ دھون ﻣن اﻟﻣﻛوﻧﺎت اﻷﺳﺎﺳﯾﺔ ﻟﻠﻐﺷﺎء اﻟﺧﻠوى ﺣﯾث ﺗﺗﺟﻣﻊ ﻋﻠﻰ ﺷﻛل طﺑﻘﺗﯾن Phospholipids contain (2) fatty acids attached to glycerol. ﺗﺘﻜﻮن اﻟﻠﺒﯿﺪات اﻟﻔﻮﺳﻔﻮرﯾﺔ ﻣﻦ ﺣﻤﻀﯿﯿﻦ دھﻨﯿﯿﻦ ﻣﻊ ﺟﻠﯿﺴﺮول Section of a phospholipid membrane ﻗطﺎع ﻓﻲ ﻏﺷﺎء ﻟﺑﯾدي ﻓﺳﻔوري اﻟﺳطﺢ اﻟﺧﺎرﺟﻲ Hydrophilic Waterﻣﺎء ﻟﻠﺧﻠﯾﺔ heads Cell external رؤس ﻣﺣﺑﺔ ﻟﻠﻣﺎء surface Hydrophobic tails ذﯾول ﻛﺎرھﺔ ﻟﻠﻣﺎء اﻟﺳطﺢ اﻟداﺧﻠﻲ ﻟﻠﺧﻠﯾﺔ Waterﻣﺎء Cell internal surface This Presentation is NOT an Alternative to the Textbook! Connection: Steroids (stereos Anabolic steroids = solid) are lipids in which and carbon related skeleton contains substances (4) fused rings. pose health risksاﻷﺳﺘﺮوﯾﺪات ﻋﺒﺎرة ﻋﻦ دھﻮن ﻣﻜﻮﻧﺔ ﻣﻦ أرﺑﻊ ﺣﻠﻘﺎت ﺗﺮﻛﯿﺒﯿﺔ ﻣﺘﺪاﺧﻠﺔ Examples of steroids include: - Lipid- Lipid cholesterol - Sex hormones estradiolSex hormones estradiol (female) and testosterone (male). Cholesterol is an example of steroids and is an essential structural component of animal cell membranes. اﻟﻜﻮﻟﯿﺴﺘﺮول (ﻣﻦ اﻟﺪھﻮن( ھﻮ ﻣﺜﺎل ﻟﻼﺳﺘﺮوﯾﺪات اﻟﺘﻲ ﺗﻠﻌﺐ دوراً ھﺎﻣﺎ ً ﻓﻲ ﺗﺮﻛﯿﺐ ﻏﺸﺎء اﻟﺨﻠﯿﺔ اﻟﺤﯿﻮاﻧﻰ This Presentation is NOT an Alternative to the Textbook! This Presentation is NOT an Alternative to the Textbook! Anabolic steroids are drugs that have similar effects to testosterone (steroid male hormone) in the body. They increase protein within cells, especially in skeletal muscles (buildup muscles). ﺳﺘﺮوﯾﺪات اﻷﯾﺾ اﻟﺒﻨﺎﺋﻲ ﻋﺒﺎرة ﻋﻦ ﻋﻘﺎر ذو ﺗﻮﻟﯿﻔﺔ ﺻﻨﺎﻋﯿﺔ ﻣﻦ اﻟﺘﯿﺴﺘﯿﺴﺘﺮوﻧﺎت )ھﺮﻣﻮﻧﺎت ذﻛﻮرة اﺳﺘﯿﺮودﯾﺔ( واﻟﺘﻲ ﺗﺆدي ﻟﺒﻨﺎء اﻟﻜﺘﻠﺔ اﻟﻌﻀﻠﯿﺔ واﻟﻌﻈﻤﯿﺔ Use of these substances can cause serious health problems such as liver damage and high blood pressure. وﯾﻤﻜﻦ أن ﯾﺆدي ﺳﻮء إﺳﺘﮭﻼﻛﮭﺎ إﻟﻰ ﻧﺘﺎﺋﺞ وﺧﯿﻤﺔ ﻣﺜﻞ اﻟﻔﺸﻞ اﻟﻜﺒﺪي اﻟﺬي ﯾﻤﻜﻦ أن ﯾﺆدي ﻟﻠﺴﺮطﺎن This Presentation is NOT an Alternative to the Textbook! Proteins اﻟﺒﺮوﺗﯿﻨﺎت - Proteins are large biological molecules. Proteins perform a vast array of functions within living organisms..