Purple Futuristic Technology Presentation PDF
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Uploaded by FresherHyena
AIMST University
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Summary
This document summarizes the mechanism of action (MOA) and adverse drug reactions (AD) of several drugs. It likely discusses tuberculosis treatment and the associated medications. The document does not seem to be a traditional exam paper or textbook.
Full Transcript
MOA AD Inhibits the synthesis of mycolic acid in the cell wall of Common: Hepatotoxicity, pyrazinamide Mycobacterium tuberculosis, leading to bacterial cell hyperuricemia, arthralgia,...
MOA AD Inhibits the synthesis of mycolic acid in the cell wall of Common: Hepatotoxicity, pyrazinamide Mycobacterium tuberculosis, leading to bacterial cell hyperuricemia, arthralgia, death. gastrointestinal disturbances. Effective in the acidic environment of macrophages Severe: Hepatotoxicity, drug-induced where M. tuberculosis resides. hepatitis, photosensitivity reactions. Inhibits mycolic acid synthesis in M. tuberculosis Common: Peripheral neuropathy, INH by blocking enoyl-acyl carrier protein reductase. hepatotoxicity, drug-induced Key first-line drug for tuberculosis treatment. lupus. Acts as a cofactor in enzymatic reactions, including Generally well-tolerated at amino acid and neurotransmitter metabolism. recommended doses. pyridoxine Crucial in preventing peripheral neuropathy High doses may lead to associated with INH therapy. neurotoxicity, causing sensory neuropathy or sensory ataxia.
