Body Water & Fluid Compartments PDF

Body Water & Fluid Compartments M D S C 14 0 1 : E N V I RO N M E N T & H E A LT H FA R I D F YO U S S E F Learning Objectives 1. Know the divisions of the body fluid compartments 2. Know the percentage of the total body weight and body water found in each compartment. 3. Understand the princip...

Body Water & Fluid Compartments M D S C 14 0 1 : E N V I RO N M E N T & H E A LT H FA R I D F YO U S S E F Learning Objectives 1. Know the divisions of the body fluid compartments 2. Know the percentage of the total body weight and body water found in each compartment. 3. Understand the principle used in the measurement of the fluid compartments 4. List the materials used to measure fluid compartments 5. List the major anions and cations (identifying the predominant ones) found in each compartment Learning Objectives 6. Explain the forces governing movement of ions & fluid between the compartments 7. Describe Starling’s Hypothesis of fluid exchange 8. Define oedema 9. Explain how changes in Starling’s forces cause oedema 10. Describe the causes & consequences of over-hydration & dehydration of the fluid compartments and represent them on a Darrow-Yannet diagram What Does Water Do For You?  Infants have low body fat, low bone mass, Body Water and are 75% or more water Throughout Total water content declines throughout life Life ◦ Healthy males are about 60% water; healthy females are around 50% (why?) This difference reflects females’: ◦ Higher body fat ◦ Smaller amount of skeletal muscle In old age, only about 45% of body weight is water 80% 75% 50% 60% 45% (remember biological systems always exist within a normal range)  60-40-20 Rule Body Fluid Compartments Total Body Water (TBW) is distributed between: ◦ the intra-cellular fluid (ICF) and ◦ the extra-cellular fluid (ECF). ◦ TBW = ICF + ECF What structure separates these compartments? Transcellular fluid (