اﻟﺒﺮوﺗﯿﻨﺎت ﺟﺰﯾﺌﺎت ﺑﯿﻮﻟﻮﺟﯿﺔ ﻛﺒﯿﺮة ﺗﻘﻮم ﺑﺄدوار ﻣﺘﻨﻮﻋﺔ ﻓﻰ اﻟﻜﺎﺋﻦ اﻟﺤﻰ - - Tens of thousands of different proteins are found in your body. The most important are enzymes that speed up all reactions in cells ﻋﺸﺮات اﻷﻻف ﻣﻦ اﻟﺒﺮوﺗﯿﻨﺎت ﻣﻮﺟﻮدة ﺑﺎﻟﺠﺴﻢ أھﻤﮭﺎ اﻻﻧﺰﯾﻤﺎت اﻟﺘﻰ ﺗﺴﺮع ﻣﻦ -.اﻟﺘﻔﺎﻋﻼت اﻟﻜﯿﻤﯿﺎﺋﯿﺔ داﺧﻞ اﻟﺨﻠﯿﺔ - Proteins are polymers of amino acids joined together by peptide bonds. There are 20 different amino acids (building blocks of proteins) that make up essentially all proteins on earth. Thus, the characteristic that distinguishes one amino acid from another is its unique side chain. This Presentation is NOT an Alternative to the Textbook! - Each of these amino acids has a fundamental design composed of a central carbon (also called the alpha carbon) bonded to: :اﻷﺣﻤﺎض اﻷﻣﯿﻨﯿﺔ (اﻟﻮﺣﺪات اﻟﺒﻨﺎﺋﯿﺔ ﻟﻠﺒﺮوﺗﯿﻦ) وﯾﺘﻜﻮن ﻛﻞ ﺣﻤﺾ أﻣﯿﻨﻰ ﻣﻦ - - a carboxyl group (COOH): makes it an acid ﻣﺠﻤﻮﻋﺔ ﻛﺮﺑﻮﻛﺴﯿﻞ - an amino group (NH2) - a unique side chain or R-group: Distinguishes each of the (20) different amino acids General structure of an amino acid اﻟﺗرﻛﯾب اﻟﻌﺎم ﻟﻠﺣﻣض اﻷﻣﯾﻧﻲ Amino Carboxyl Group group ﻣﺟﻣوﻋﺔ أﻣﯾن ﻣﺟﻣوﻋﺔ ﻛرﺑوﻛﺳﯾل This Presentation is NOT an Alternative to the Textbook! Proteins are either: Structural Proteins ﺑﺮوﺗﯿﻨﺎت ﺗﺮﻛﯿﺒﯿﺔ: Proteins in fibers that make tendons & اﻷوﺗﺎر ligaments اﻷرﺑﻄﺔ Defensive Proteins ﺑﺮوﺗﯿﻨﺎت دﻓﺎﻋﯿﺔ: Antibodies اﻻﺟﺴﺎم اﻟﻤﻀﺎدةof the immune system ﻟﻠﺠﮭﺎز اﻟﻤﻨﺎﻋﻰ Signal Proteins (communication) ﺑﺮوﺗﯿﻨﺎت اﺷﺎرﯾﺔ: Hormones اﻟﮭﺮﻣﻮﻧﺎت Transport Proteins اﻟﺒﺮوﺗﯿﻨﺎت اﻟﻨﺎﻗﻠﺔ: Haemoglobin ﺟﺰئ اﻟﮭﯿﻤﻮﺟﻠﻮﺑﯿﻦin red blood cells ﺧﻼﯾﺎ اﻟﺪم اﻟﺤﻤﺮاء This Presentation is NOT an Alternative to the Textbook! Storage Proteins اﻟﺒﺮوﺗﯿﻨﺎت اﻟﺨﺎزﻧﺔ: Protein found in: Plant seed - egg white ﺑﯿﺎض اﻟﺒﯿﺾ- milk A protein shape depends on (4) levels of structure ﯾﻤﻜﻦ أن ﯾﻜﻮن ﻟﻠﺒﺮوﺗﯿﻦ أرﺑﻌﺔ ﻣﺴﺘﻮﯾﺎت ﻣﻦ اﻟﺘﺮﻛﯿﺐ – Primary structureاﻟﺘﺮﻛﯿﺐ اﻻوﻟﻰ Primary structure is a unique sequence of amino acids. – Secondary structureاﻟﺘﺮﻛﯿﺐ اﻟﺜﺎﻧﻮي Polypeptide chain can fold back on itself in a number of ways give secondary structure called alpha helix. – Tertiary structureاﻟﺘﺮﻛﯿﺐ اﻟﺜﻼﺛﻲ The term tertiary refers to folding of peptide chain in three dimension giving final three dimensional shape of a protein. – Quaternary structure اﻟﺘﺮﻛﯿﺐ اﻟﺮﺑﺎﻋﻲ Protein consists of 2 or more polypeptide chains and quaternary structure results from association of four protein subunits. This Presentation is NOT an Alternative to the Textbook! Hemoglobin and collagen has quaternary structure This Presentation is NOT an Alternative to the Textbook! اﻟﺤﺎﻣﺾ اﻟﻨﻮوى Nucleic acid ) DNA (Deoxyribonucleic acid) and RNA (ribonucleic acid are the 2 types of nucleic acid. اﻟﺪﻧﺎ ) ﺣﻤﺾ اﻟﺮﯾﺒﻮز اﻟﻨﻮوي اﻟﻤﻨﺰوع اﻷوﻛﺴﺠﯿﻦ ( و اﻟﺮﻧﺎ ) ﺣﻤﺾ اﻟﺮﯾﺒﻮز اﻟﻨﻮوي ( ھﻤﺎ ﻧﻮﻋﻰ اﻟﺤﻤﺾ اﻟﻨﻮوى Nucleic acids (DNA or RNA)are composed of nucleotides. ﺗﺘﻜﻮن اﻷﺣﻤﺎض اﻟﻨﻮوﯾﺔ )ﺣﻤﺾ اﻟﺪﻧﺎ( و ) ﺣﻤﺾ اﻟﺮﻧﺎ( ﻣﻦ وﺣﺪات ﺑﻨﺎﺋﯿﺔ ﺑﺴﯿﻄﺔ ھﻰ اﻟﻤﻮﻧﯿﻤﯿﺮات وﺗﺴﻤﻰ ﺑﺎﻟﻨﯿﻮﻛﻠﯿﻮﺗﯿﺪات - A nucleotide is composed of (3) parts: -ﺗﺘﻜﻮن ﻛﻞ ﻧﯿﻮﻛﻠﯿﻮﺗﯿﺪة ﻣﻦ ﺛﻼث أﺟﺰاء رﺋﯿﺴﯿﺔ: !This Presentation is NOT an Alternative to the Textbook - 5–Carbon Sugar (pentose sugar) called ribose in RNA and deoxy-ribose in DNA ﺳﻜﺮ ﺧﻤﺎﺳﻲ اﻟﻜﺮﺑﻮن ﯾﺴﻤﻰ ﺑﺎﻟﺮﯾﺒﻮز ﻓﻲ اﻟﺮﻧﺎ واﻟﺪﯾﻮﻛﺴﻲ رﯾﺒﻮز )ﻣﻨﺰوع- اﻷوﻛﺴﺠﯿﻦ( ﻓﻲ اﻟﺪﻧﺎ - Phosphate group ﻣﺟﻣوﻋﺔ ﻓوﺳﻔﺎت - Nitrogenous bases ﻗواﻋد ﻧﯾﺗروﺟﯾﻧﯾﺔ nucleotide اﻟﻧﯾوﻛﻠﯾوﺗﯾدة Nitrogenous base (Example: adenine) ﻗﺎﻋدة ﻧﯾﺗروﺟﯾﻧﯾﺔ ( اﻷدﻧﯾن:)ﻣﺛﺎل Phosphate Group ﻣﺟﻣوﻋﺔ ﻓوﺳﻔﺎت Pentose Sugar This Presentation is NOT an Alternative to the Textbook! ﺳﻛرﺧﻣﺎﺳﻰ This Presentation is NOT an Alternative to the Textbook! ▫ A sugar-phosphate backbone is formed by covalent bonding between the phosphate of one nucleotide and the sugar of the next nucleotide ﯾﺗﻛون ﻋﻣود اﻟﺳﻛر واﻟﻔوﺳﻔﺎت ﺑﺎﻻرﺗﺑﺎط اﻟﺗﺳﺎھﻣﻲ ﺑﯾن ﻓوﺳﻔﺎت إﺣدى اﻟﻧﯾوﻛﻠﯾوﺗﯾدات و ﺳﻛر اﻟﻧﯾوﻛﻠﯾوﺗﯾدة اﻟﺗﺎﻟﯾﺔ ▫ Nitrogenous bases extend from sugar-phosphate backbone ﺗﺑرز اﻟﻘواﻋد اﻟﻧﯾﺗروﺟﯾﻧﯾﺔ ﻣن ﻋﻣود اﻟﺳﻛر واﻟﻔوﺳﻔﺎت اﻟﻘواﻋد اﻟﻧﯾﺗروﺟﯾﻧﯾﺔ اﻟﻘواﻋد اﻟﻧﯾﺗروﺟﯾﻧﯾﺔ This Presentation is NOT an Alternative to the Textbook! This Presentation is NOT an Alternative to the Textbook! DNA consists of (2) poly-nucleotides twisted around each other in a helix ﯾﺗﻛون ﺟزئ اﻟدﻧﺎ ﻣن ﺳﻠﺳﻠﺗﯾن ﻋدﯾدة اﻟﻧﯾوﻛﻠﯾﺗﯾدات ﻣﻠﻔوﻓﺗﯾن ﻋﻠﻰ ﺑﻌﺿﮭﻣﺎ ﻓﻰ ﺷﻛل ﺣﻠزون Sequence of the four nitrogenous bases in DNA carry the genetic information ﺗﺳﻠﺳل اﻟﻘواﻋد اﻟﻧﯾﺗروﺟﯾﻧﯾﺔ ﻓﻰ ﺣﻣض اﻟدﻧﺎ ﯾﺣﻣل اﻟﺷﻔرة اﻟوراﺛﯾﺔ DNA programs cell activities by directing synthesis of protein ﯾﺗﺣﻛم ﺣﻣض اﻟدﻧﺎ ﻓﻰ أﻧﺷطﺔ اﻟﺧﻠﯾﺔ وﯾوﺟﺔ اﻟﺧﻠﯾﺔ ﻟﺑﻧﺎء اﻟﺑروﺗﯾن DNA information is transcribed into RNA, a single-stranded nucleic acid, information on RNA is then translated into proteins ﺗﻧﺳﺦ اﻟﻣﻌﻠوﻣﺎت ﻓﻰ ﺣﻣض اﻟدﻧﺎ اﻟﻰ ﺣﻣض اﻟرﻧﺎ ﺛم ﺗﺗرﺟم اﻟﻰ اﻟﺑروﺗﯾن A particular nucleotide sequence on a DNA that can instruct is called a gene ﺗطﻠق ﻛﻠﻣﺔ اﻟﺟﯾن ﻋﻠﻰ أى ﺗﺳﻠﺳل ﻧﯾوﻛﻠﯾوﺗﯾدي ﻣﻌﯾن ﻗﺎدر ﻋﻠﻰ ﺗوﺟﯾﮫ ﺑﻧﺎء ﻣﺗﻌدد اﻟﺑﯾﺑﺗﯾدات This Presentation is NOT an Alternative to the Textbook! This Presentation is NOT an Alternative to the Textbook! ﺗﻌﺮﯾﻒ اﻟﻤﺼﻄﻠـــــﺢ اﻟﻣﺻطﻠــــــــــــــﺢ Matter اﻟﻣﺎدة ﻋﺑﺎرة ﻋن أي ﺷﺊ ﻟﮫ ﻛﺗﻠﺔ )وزن( وﯾﺷﻐل ﺣﯾزاً ﻣﺎ Matter Is Composed Of Chemical ﺗﺗﻛون اﻟﻣﺎدة ﻣن ﻋﻧﺎﺻر ﻛﯾﻣﯾﺎﺋﯾﺔ Elements Element اﻟﻌﻧﺻر – )ھو اﻟﻣﺎدة اﻟﺗﻲ ﻻ ﯾﻣﻛن إﻧﺣﻼﻟﮭﺎ ﻟﻣواد أﺧرى( Essential Elements اﻟﻌﻧﺎﺻر اﻟﺿرورﯾﺔ )ﺗوﺟد داﺋﻣﺎ ً وأﺑداً ﻓﻲ أي ﻛﺎﺋن ﺣﻲ( اﻟﻣرﻛب )ھو ﻣﺎدة ﺗﺗﺄﻟف ﻣن إﺛﻧﯾن أو اﻛﺛر ﻣن اﻟﻌﻧﺎﺻر اﻟﻣﺧﺗﻠﻔﺔ Compound واﻟﺗﻲ ﺗرﺗﺑط ﺑﻧﺳب ﺛﺎﺑﺗﺔ( Atom اﻟذرة ھﻲ أﺻﻐر وﺣدة ﻓﻲ اﻟﻣﺎدة ﺗﺣﺗﻔظ ﺑﺧﺻﺎﺋص اﻟﻌﻧﺻر Proton اﻟﺑروﺗون )وﺣﯾد اﻟﺷﺣﻧﺔ اﻟﻛﮭرﺑﯾﺔ اﻟﻣوﺟﺑﺔ( Electron اﻹﻟﯾﻛﺗرون )وﺣﯾد اﻟﺷﺣﻧﺔ اﻟﻛﮭرﺑﯾﺔ اﻟﺳﺎﻟﺑﺔ( Neutron اﻟﻧﯾوﺗرون )ﻣﺗﻌﺎدل ﻛﮭرﺑﯾﺎ ً( Inorganic ﻏﯾر ﻋﺿوﯾﺔ Organic ﻋﺿوﯾﺔ A Covalent Bond results when Atoms ﺗﻧﺷﺄ اﻟراﺑطﺔ اﻟﺗﺳﺎھﻣﯾﺔ ﻋﻧدﻣﺎ ﺗﺷﺗرك اﻟذرات ﻓﻲ اﻟﯾﻛﺗروﻧﺎت اﻟﻣدار share outer-shell electrons اﻟﺧﺎرﺟﻲ ﯾﺗﻛون اﻟﺟزﯾﺊ ﺣﯾﻧﻣﺎ ﺗﺗﻣﺎﺳك اﻟذرات ﺑﺑﻌﺿﮭﺎ اﻟﺑﻌض ﺑواﺳط رواﺑط A Molecule is formed when atoms are held together by covalent bonds ﺗﺳﺎھﻣﯾﺔ !This Presentation is NOT an Alternative to the Textbook ﺗﻌﺮﯾﻒ اﻟﻤﺼﻄﻠـــــﺢ اﻟﻣﺻطﻠــــــــــــــﺢ )Organic Compounds (Molecules ﻣدﺧل ﻟﻠﻣرﻛﺑﺎت)اﻟﺟزﯾﺋﺎت( اﻟﻌﺿوﯾﺔ Organic Compounds ﺗﺳﻣﻰ اﻟﺟزﯾﺋﺎت اﻟﺗﻲ أﺳﺎﺳﮭﺎ ذرة اﻟﻛرﺑون ﺑﺎﻟﻣرﻛﺑﺎت اﻟﻌﺿوﯾﺔ ﯾﺳﻣﻰ ﻛل ﻣن اﻟﻣﯾﺛﺎن واﻟﻣرﻛﺑﺎت اﻟﻣؤﻟﻔﺔ ﻣن ﻛرﺑون وھﯾدروﺟﯾن Hydrocarbons ﻓﻘط ﺑﺎﻟﮭﺎﯾدروﻛرﺑوﻧﺎت Carbon Skeleton ﺗﺳﻣﺳﻰ ﺳﻠﺳﻠﺔ ذرات اﻟﻛرﺑون ﺑﺎﻟﮭﯾﻛل اﻟﻛرﺑوﻧﻲ Carbon Skeletons can be branched or ﻗد ﯾﺗﻔرع اﻟﮭﯾﻛل اﻟﻛرﺑوﻧﻲ أو ﻻ ﯾﺗﻔرع unbranched Isomers اﻟﻧظﺎﺋر ﺗؤﺛر اﻟﻣﺟﻣوﻋﺔ اﻟوظﯾﻔﯾﺔ ﻓﻲ وظﯾﻔﺔ اﻟﺟزﯾﺊ اﻟﺣﯾوي ﺑطرﯾﻘﺔ Functional Group ﻣﻣﯾزة )Hydrophilic (Water-Loving اﻟﻣرﻛﺑﺎت اﻟﻣﺣﺗوﯾﺔ ﻋﻠﻰ ﻣﺟﺎﻣﯾﻊ وظﯾﻔﯾﺔ ﺗﻛون ﻣﺣﺑﺔ ﻟﻠﻣﺎء This means that they are soluble in water, ﯾﻌﻧﻲ ھذا أﻧﮭﺎ ﺗذوب ﻓﻲ اﻟﻣﺎء وھذا ﻣﺗطﻠب ﺿروري ﻟﻠﻘﯾﺎم which is a necessary prerequisite for their ﺑوظﺎﺋﻔﮭﺎ اﻟﺣﯾوﯾﺔ اﻟﻣﻌﺗﻣدة ﻋﻠﻰ اﻟﻣﺎء roles In water-based life Hydroxyl Group—consists of a ﻣﺟﻣوﻋﺔ اﻟﮭﯾدروﻛﺳﯾل – ﺗﺗﻛون ﻣن ھﯾدروﺟﯾن ﻣرﺗﺑط ﺑﺄوﻛﺳﺟﯾن hydrogen bonded to an oxygen !This Presentation is NOT an Alternative to the Textbook ﺗﻌﺮﯾﻒ اﻟﻤﺼﻄﻠـــــﺢ اﻟﻣﺻطﻠــــــــــــــﺢ Carbonyl Group—A carbon linked by a ﻣﺟﻣوﻋﺔ اﻟﻛرﺑوﻧﯾل – ﻛرﺑون ﻣﺗﺻل ﺑذرة أوﻛﺳﺟﯾن ﺑراﺑطﺔ double bond to an oxygen atom ﺛﻧﺎﺋﯾﺔ Carboxyl Group—Consists of a carbon ﻣﺟﻣوﻋﺔ ﻛرﺑوﻛﺳﯾل – ﺗﺗﺄﻟف ﻣن ﻛرﺑون ﻣرﺗﺑط ﺑﻣﺟﻣوﻋﺔ bonded to A hydroxyl group and اﻟﮭﯾدروﻛﺳﯾل ﻛﻣﺎ وﺗرﺗﺑط ﺑراﺑطﺔ ﺛﻧﺎﺋﯾﺔ ﺑﺎﻷوﻛﺳﺟﯾن double-bonded to an oxygen Amino Group—Composed Of A Nitrogen ﻣﺟﻣوﻋﺔ أﻣﯾن – ﻣﻛوﻧﺔ ﻣن ﻧﯾﺗروﺟﯾن ﻣرﺗﺑط ﺑذرﺗﻲ bonded to two hydrogen atoms and a carbon ھﯾدروﺟﯾن وھﯾﻛل ﻛرﺑوﻧﻲ skeleton Phosphate Group—Consists of a ﻣﺟﻣوﻋﺔ ﻓوﺳﻔﺎت – ﺗﺗﻛون ﻣن ذرة ﻓوﺳﻔور ﻣرﺗﺑطﺔ ﺑﺄرﺑﻌﺔ phosphorus atom bonded to four oxygen ذرات أوﻛﺳﺟﯾن atoms Biological Molecules ھﻧﺎك أرﺑﻌﺔ أﺻﻧﺎف ﻣن اﻟﺟزﯾﺋﺎت اﻟﺣﯾوﯾﺔ Carbohydrates اﻟﻛرﺑوھﯾدرات Proteins اﻟﺑروﺗﯾﻧﺎت Lipids (اﻟﻠﺑﯾدات )اﻟدھون Nucleic Acids اﻷﺣﻣﺎض اﻟﻧووﯾﺔ ً ﺗﺳﻣﻰ أﯾﺿﺎ.ﺗﺳﻣﻰ ﻋﺎدة ﺑﺎﻟﺟزﯾﺋﺎت اﻟﻛﺑﯾرة ﻟﺣﺟﻣﮭﺎ اﻟﻛﺑﯾر Macromolecules Because of their large ﺑﺎﻟﺑوﻟﯾﻣﯾرات ﻷﻧﮭﺎ ﻣﻛوﻧﺔ ﻣن وﺣدات ﺑﻧﺎﺋﯾﺔ ﻣﺗﻣﺎﺛﻠﺔ ﻣﺗﻣﺎﺳﻛﺔ size. They are made from identical building This Presentation is NOT an Alternative to the Textbook! ﺑﻘوة blocks strung together ﺗﻌﺮﯾﻒ اﻟﻤﺼﻄﻠـــــﺢ اﻟﻣﺻطﻠــــــــــــــﺢ The building blocks are called monomers ﺗﺳﻣﻰ وﺣدات اﻟﺑﻧﺎء ﺑﺎﻟﻣوﻧﯾﻣﯾرات Dehydration Reactions, Which remove ﺗرﺗﺑط اﻟﻣوﻧﯾﻣﯾرات ﺑﺑﻌﺿﮭﺎ ﻟﺗﻛون ﺑوﻟﯾﻣﯾرات ﺑﺗﻔﺎﻋﻼت ﻧزع water اﻟﻣﺎء Polymers Are Broken apart by ﺗﻧﺣل اﻟﺑوﻟﯾﻣﯾرات ﺑﺎﻟﺗﻣﯾؤ )ﺑﺈﺿﺎﻓﺔ اﻟﻣﺎء( hydrolysis, the addition of water All biological reactions of this sort are ﻛل ھذه اﻟﻌﻣﻠﯾﺎت اﻟﺣﯾوﯾﺔ ﻣن ھذا اﻟﻧوع ﺗﺗوﺳط ﻓﯾﮭﺎ اﻹﻧزﯾﻣﺎت mediated by enzymes, which speed up اﻟﺗﻲ ﺗﺳرع ﻣن اﻟﺗﻔﺎﻋﻼت اﻟﻛﯾﻣﯾﺎﺋﯾﺔ ﻓﻲ اﻟﺧﻼﯾﺎ chemical reactions In Cells Dehydration Reaction ﺗﻔﺎﻋل ﻧزع اﻟﻣﺎء Hydrolysis اﻟﺗﻣﯾؤ أو اﻟﺣﻠﻣﺄة Monosaccharides, Such as glucose and اﻟﺳﻛرﯾﺎت اﻷﺣﺎدﯾﺔ ﻋﺑﺎرة ﻋن ﻣوﻧﯾﻣﯾرات ﺳﻛر ﻣﺛل اﻟﺟﻠوﻛوز Fructose واﻟﻔرﻛﺗوز ﯾﻣﻛن أن ﯾرﺗﺑط ﺳﻛران أﺣﺎدﯾﺎن )ﻣوﻧﯾﻣران( ﺑﺑﻌﺿﮭﻣﺎ اﻟﺑﻌض Disaccharide In a dehydration reaction ﻟﯾﻛوﻧﺎ ﺳﻛراً ﺛﻧﺎﺋﯾﺎ ً ﺑﺗﻔﺎﻋل ﻧزع اﻟﻣﺎء An example is a glucose monomer ﻣﺛﺎل ذﻟك ھو إرﺗﺑﺎط ﻣوﻧﯾﻣر اﻟﺟﻠوﻛوز ﺑﻣوﻧﯾﻣر اﻟﻔرﻛﺗوز ﻟﺗﻛوﯾن bonding to a fructose monomer to form اﻟﺳﻛروز )ﺳﻛر ﺛﻧﺎﺋﻲ ﺷﺎﺋﻊ( sucrose, a common disaccharide !This Presentation is NOT an Alternative to the Textbook ﺗﻌﺮﯾﻒ اﻟﻤﺼﻄﻠـــــﺢ اﻟﻣﺻطﻠــــــــــــــﺢ Starch is a storage polysaccharide اﻟﻧﺷﺎ ﻋﺑﺎرة ﻋن ﺳﻛرﻣﺗﻌدد ﺗﺧزﯾﻧﻲ وﯾﺗﻛون ﻣن ﻣوﻧﯾﻣﯾرات composed of glucose monomers and ﺟﻠوﻛوز وﯾوﺟد ﻓﻲ اﻟﻧﺑﺎت found in plants Glycogen is a storage polysaccharide اﻟﺟﻼﯾﻛوﺟﯾن أو اﻟﻧﺷﺎ اﻟﺣﯾواﻧﯾﻌﺑﺎرة ﻋن ﺳﻛرﻣﺗﻌدد ﺗﺧزﯾﻧﻲ composed of glucose, which is وﺗﺣﻠل اﻟﺣﯾواﻧﺎت اﻟﺟﻼﯾﻛوﺟﯾن ﻋﻧد، وﯾﺗﻛون ﻣن اﻟﺟﻠوﻛوز hydrolyzed by animals when glucose is اﻟﺣﺎﺟﺔ إﻟﻰ اﻟﺟﻠوﻛوز needed Cellulose is a polymer of glucose that اﻟﺳﯾﻠﯾﻠوز ﻋﺑﺎرة ﻋن ﺑوﻟﯾﻣﯾر ﺟﻠوﻛوزي ﯾﻛون ﺟدر اﻟﺧﻼﯾﺎ ﻓﻲ forms plant cell walls اﻟﻧﺑﺎﺗﺎت Chitin is a polysaccharide used by اﻟﻛﺎﯾﺗﯾن ﻋﺑﺎرة ﻋن ﺳﻛر ﻣﺗﻌدد ﺗﺳﺗﺧدﻣﮫ اﻟﺣﺷرات واﻟﻘﺷرﯾﺎت insects and crustaceans to build an ﻟﺑﻧﺎء ھﯾﺎﻛﻠﮭﺎ اﻟﺧﺎرﺟﯾﺔ exoskeleton Lipids are water insoluble (Hydrophobic, وھﻲ، (اﻟﻠﺑﯾدات ھﻲ ﻣرﻛﺑﺎت ﻻ ﺗذوب ﻓﻲ اﻟﻣﺎء )ﻛﺎرھﺔ ﻟﻠﻣﺎء or water hating) compounds that are ﺗﺣﺗوي ﻋﻠﻰ ﺿﻌف اﻟطﺎﻗﺔ اﻟﻣوﺟودة ﻓﻲ. ھﺎﻣﺔ ﻓﻲ ﺗﺧزﯾن اﻟطﺎﻗﺔ important in energy storage They contain اﻟﺳﻛﺎﻛر اﻟﻣﺗﻌددة twice as much energy as a polysaccharide Fats are lipids made from glycerol and اﻟدھون )اﻟﺳﻣن واﻟزﺑدة واﻟزﯾت( ﻧوع ﻣن اﻟﻠﺑﯾدات ﻣﻛوﻧﺔ ﻣن fatty acids ﺟﻠﯾﺳﯾرول وأﺣﻣﺎض دھﻧﯾﺔ Unsaturated This Presentation is NOT Fats : they an Alternative have to the fewer than ﺗﺳﻣﻰ ھذه اﻟﻣرﻛﺑﺎت ﺑﺎﻟدھون ﻏﯾر اﻟﻣﺷﺑﻌﺔ ﻷﻧﮭﺎ ﺗﺣﺗوى ﻋﻠﻰ ﻋدد Textbook! the maximum number of hydrogensn أﻗل ﻣن اﻟﻌدد اﻟﻛﻠﻲ ﻟﻠﮭﯾدروﺟﯾن ﺗﻌﺮﯾﻒ اﻟﻤﺼﻄﻠـــــﺢ اﻟﻣﺻطﻠــــــــــــــﺢ Fats with the maximum number of ﺗﺳﻣﻰ اﻟدھون اﻟﻣﺣﺗوﯾﺔ ﻋﻠﻰ اﻟﻌدد اﻟﻛﻠﻲ ﻟﻠﮭﯾدروﺟﯾن ﺑﺎﻟدھون hydrogens are called saturated fats (اﻟﻣﺷﺑﻌﺔ )ﻻ ﯾوﺟد ﺑﮭﺎ رواﺑط ﺛﻧﺎﺋﯾﺔ ﺑﯾن ذرات اﻟﻛرﺑون Phospholipids are structurally similar to fats and are an important component of ﺗﺷﺎﺑﮫ اﻟﻠﺑﯾدات اﻟﻔﺳﻔورﯾﺔ اﻟدھون ﻓﻲ ﺗرﻛﯾﺑﮭﺎ وھﻲ ﻣن اﻟﻣﻛوﻧﺎت all cells. For example, they are a major ﻋﻠﻰ ﺳﺑﯾل اﻟﻣﺛﺎل ھﻲ ﻣﻛون ھﺎم ﻟﻸﻏﺷﯾﺔ اﻟﺧﻠوﯾﺔ. اﻷﺳﺎﺳﯾﺔ ﻟﻠﺧﻠﯾﺔ part of cell membranes, in which they ﺣﯾث ﺗﺗﺟﻣﻊ ﻋﻠﻰ ھﯾﺋﺔ طﺑﻘﺗﯾن ﻣن اﻟدھون اﻟﻔﺳﻔورﯾﺔ cluster into a bilayer of phospholipids Steroids are lipids composed of fused اﻷﺳﺗروﯾدات ﻋﺑﺎرة ﻋن دھون ﻣﻛوﻧﺔ ﻣن ﺣﻠﻘﺎت ﺗرﻛﯾﺑﯾﺔ ﻣﺗداﺧﻠﺔ ring structures Cholesterol is an example of a steroid اﻟﻛوﻟﯾﺳﺗرول ھو ﻣﺛﺎل ﻟﻼﺳﺗروﯾدات اﻟﺗﻲ ﺗﻠﻌب دوراً ھﺎﻣﺎ ً ﻓﻲ that plays a significant role in the ﺗرﻛﯾب ﻏﺷﺎء اﻟﺧﻠﯾﺔ structure of the cell membrane Anabolic Steroids are synthetic variants ﺳﺗروﯾدات اﻷﯾض اﻟﺑﻧﺎﺋﻲ ﻋﺑﺎرة ﻋن ﺗوﻟﯾﻔﺔ ﺻﻧﺎﻋﯾﺔ ﻣن of testosterone that can cause A buildup اﻟﺗﯾﺳﺗﯾﺳﺗروﻧﺎت )ھرﻣوﻧﺎت اﻟذﻛورة( واﻟﺗﻲ ﺗؤدي ﻟﺑﻧﺎء اﻟﻛﺗﻠﺔ of muscle And bone mass اﻟﻌﺿﻠﯾﺔ واﻟﻌظﻣﯾﺔ Protein is a polymer built from various ﻣن20 اﻟﺑروﺗﯾن ﻋﺑﺎرة ﻋن ﺑوﻟﯾﻣر ﯾﺑﻧﻰ ﻣن ﺗواﻓﯾق ﺑﯾن combinations of 20 amino acid monomers ﻣوﻧﯾﻣرات اﻷﺣﻣﺎض اﻷﻣﯾﻧﯾﺔ This Presentation is NOT an Alternative to the Textbook!